Oniya, M. O.Omosun, Y. O.Anumudu, C. I.Nwuba, R. I.Odaibo, A. B.2018-10-082018-10-082011-041992-2248Scientific Research and Essays 6(7), pp. 1650-1655ui_art_oniya_igG_2011http://ir.library.ui.edu.ng/handle/123456789/1080Schistosoma haematobium infects school children in areas where the disease is endemic. This study was carried out to determine the reliability of IgG Enzyme-Linked Immunosorbent Assay (ELISA) as an immunodiagnostic tool, using whole antigen derived from Schistosoma eggs. Children of school going age living in Ipogun village, in south western Nigeria; a schistosomiasis endemic community; were used in this study. The sensitivity of the IgG ELISA in detecting positive cases was 68.0% and there was a significant correlation (P < 0.05) between IgG titres and the intensity of infection. However, the specificity was 59.3%, slightly lower than the sensitivity. Results from this study shows that IgG ELISA can be used as a diagnostic tool for determining S. haematobium infection, as it provides an evidence for the intensity of the infection in the infected individuals.enArticle