The human immune response to Plasmodium falciparum includes both antibodies that inhibit merozoite surface protein 1 secondary processing and blocking antibodies

Please use this identifier to cite or link to this item: http://ir.library.ui.edu.ng/handle/123456789/916

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DC Field	Value	Language
dc.contributor.author	Nwuba, R. I.	-
dc.contributor.author	Sodeinde, O.	-
dc.contributor.author	Anumudu, C. I.	-
dc.contributor.author	Omosun, Y. O.	-
dc.contributor.author	Odaibo, A. B.	-
dc.contributor.author	Holder, A. A.	-
dc.contributor.author	Nwagwu, M.	-
dc.date.accessioned	2018-10-08T10:18:25Z	-
dc.date.available	2018-10-08T10:18:25Z	-
dc.date.issued	2002-09	-
dc.identifier.issn	1098-5522	-
dc.identifier.other	Infection and Immunity 70(9), pp. 5328-5331	-
dc.identifier.other	ui_art_nwuba_human_2002	-
dc.identifier.uri	http://ir.library.ui.edu.ng/handle/123456789/916	-
dc.description.abstract	Malaria merozoite surface protein 1 (MSP1) is cleaved in an essential step during erythrocyte invasion. The responses of children to natural malaria infection included antibodies that inhibit this cleavage and others that block the binding of these inhibitory antibodies. There was no correlation between the titer of the antibody to the 19-kDa fragment of MSP1 and its inhibitory activity. These findings have implications for the design of MSP1-based vaccines.	en_US
dc.language.iso	en	en_US
dc.publisher	American Society for Microbiology	en_US
dc.title	The human immune response to Plasmodium falciparum includes both antibodies that inhibit merozoite surface protein 1 secondary processing and blocking antibodies	en_US
dc.type	Article	en_US
Appears in Collections:	Scholarly works

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