Browsing by Author "Bakare, R. A."

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Microbes and morals, an unlikely love affair
(Ibadan University Press, 2012) Bakare, R. A.
Pattern if sexually transmitted Disease among HIV-! Infected commercial sex workers in Ibadan, Nigeira
(MEDIMOND, 2004) Fayemiwo, S. A.; Bakare, R. A.; Odaibo, G. N.; Oni, A. A.; Fasina, A. A.; Olaleye, D. O.; Sankale, J. L.; Kanki, P.
"This study evaluatcd the association of HXV-1 infection with some other sexually transmitted diseases (STDs) among fernaIe commercial sex workers. BIood samples were collected from 250 female commercial sex workers in Ibadan Oyo State, Nigeria and tested for the presence of HEV antibodies using ELISA and Western blot. Endocervical and high vaginal swab samples were also collected for microscopy and culture. The prevalence of HIV- 1 infection among CSWs in Ibadan, Nigeria was 25.6% with 2.8% having dual reactivity to HIV- 1 and HIV- 2. Bacterial vaginosis was the commonest STDs (32.8%) followed by herpes genitalis, vaginal candidiasis, gonorrhoea, trichornoniasis, chancroid,syphilis, tinea curiz, genital warts, Iympholgranuloma venerum (LGV) and scabics. Recurrcnt vaginal discharge, gcnital ulccr discascs as well as non-genital ulcer diseases (tinea curiz and scabies) were associated with increased risk of HIV infections. Access to prevention and prompt management of these STDs will reduce the spread of HIV."
Pattern of asymptomatic sexually transmitted infections in women undergoing hysterosalpingography for infertility evaluation in Ibadan Nigeria
(Society of Gynaecology and Obstetrics of Nigeria (SOGON)., 2013) Atalabi, O. M.; Fayemiwo, S. A.; Oladokun, A. A.; Bakare, R. A.
"The roles of gonorrhea and non-gonococcal urethritis due to Chlamydia trachomatis in the etiology of infertility due to tubal occlusion have been established by various studies. Hysterosalphingography WSG) is done to investigate tubal patency. This study was aimed at finding the prevalence of asymptomatic sexually transmitted infections (STIs) in women being investigated for infertility in a tertiary institution.Methods: This was a cross-sectional study of asymptomatic infertile women referred for pre-HSG screening. Detailed medical history, Endocervical and high vaginal swabs were collected to establish diagnosis of STIs following clinical examination and informed consent. These specimens were evaluated microscopically for Chlamydia trachomatis and bacterial vaginosis. Endocervical secretions were Gram-stained for intracellular Gram - Negative diplococci and suspected isolates were confirmed as Neisseriagonorrhoeae by standard laboratory methods. Results: There were 250 participants with a mean age of 34.6 years (SD = 5.4, range = 25 -49). The mean age of sexual debut of participants was 21.5 years (SD = 4.3). Fifty-six (22.5%) of the women engaged in oral sex while 53 (2 1.2 %) shared their spouses with other sexual partners. 1 7.7% had previous PID, 43.1% of them has vaginal discharge syndrome. The commonest ST1 was Vulvo- vaginal candidiasis (24.4%) and others were bacterial vaginosis (18.4%), Chlamydia cervicitis ( 17.6% ), trichomoniasis (11.2% ), and gonomhea ( 2.4 % ). Conclusion: The procedure of HSG is invasive and asymptomatic infections in the cervix can be dislodged and propagated by injectionof contrast to the fallopian tubes thus causing tubal blockage. Routine Per -HSG screening for occult STIs is encouraged to avoid iatrogenic Pelvic Inflammatoty Disease "
Sero-prevalence of hepatitis C virus among patients attending STD clinic in Ibadan, Nigeria
(2005) Oni, A. A.; Odaibo, G. N.; Ola, S. O.; Olaleye, O. D.; Bakare, R. A.
"In the tropics, hepatitis C virus (HCV) seroprevalence ranges from < 0.2% in whole Africa. A strong association between HCV and hepatitis B surface antigen (HBsAg)-negative chronic liver disease and hepatocellular carcinoma has been described. Hepatocellular carcinoma (HCC) is one of the most common cancers among Africans, and in Nigeria by 1970 the estimated rate was 6.6 per 100,000 populations per annum. Sexual transmission was regarded as a minor cause of HCV, the degree of which has not been properly evaluated in most environments. Since it has been established that sexual transmission is an important mode of acquisition of the infection, we therefore set out to find the seroprevalence of HCV among 95 patients attending sexually transmitted diseases (STD) clinic in University College Hospital, Ibadan, Nigeria with a view to recommending preventive and control measures of HCV in our community. The sera collected from these respondents were used for screening for syphilis using the VDRL test, and for HCV antibodies using the MONOLISA anti-HCV (Sanofi, Pasteur France). Mid-stream urine was collected from all participants, and urethral swabs from all male participants while endocervical and high vaginal swabs were collected from female participants. Ulcer swabs were collected from those with genital ulcers. The prevalence of HCV infection was found to be 37.9% in patients presenting with STDs. This comprised 38.9% of males and 61.1% females. This prevalence rate is very high compared with the rate in the general population and other “high-risk” groups in previous studies in the same environment. Factors associated with HCV infection in this environment include high heterosexuality, high level of education, and previous instrumentations such as in scarifications and termination of pregnancy. Prevention and control of STDs will definitely reduce HCV infection and hence the attendant consequences, particularly hepatocellular carcinoma, in our environment. "