Browsing by Author "Adeosun, A. A."

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Lead Accumulation and Distribution at Cellular level in Native Plants Growing on Battery Wastes Contaminated Sites in Ibadan, Nigeria.
(Sciencedomain International, 2017) Adeosun, A. A.; Adejumo, S. A.; Srivastava, P.
Introduction: Effective phytorextraction depends on the identification of fast growing plants that can tolerate and accumulate high concentration of metals in their tissue. This study was conducted to identify potential lead hyperaccumulators among the native plant species growing on two abandoned lead-acid battery waste-contaminated sites. Methodology: Plant samples were collected in triplicates from these sites. Pb accumulation in different parts, translocation (TF) and bioaccumulation factors (BCF) as well as cellular distribution of Pb among the cell organelles (cell wall, mitochondria, plastids, nucleus and soluble fraction) were determined. Results: Among the plant species (Gomphrena celosioides, Sporobolus pyramidalis, Imperata cylindrica, Chromolaena odorata, Cynodon. dactylon, Rhynchospora corymbosa and Eleusine indica) found on these sites, G. celosioides had the highest Pb concentration (12, 657 mg/kg ) in its shoot and the highest BCF (18.66) and TF (25.62) while others had TF and BCF values that were less than 1. S. pyramidalis and E. indica had lower Pb accumulation. Pb was mostly accumulated in the cell wall and there was an increase in the production of phenolics, flavonoids and chlorophyll. Conclusion: G. celosioides can therefore be described as a Pb hyperaccumulator and its Pb is mostly accumulated in the cell wall.
Nasopharyngeal carcinoma in Ibadan, Nigeria: a clinicopathologic study
(Pan African Medical Journal, 2020-06-20) Ogun, G. O.; Olusanya, A. A.; Akinmoladun, V. I.; Adeyemo, A. A.; Ogunkeyede, S. A.; Daniel, A.; Awosusi, B. L.; Fatunla, E. O.; Fasunla, A. J.; Onakoya, P. A.; Adeosun, A. A.; Nwaorgu, O. G.
Introduction: nasopharyngeal carcinoma is relatively common in our environment. It is one of the most difficult malignancies to diagnose at an early stage. The aim of the study was to determine the clinical features, clinical disease stage of nasopharyngeal carcinoma at presentation and at diagnosis as well as the histologic types at the University College Hospital, Ibadan, Nigeria. Methods: this was a ten year retrospective study of all histologically confirmed nasopharyngeal carcinoma between January 2007 to December 2016 using clinical and pathology records and files. Results: there were 73 cases. The male: female ratio was 1.7. The age of patients ranged from 12 to 80 years with a mean age of 39 ± 16 years. The median age at diagnosis was 40 years. The peak age group of occurrence was 40-49 years. The most common symptoms were namely epistaxis in 67.1% of patients at presentation, neck mass/swelling (64.4%) and nasal mass/obstruction (63.0%). Majority (54.8%) of the patients presented late with stage 3 or 4 disease. Most (94.5%) of the tumours were of the non-keratinizing squamous cell carcinoma subtype. The keratinizing and basaloid variants accounted for 4.1% and 1.4% of the tumours respectively. Conclusion: vague, non-specific symptoms make patients present at late stages of the disease, making it almost impossible to attempt cure. The dominant histopathological type is non-keratinizing squamous cell carcinoma and resembles that seen in most parts of Nigeria and endemic areas of the world
Pattern of ophthalmic consult from the ear, nose and throat ward of a tertiary hospital
(2009) Komolafe, O. O.; Adeosun, A. A.; Baiyeroju, A. M.
Objective: To study the pattern and indications for ophthalmic referral of patients with otorhinolaryngology problems. Method: A retrospective study of patients who were admitted into the Ear, Nose and Throat (ENT) ward of the University College Hospital, lbadan and had ophthalmic referral between July 2000 and June 2004. The parameters evaluated were the demography of the patient, indication for ophthalmic consult, and the contribution of the ophthalmologist towards the management of the patient. Results: Reports on 26 patients on whom ophthalmic consults were sent were available for review. This accounted for 3% of the patients admitted during the period under review. Fourteen (53.8% ) of the consults were sent on account of proptosis and 7 (26.9%) for complaints of poor vision. In 12 (46.2%) of these patients, the otorhinotarfngological diagnosis was sinonasal tumour. The ophthalmologist made positive contributions to the management of 20 (76.9%) of the patients. These included the use of lubricants/protective shield (6 [23.1%]), tarsorrhaphy (3 [11.5%]), antiglaucoma medication (2{7.7%}) and cataract extraction (2[7.7%]). Conclusion: Proptosis milked highest for ophthalmic consult from the ENT ward in this review. Close collaboration between subspecialties should be encouraged when managing visllally-threatening conditions. There is also the need for a standard referral protocol.
Seasonal variations in distribution, heavy metal uptake and proline production of native plants growing on Pb-contaminated site in Ibadan, South-Western,
(Ecological Society of Nigeria, 2015) Adejumo, S. A.; Adeosun, A. A.; Olaniyan, A. B.; Awodoyin, R. O.
Effects of seasonal variations on metal (Lead, Chromium and Cadmium) uptake, proline concentration, density and distribution of metallophytes inhabiting heavy metal polluted site in Ibadan, South-Western Nigeria were investigated. Vegetation surveys and Relative Importance Values (RIV) of different plant species were carried out both at the rainy and dry seasons. The metal uptake and partitioning in plants at different seasons as well as proline content were also determined. The results showed that the Relative Importance Value (RIV), metal uptake and proline production by plants varied depending on the prevailing environmental conditions. During both sampling seasons, same plant species were enumerated on the contaminated site. However, their RIV varied in the two seasons. Sporobolus. pyramidalis was prevalent in the rainy season while Imperata cylindrica had the highest RIV during the dry season. Heavy metal accumulation in different plant species also differed depending on the sampling period and higher concentrations of metals were accumulated during the rainy season compared to the dry season except in Gomphrena celosioides with Pb being the highest at both seasons. The proline concentrations were also species and season dependent. The concentrations varied in different plant species and G. celosioides accumulated more during both seasons while Eleucine indica and Rhyncospora corymbosa had higher concentrations during the dry season compared to rainy season. Plant species abundance, metal uptake and osmolyte production by metallophytes are therefore dependent on the prevailing environmental conditions.