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Welcome to UISpace, The University of Ibadan Institutional Repository. A collection of theses, articles, books, videos, images, lectures, papers, data sets and all types of digital content originating from the University of Ibadan Nigeria. This repository is managed by the Kenneth Dike Library University of Ibadan, Nigeria.
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Gender differential in inclination to donate brain for research among Nigerians: the IBADAN Brain Bank Project
(Springer Nature, 2019) Akinyemi, R.; Ojagbemi, A.; Akinyemi, J.; Salami, A.; Olopade, F.; Farombi, T.; Nweke, M.; Uvere, E.; Aridegbe, M.; Balogun, J.; Ogbole, G.; Jegede, A.; Kalaria, R.; Ogunniyi, A.; Owolabi, M.; Arulogun, O.
Background: Laboratory-based studies of neurological disease patterns and mechanisms are sparse in sub-Saharan Africa. However, availability of human brain tissue resource depends on willingness towards brain donation. This study evaluated the level of willingness among outpatient clinic attendees in a Nigerian teaching hospital.
Methods: Under the auspices of the IBADAN Brain Bank Project, a 43—itemsemi-structured interviewer—administered questionnaire was designed to evaluate knowledge, attitude, and beliefs of individuals attending Neurology, Psychiatry and Geriatrics Outpatient clinics regarding willingness to donate brain for research. Association between participants characteristics and
willingness towards brain donation was investigated using logistic regression models. Analysis was conducted using Stata SE version 12.0.
Results: A total of 412 participants were interviewed. Their mean age was 46.3 (16.1) years. 229 (55.6%) were females and 92.5% had at least 6 years of formal education. Overall, 109 (26.7%) were willing to donate brains for research. In analyses adjusting for educational status, religion, ethnicity, marital status and family setting, male sex showed independent association with willingness towards brain donation OR (95% CI) 1.7 (1.08–2.69), p = 0.023. Participants suggested public engagement and education through mass media (including social media) and involvement of religious and community leaders as important interventions to improve awareness and willingness towards brain donation.
Conclusion: The survey revealed low willingness among outpatient clinic attendees to donate brain for research, although men were more inclined to donate. It is imperative to institute public engagement and educational interventions in order to improve consent for brain donation for research.
Assessment of Compliance to Treatment among Ambulatory Asthmatic Patients in A Secondary Health Care Facility in Nigeria.
(The Society of Pharmaceutical Sciences and Research (SPSR)., 2012) Obasan, A.A.; Showande, J.S.; Fakeye, T.O
This study assessed the level of compliance using three different methods: pill count, self report and peak expiratory flow rate, in asthmatic patients attending a secondary health care facility. Self report (using a pre-tested structured questionnaire), peak expiratory flow rate and pill count were used to assess patient’s compliance and identify the factors which may be responsible for non compliance. Measurement of peak expiratory flow rate and the pill count were done at two different occasions. The data obtained was analysed using descriptive statistics. The study showed that the patients were prescribed a range of one to four drugs: 54% (3 drugs), 32% (2 drugs), 8% (4 drugs) and 2% (1 drug). The levels of compliance were 86.57% for self report and 83.56% for pill count (p > 0.05). Reasons given for non compliance were: apparent wellness (33.31%), forgetfulness (26.67%), cost of drugs (6.67%), dysphagia (6.67%), presence of non-disturbing symptoms (6.67%), side effects (6.67%), ignorance/fear of addiction (6.67%), perceived lack of benefit from treatment (6.67%), and lethargy towards chronic medication (6.67%). However, there was a significant difference in the readings of the peak expiratory flow rate measured at two different occasions (p < 0.05). The study showed no significant difference in the methods used to assess the level of compliance. Non compliance can be overcome by proper education of patients on the importance of complying with the administration of medication and proper usage of metered dose devices.
Spatial Distribution of Soil Moisture Content and Tree Volume Estimation in International Institute of Tropical Agriculture Forest, Ibadan, Nigeria
(Scientific Research Publishing, 2022) Alo A. A.; Agbor, C. F.; Jebiwott, A.; Temiloluwa, O.
The role of soil moisture in the survival and growth of trees cannot be overemphasized and it contributes to the net productivity of the forest. However, information on the spatial distribution of the soil moisture content regarding the tree volume in forest ecosystems especially in Nigeria is limited. Therefore, this study combined spatial and ground data to determine soil moisture distribution and tree volume in the International Institute of Tropical Agriculture (IITA) forest, Ibadan. Satellite images of 1989, 1999, 2009 and 2019 were obtained and processed using topographic and vegetation-based models to examine the soil moisture status of the forest. Satellite-based soil moisture obtained was validated with ground soil moisture data collected in 2019. Tree growth variables were obtained for tree volume computation using Newton’s formular. Forest soil moisture models employed in this study include Topographic Wetness Index (TWI), Temperature Dryness Vegetation Index (TDVI) and Modified Normalized Difference Wetness Index (MNDWI). Relationships between index-based and ground base Soil Moisture Content (SMC), as well as the correlation between soil moisture and tree volume, were examined. The study revealed strong relationships between tree volume and TDVI, SMC, TWI with R2 values of 0.91, 0.85, and 0.75, respectively. The regression values of 0.89 between in-situ soil data and TWI and 0.83 with TDVI ascertain the reliability of satellite data in soil moisture mapping. The decision of which index to apply between TWI and TDVI, therefore, depends on available data since both proved to be reliable. The TWI surface is considered to be a more suitable soil moisture prediction index, while MNDWI exhibited a weak relationship (R2 = 0.03) with ground data. The strong relationships between soil moisture and tree volume suggest tree volume can be predicted based on available soil moisture content. Any slight undesirable change in soil moisture could lead to severe forest conditions.
An Investigation of the Factors That Motivated Illegal Settlements in the Mau Forest, Kenya
(Scientific Research Publishing, 2021) Jebiwott1, A.; Ogendi, G. M.; Alo A. A.; Kibet, R.
The Mau Forest has in the recent past elicited serious political and environmental debates regarding its conservation status, as the forest is fast dwindling and the repercussions felt widely across the country. The forest, regarded as the largest indigenous montane forest in east Africa, has been hard hit by land-use changes mainly extensive and ill-planned human settlements. To save the forest, the government has resorted to forced evictions of the settlers. We sought to understand the drivers and causes for the observed illegal settlements in the Mau Forest. To collect data, we conducted focus group discussions and administered household questionnaires on evictees in the South-West and Eastern Mau. Data were analyzed using descriptive and inferential statistics. The results of the binary logistic regression model indicate that Poverty (p = 0.000), Agricultural production (p = 0.000) and Land Given by Government (p = 0.018) contributed significantly to the prediction of people’s motivation of settling in the Mau Forest. In conclusion, population pressure, laxity in forest law enforcement and insecure land tenure and politics were identified as some of the factors that motivated the observed rise in illegal settlements in Mau Forest. Such information on the factors that led to the illegal settlements in Mau Forest would be useful for forest conservation policy makers and managers. It will be a basis upon which interventions can be undertaken to enhance sustainable forest management in Kenya and beyond.
Histopathologic pattern of posterior cranial Fossa tumours in a West African tertiary
(Zambia Medical Association, 2019) Salami, A.; Adeleye, A.; Oyemolade, T.; Ajani, M.; Usiholo, A.; Nweke, M.; Adeolu, A
Introduction: The posterior cranial fossa contains many vital structures and mortality of patients with tumours occurring in this area is high. Studies done in other geographic locations showed a higher occurrence of posterior cranial fossa tumours in paediatric patients while benign tumours were more commonly seen. Epidemiological data of tumours in this area in our environment is scarce. This study was done to ascertain the histopathologic pattern of tumours in the posterior cranial fossa in a predominantly black population.
Method: A ten-year retrospective study of histologically diagnosed posterior cranial fossa tumours seen in our hospital facility was done. A total of 72 cases in which neurosurgical intervention
was carried out were identified and this included all age groups. The age, sex, site of tumour and histological diagnosis were extracted from the patients' records.
Result: Adult patients predominated with 55.6% while the paediatric patients were 44.4%. The male to female ratio in the paediatric patients was 2.56:1 but the ratio was equal in the adult patients. WHO grade 1 tumours were the commonest tumours seen (45.8%) while grade II tumours were the least (4.2%). Medulloblastomas (20.83%), Pilocytic astrocytomas (18.6%) and Meningiomas (8.33%) were the commonest tumours seen. Commonest locations are in the cerebellar hemispheres (56.9%) and the fourth ventricle (13.89%).
Conclusion: Our study showed a higher occurrence of Medulloblastomas in contrast to other studies which have shown more of Schwannomas, a tumour type that was rare in this study. The relatively low number of metastatic tumours in this study may be due to lack of presentation of such patients.