Browsing by Author "Adewole, O. O."
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Item An algoritm for solving electromagnetic field equations by finite element method(Medwell Journals, 2007) Adetoyinbo, A. A.; Adewole, O. O.Describing the behaviour of electromagnetic frequency responses from vertically inhomogenous and anisotropic earth of 2-Dimensional structures energized finite sources is computationally laborious. Differential equations were derived and their numerical solutions also sought for the desired components of electric and magnetic fields. Also, expressions for the impedance and apparent conductivity were stated. An algorithm based on the finite element method for computing approximate numerical solutions for these problems were dealinated.Item Fortran algorithm for monitoring leachates and interpreting physico-chemical data of contaminants in ground water(2012) Adetoyinbo, A. A.; Adewole, O. O.A FOTRAN 90 algorithm was developed to interpret leachate geochemical data of polluted ground water in Lagos, based on 19 selected physico-chemical parameters adopted by the United States Geological and Environmental Survey Agency in compliance with the World Health Organization (WHO) prescribed standards for safe water consumption. By applying the Fortran program, the portability of leachates contaminated water were ascertained in compliance with WHO requirements.Item Spectrophotometric determination of Olanzepine following condensation reaction with p-dimethylaminobenzaldehyde(Elsevier B.V., 2014) Adegoke, O. A.; Thomas, O. E.; Makanjuola, D. M.; Adewole, O. O.A new, simple, cost-effective spectrophotometric method was developed for the determination of olanzapine in pharmaceuticals. The new method is based on formation of a yellow condensation product with p-dimethylaminobenzaldehyde, followed by measurement of absorbance at 410 nm. The reaction variables were optimized at 500C and 10 min. The reaction occurred at a stoichiometric ratio of 1:1. Absorbance was found to increase linearly with the concentration of the drug and formed the basis for quantification. The calibration graph was linear between 5 and 160 µgmL−1, and the correlation coefficient was 0.999. The apparent molar absorptivity was 0.6 ×103 L mol−1 cm−1, and the calculated Sandell sensitivity was 49.50 ng cm−2. The limits of detection and quantification were 6.6 and 20 µg mL−1, respectively. The method was validated in terms of accuracy, precision and reproducibility. The overall recovery was 98.4–101.5%, with an error of less than 1.7%. The proposed method was applied to the analysis of olanzapine in pure and dosage form and found to be of equivalent accuracy and precision to the official Indian Pharmacopoeia high-performance liquid chromatography method. There was no interference from commonly used excipients. The method could readily be adapted for use in developing countries where sophisticated equipment is not available.
