Browsing by Author "Akinyinka, O. O."

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Syndromatic hepatic ductular Hypoplasia (Alagille syndrome) in a Nigerian: A Case Report
(1998) Akinyinka, O. O.; Akang, E. E. U.; Agbeja-Baiyeroju, A. M.; Osifi, B. O. A.||; Thurham, D.
We report what, as far as we are aware, is the first documented case of Alagille syndrome which is characterised by chronic cholestasis, characteristic facies, pulmonary stenosis and defects at the vertebral arch, in a Nigerian girl who presented at the age of two days and was followed up interminently for a period or 10.5 years. The biochemical indices suggestive of choiestasis in the patient improved with age while the height and weigh remained suboptimal. The patient had two percutaneous iiver biopsies with the second biopsy being consistent with paucity of interlobular biie duet syndrome. The characteristic facia features suggestive of the Alagille syndrome and clinical and echocardiographic evidence pulmonary stenosis were first observed at the age or 58) months. This syndrome although rare, should be considered in the differential diagnosis of conjugated hyperbilirubinaemia in Nigerian children.
An unusual presentation of congenital bronchoesophageal fistula
(2004-01-03) Atalabi, O. M; Falade, A. G.; Obajimi, O. M.; Akinyinka, O. O.; Lagundoye, S. B.; Ibinaiye, P. O.
We present the case of a 5-week-old neonate with multiple congenital abonormalities including a broncho-oesophageal fistula, which showed radiological features suggestive of congenital diaphragmatic hernia. Emergency limited barium swallow done was initially reported as a case of diapragmatic hernia. Autopsy revealed pus within the right lung, and a fistulous connection between the oesophagus and an intra-abdominal organ abnormality were seen, and an occipital meningomyelocoele was also confirmed.
Zinc phosphide (rodenticide) poisoning: A case report of deliberate self-harm in an eleven-year-old
(Paediatric Association of Nigeria, 2022) Akinlolu, A. A.; Asinobi, A. O.; Ademola, A. D.; Akinyinka, O. O.; Abioye, O.; Adelaja, A.; Philip, O. R.
Zinc Phosphide(Zn3P2) is a common rodenticide freely available in Nigeria for use against rodents. Occasionally human consumption occurs either accidentally or intentionally with potential consequences of multiorgan toxicity and death. An 11-year-old boy consumed an unknown quantity of zinc phosphide marketed as Push Out with the intention of committing suicide and killing some members of the family as his response to chastisement for a misdemeanour. Patient presented in the hospital 4 days after ingestion of zinc phosphide with a history of profound vomiting and abdominal pain. Laboratory evaluation showed evidence of hepatic dysfunction, acute kidney injury and elevated serum amylase. He was managed conservatively and discharged home after two weeks of admission. We report this case to emphasise the need for Paediatricians to consider ingestion of rodenticides as a differential diagnosis of hepatoxicity and pancreatic enzyme elevation, as well as to highlight the possibility of suicide among children. There is need to control the indiscriminate use of rodenticides, strengthen public health education on poisoning as well as establish Poison Information Centres in our environment.