Baiyeroju, A. MUbah, J.N2018-10-162018-10-162004-060189-9171Nigerian Journal of Ophthalmology 12(1), pp. 14-18http://ir.library.ui.edu.ng/handle/123456789/2592Aim: To retrospectively assess the outcome of trabeculectomy performed using an intraoperative sponge soaked in 5-fluorouracil (50 mg/ml). Methods: Trabeculectomy with an intraoperative sponge soaked with 5-f1uorouracil (5-FU) was performed in 21 eyes of 14 patients. The reduction in intraocular pressure (lOP), complications and variations in visual acuity were noted. Results: The mean preoperative lOP was 31.5 ± 10.6 mmHg. The mean postoperative lOP was 7.3 ± 5.7mmHg on the second postoperative day and 17.5 ± 9.8mmHg at 3 months. Postoperative complications were mostly transient, with 33% of eyes requiring postoperative antiglaucoma therapy to reduce lOP. Visual acuity Improved postoperatively in 3 eyes, worsened in 9 eyes and remained the same in 9 eyes. Conclusion: Even though a small study, an intraoperative sponge soaked with 5-FU seems to be a safe and effective adjunct to trabeculectomy.en-US5-f1uorouracil,trabeculectomy,gl,Hlcomc1,NigerianArticle