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Welcome to UISpace, The University of Ibadan Institutional Repository. A collection of theses, articles, books, videos, images, lectures, papers, data sets and all types of digital content originating from the University of Ibadan Nigeria. This repository is managed by the Kenneth Dike Library University of Ibadan, Nigeria.
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Effect of a stepped-care intervention delivered by lay health workers on major depressive disorder among primary care patients in Nigeria (STEPCARE): a cluster randomised controlled trial
(Elsevier Ltd., 2019) Gureje, O.; Oladeji, B. D.; Montgomery, A. A.; Bello, T.; Kola, L.; Ojagbemi, A.; Chisolm, D.; Araya, R.
Background Little is known about how to scale up care for depression in settings where non-physician lay workers constitute the bulk of frontline providers. We aimed to compare a stepped-care intervention package for depression with usual care enhanced by use of the WHO Mental Health Gap Action Programme intervention guide (mhGAP-IG). Methods We did a cluster-randomised trial in primary care clinics in Ibadan, Nigeria. Eligible clinics were those with adequate staffing to provide various 24-h clinical services and with regular physician supervision. Clinics (clusters), anonymised and stratified by local government area, were randomly allocated (1:1) with a computer-generated random number sequence to one of two groups: an intervention group in which patients received a stepped-care intervention (eight sessions of individual problem-solving therapy, with an extra two to four sessions if needed) plus enhanced usual care, and a control group in which patients received enhanced usual care only. Patients from enrolled clinics could participate if they were aged 18 years or older, not pregnant, and had moderate to severe depression (scoring ≥11 on the nine-item patient health questionnaire [PHQ-9]). The primary outcome was the proportion of patients with remission of depression at 12 months (a score of ≤6 on the PHQ-9, with assessors masked to group allocation) in the intention-to-treat population. This trial is registered with the International Standard Randomised Controlled Trials Number registry (ISRCTN46754188) and is completed. Findings 35 of 97 clinics approached were eligible and agreed to participate, of which 18 were allocated to the intervention group and 17 to the control group. 1178 patients (631 [54%] in the intervention group and 547 [46%] in the control group) were recruited between Dec 2, 2013, and June 29, 2015, among whom 976 (83%) were female and baseline mean PHQ-9 score was 13·7 (SD 2·6). Of the 562 (89%) patients in the intervention group and 473 (86%) in the control group who completed 12-month follow-up, similar proportions in each group had remission of depression (425 [76%] in the intervention group vs 366 [77%] in the control group; adjusted odds ratio 1∙0 [95% CI 0·70–1·40]). At 12 months, 17 (3%) deaths, one (<1%) psychotic illness, and one (<1%) case of bipolar disorder in the intervention group, and 16 deaths (3%) and one (<1%) case of bipolar disorder in the control group were recorded. No adverse events were judged to be related to the study procedures. Interpretation For patients with moderate to severe depression receiving care from non-physician primary health-care workers in Nigeria, a stepped-care, problem-solving intervention combined with enhanced usual care is similarly effective to enhanced usual care alone. Enhancing usual care with mhGAP-IG might provide simple and affordable approach to scaling up depression care in sub-Saharan Africa.
Pre-marital predictors of marital violence in the WHO World mental health (WMH) surveys
(Springer, 2019) Stokes, C. M.; Alonso, J.; Andrade, L. H.; Atwoli, L.; Cardoso, G.; Chiu, W. T.; Dinolova, R. V.; Gureje, O.; Karam, A. M.; Karam, G.; Kessler, R. C.; Chatterji, S.; King, A.; Lee, S.; Mneimneh, Z.; Oladeji, B. D.; Petukhova, M.; Rapsey, C.; Sampson, N. A.; Scott, K.; Street, A.; Viana, M. C.; Williams, M. A.; Bossarte, R. M.
Purpose Intimate partner violence (IPV) is a pervasive public health problem. Existing research has focused on reports from victims and few studies have considered pre-marital factors. The main objective of this study was to identify pre-marital predictors of IPV in the current marriage using information obtained from husbands and wives. Methods Data from were obtained from married heterosexual couples in six countries. Potential predictors included demographic and relationship characteristics, adverse childhood experiences, dating violence, and psychiatric disorders. Reports of IPV and other characteristics from husbands and wives were considered independently and in relation to spousal reports. Results Overall, 14.4% of women were victims of IPV in the current marriage. Analyses identified ten significant variables including age at first marriage (husband), education, relative number of previous marriages (wife), history of one or more categories of childhood adversity (husband or wife), history of dating violence (husband or wife), early initiation of sexual intercourse (husband or wife), and four combinations of internalizing and externalizing disorders. The final model was moderately predictive of marital violence, with the 5% of women accounting for 18.6% of all cases of marital IPV. Conclusions Results from this study advance understanding of pre-marital predictors of IPV within current marriages, including the importance of considering differences in the experiences of partners prior to marriage and may provide a foundation for more targeted primary prevention efforts.
Gender differential in inclination to donate brain for research among Nigerians: the IBADAN Brain Bank Project
(Springer Nature, 2019) Akinyemi, R.; Ojagbemi, A.; Akinyemi, J.; Salami, A.; Olopade, F.; Farombi, T.; Nweke, M.; Uvere, E.; Aridegbe, M.; Balogun, J.; Ogbole, G.; Jegede, A.; Kalaria, R.; Ogunniyi, A.; Owolabi, M.; Arulogun, O.
Background: Laboratory-based studies of neurological disease patterns and mechanisms are sparse in sub-Saharan Africa. However, availability of human brain tissue resource depends on willingness towards brain donation. This study evaluated the level of willingness among outpatient clinic attendees in a Nigerian teaching hospital.
Methods: Under the auspices of the IBADAN Brain Bank Project, a 43—itemsemi-structured interviewer—administered questionnaire was designed to evaluate knowledge, attitude, and beliefs of individuals attending Neurology, Psychiatry and Geriatrics Outpatient clinics regarding willingness to donate brain for research. Association between participants characteristics and
willingness towards brain donation was investigated using logistic regression models. Analysis was conducted using Stata SE version 12.0.
Results: A total of 412 participants were interviewed. Their mean age was 46.3 (16.1) years. 229 (55.6%) were females and 92.5% had at least 6 years of formal education. Overall, 109 (26.7%) were willing to donate brains for research. In analyses adjusting for educational status, religion, ethnicity, marital status and family setting, male sex showed independent association with willingness towards brain donation OR (95% CI) 1.7 (1.08–2.69), p = 0.023. Participants suggested public engagement and education through mass media (including social media) and involvement of religious and community leaders as important interventions to improve awareness and willingness towards brain donation.
Conclusion: The survey revealed low willingness among outpatient clinic attendees to donate brain for research, although men were more inclined to donate. It is imperative to institute public engagement and educational interventions in order to improve consent for brain donation for research.
Assessment of Compliance to Treatment among Ambulatory Asthmatic Patients in A Secondary Health Care Facility in Nigeria.
(The Society of Pharmaceutical Sciences and Research (SPSR)., 2012) Obasan, A.A.; Showande, J.S.; Fakeye, T.O
This study assessed the level of compliance using three different methods: pill count, self report and peak expiratory flow rate, in asthmatic patients attending a secondary health care facility. Self report (using a pre-tested structured questionnaire), peak expiratory flow rate and pill count were used to assess patient’s compliance and identify the factors which may be responsible for non compliance. Measurement of peak expiratory flow rate and the pill count were done at two different occasions. The data obtained was analysed using descriptive statistics. The study showed that the patients were prescribed a range of one to four drugs: 54% (3 drugs), 32% (2 drugs), 8% (4 drugs) and 2% (1 drug). The levels of compliance were 86.57% for self report and 83.56% for pill count (p > 0.05). Reasons given for non compliance were: apparent wellness (33.31%), forgetfulness (26.67%), cost of drugs (6.67%), dysphagia (6.67%), presence of non-disturbing symptoms (6.67%), side effects (6.67%), ignorance/fear of addiction (6.67%), perceived lack of benefit from treatment (6.67%), and lethargy towards chronic medication (6.67%). However, there was a significant difference in the readings of the peak expiratory flow rate measured at two different occasions (p < 0.05). The study showed no significant difference in the methods used to assess the level of compliance. Non compliance can be overcome by proper education of patients on the importance of complying with the administration of medication and proper usage of metered dose devices.
Spatial Distribution of Soil Moisture Content and Tree Volume Estimation in International Institute of Tropical Agriculture Forest, Ibadan, Nigeria
(Scientific Research Publishing, 2022) Alo A. A.; Agbor, C. F.; Jebiwott, A.; Temiloluwa, O.
The role of soil moisture in the survival and growth of trees cannot be overemphasized and it contributes to the net productivity of the forest. However, information on the spatial distribution of the soil moisture content regarding the tree volume in forest ecosystems especially in Nigeria is limited. Therefore, this study combined spatial and ground data to determine soil moisture distribution and tree volume in the International Institute of Tropical Agriculture (IITA) forest, Ibadan. Satellite images of 1989, 1999, 2009 and 2019 were obtained and processed using topographic and vegetation-based models to examine the soil moisture status of the forest. Satellite-based soil moisture obtained was validated with ground soil moisture data collected in 2019. Tree growth variables were obtained for tree volume computation using Newton’s formular. Forest soil moisture models employed in this study include Topographic Wetness Index (TWI), Temperature Dryness Vegetation Index (TDVI) and Modified Normalized Difference Wetness Index (MNDWI). Relationships between index-based and ground base Soil Moisture Content (SMC), as well as the correlation between soil moisture and tree volume, were examined. The study revealed strong relationships between tree volume and TDVI, SMC, TWI with R2 values of 0.91, 0.85, and 0.75, respectively. The regression values of 0.89 between in-situ soil data and TWI and 0.83 with TDVI ascertain the reliability of satellite data in soil moisture mapping. The decision of which index to apply between TWI and TDVI, therefore, depends on available data since both proved to be reliable. The TWI surface is considered to be a more suitable soil moisture prediction index, while MNDWI exhibited a weak relationship (R2 = 0.03) with ground data. The strong relationships between soil moisture and tree volume suggest tree volume can be predicted based on available soil moisture content. Any slight undesirable change in soil moisture could lead to severe forest conditions.