Browsing by Author "Akande-Sholabi W."

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    450 Barriers and enablers to medication deprescribing among older patients attending a geriatric clinic in southwestern nigeria: a cross-sectional study
    (2023) Akande-Sholabi W.; Ajilore C. O.; Olowookere O.O; Adebusoye L.A
    Introduction: Polypharmacy is an increasing health problem, leading to rise in morbidity and mortality, especially among older patients. De prescribing has been recommended for managing polypharmacy, but deprescribing medication in older patients is still uncommon (1). Safe deprescribing interventions can reduce exposure to inappropriate polypharmacy among older patients. However, few empirical data exist on the barriers and enablers to medication deprescribing among older patients in sub-Saharan African countries. Aim: This study aimed to assess the barriers and enablers of medication deprescribing among older patients. Methods: A cross-sectional study of 415 older patients aged ≥60 years, selected consecutively at the geriatric clinic in a Tertiary Hospital was carried out between May and July 2022. An interviewer-administered semi-structured questionnaire was used to obtain information on their socio-demographic characteristics, and barriers and enablers
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    Clinical and humanistic outcomes of pharmaceutical care interventions in diabetes mellitus: a systematic review and meta-analysis
    (2019) Segun J. Showande; Akande-Sholabi W.; Titilayo O. Fakeye.
    Background: Diabetes mellitus is a chronic disease for which life-long medications and care are needed. Effectiveness of care is related to good glycemic control, which is desired to forestall complications. Objective: This study evaluated the effectiveness of pharmaceutical care (PC) services provided by pharmacists in improving clinical and humanistic outcomes in diabetes mellitus patients. Method: Five databases (PubMed/Medline, Embase, Scopus, Cochrane Central Register of Control Trials and Google Scholar) were systematically searched for randomized controlled trials (RCTs) reported in English using free text and medical subject headings keywords. Studies which had PC intervention arm, a control group,type1 and type 2 diabetes mellitus patients; clinical and/or humanistic outcomes were included. For metaanalysis, standard mean difference evaluated with random effect model at P<0.05 was reported. Significant heterogeneity was further evaluated with sensitivity and subgroup analyses. Results: A total of 41 RCTs with 7,448 patients were eligible out of 1222 citations. PC intervention significantly lowered glycosylated hemoglobin, fasting blood glucose, systolic blood pressure, diastolic blood pressure, total cholesterol, and low density lipoprotein cholesterol (P < 0.05), with significant heterogeneity. PC intervention also improved self-care but medication adherence, disease knowledge and quality of life were not improved. PC services offered (patient education, identification and resolution of drug therapy problems, and pharmacotherapy evaluation) were not uniform across the studies. Conclusion: The review and meta-analysis showed that PC intervention is of great benefit to improve most clinical outcomes which may result in better disease management. A call is however made for standardized pharmaceutical care intervention.
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    Perception and Use of Herbal Medicines Among Clients Visiting Selected Community Pharmacies in Ibadan, Nigeria
    (2020) Akande-Sholabi W.; Iluyomade A.; Ilesanmi O.S.; Adisa R.
    Globally, there is an increasing trend in the use of herbal medicines. Despite, the benefit of its use, herbal medicines are not completely harmless. This study aims to evaluate the perception and use of herbal medicines among clients who visited selected community pharmacies in Ibadan metropolis, Nigeria. A cross-sectional survey was carried out among clients who patronized the selected community pharmacies, using a self-administered questionnaire. Demographic information, as well as perception and use of herbal medicines were evaluated. Data were summarized with descriptive statistics while K-W test was used for ranked variables at P< 0.05. The response rate was 90.7 %. Malaria 113 (58.9 %) was cited as the most common illness treated with herbal medicines. A total of 232 (76.8 %) had score  50.0 % indicating “good” perception on the use of herbal medicine. The level of education of the clients significantly influenced some of their perception towards herbal medicine. This include statement such as herbs can cure all diseases (K-W p=0.011), combination of the conventional drugs and herbs have no side effects (K-W p=0.002), and that side effect of synthetic drugs can be minimized with combination with herbs (K-W p=0.044). Most of the respondents had good perception about herbal medicine use. However, it was notable that the level of education significantly influenced the perception about the use of herbal medicines of some respondents. Public sensitization programme, and health education about the safety of herbal medicines, may be a useful means of improving the use of herbal medicine and reduce potential health risk.