Browsing by Author "Bolaji, O. M."

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Contribution of the indigenous health care givers to the herbal management of febrile illnesses in Rivers state, South-south, Nigeria
(2005-12) Ebong, O. O.; Ajaiyeoba, E. O.; Ononiwu, I. M.; Eteng, M. J.; Akinbiye, D. O.; Gbotosho, G. O.; Falade, C. O.; Bolaji, O. M.; Oladepo, O.; Osowole, O. S.; Happi, T. C.; Fawole, O. F.; Ogundahunsi, O. A. T.; Agbagwa, I. M.; Oduola, O.; Oduola, A. M. J.
This study was carried out in two rural communities; kaani and Boue, in Khana Local Government Area (LGA) and in one urban community, Elomo, in Elomo LGA, all in Rivers state, South-south, Nigeria. The investigations involved in-depth interview conducted with 104 health care givers comprising indigenous healers: herberlists, sellers of herbal remedies and community elders. Information was obtained on types of fevers (febrile illnesses) treated, symptoms and methods of establishing illnesses, and traditional herbs used in the prevention and treatment of febrile illnesses. On types of febrile illnesses treated, respondents presented the following: malaria (78.8%), typhoid (23.1%), yellow fever (21.2%), high fever (19.2%), convulsion (15.4%), and pregnancy fever (2.9%). Other illnesses treated were yellow eyes (4.8%), headache (11.5%), waist pain (14.4%), and joint pains (8.7%). Respondents determined whether a person had fever by the following: physical examination (85.4%), listening to patients' complaints (9.4%), through divination and inspiration (9.4%), while others (0.2%) were not quite explicit on their methods of diagnosis. On the treatment of febrile illnesees, respondents used herb teas (88.5%), herb powders (42.3%), incantation (3.3%), and performance of sacrifice (4.8%) or use of special fluids (27.9%). Majority of the respondents in describing the best herbal medicines for the treatment of febrile illnesses, 62.5% said that dogonyaro (Azadiracta indica) was the best medicine. Other responses were: lemon grass (Cymbepegon papaya) leaf/fruit (20.2%): guava (Psidium guajava) leaf (18.3%), akpagbogoro (Salacia nitida), 7.7%, plantain (Musa sapientum) sucker (6.7%), lipton tea (3.8%) and scent leaf (Ocimum gratissimum), 1.9%
Efficacy of herbal remedies used by herbalists in Oyo State Nigeria for treatment of Plasmodium falciparum infections a survey and an observation
(2004) Ajaiyeoba, E. O.; Falade, C. O.; Fawole, O. I.; Akinboye, D. O.; Gbotosho, G. O.; Bolaji, O. M.; Ashidi, J. S.; Abiodun, O. O.; Osowole, O. S.; Itiola, O. A.|; Oladepo, O.; Sowunmi, A.; Oduola, A. M. J.
In the course of evaluating the contribution of phytomedicine to possible drug discovery of antimalarial drugs, an ethnomedical survey of specialized children traditional clinics was done. In the observational multi center study, efficacy of eight different herbal remedies, each consisting of 3-8 ingredients and administered by herbalists were investigated in clients enrolled in the six traditional clinics in Oyo (urban center) and Otu (rural center) of Oyo State, Nigeria. The clients, aged between six months and fifteen years with clinical symptoms of malaria were enrolled in the clinics of the herbalists, as their usual practice. Oral informed consents were obtained from their parents or guardians. Microscopic diagnosis of malaria infection was used, to evaluate parasitaemia and validate efficacy of herbal remedies. Results of the analyzed shows that, of the 163 clients of the herbalists, only 62 (30 Oyo, 32 from Otu) had microscopically confirmed P. falciparum infection. Only results from 54 clients (29/30 (Oyo) and 25/32 (Otu) with P. falciparurn infection could be evaluated. Plasmodium falciparum infection in 88% (23/29) of clients from Oyo responded to treatment with the herbal remedies while cure rate in clients from Otu was 42% (13/25). Parasite densities ranged from 171 to 53,613 parasites/ul blood and 87 to 36,209 parasites/ul blood in patients from Oyo and Otu respectively. The herbalists administered the remedies and Gossypium arboreum, Anarcudium occidentalis, Citrus medica, Phyllanthus amarus and Lippia multiflora were the main ingredients in the efficacious remedies. The herbalists gave detailed descriptions of each of the 8 herbal remedies proffered. The results confirm the efficacy of two of the eight herbal remedies, thereby validating the role of ethnomedicine as a possible source for the discovery of new cherno-therapeutic agents in the treatment of P. falciparum malaria.
Nigerian antimalarial ethnomedicine 2: Ethnobotanica surveys of herbal remedies used in the treatment of febrile illnesses in the middle belt of Nigeria
(2002) Ajaiyeoba, E. O.; Osowole, O. S.; Oduola, O .O.; Ashidi, J. S.; Akinboye, D. O.; Gbotosho, G. O.; Falade, C. O.; Ogundahunsi, O. A. T.; Fawole, O. I.; Bolaji, O. M.; Falade, M. O.; Oladepo, O. O.; Itiola, O. A.; Oduola, A. M. J.
An ethnobotanical survey was conducted among residents of Gboko (urban) and Katsina Ala ( rural) local government areas in Benue state located in the middle belt of Nigeria. The Katsina-Ala and Gboko communities belong to the Tiv ethnic group. Documentation of the use of herbs as alternative in the treatment of fevers and identification of potential phytomedicines against malaria was done. Semi-structured questionnaires and focus group discussion guides were used to obtain information on description of febrile illness and utilization of herbal remedies for prevention and treatment. A total of 499 respondents comprising of mothers, fathers, community leaders/elders, herbs sellers and traditional healers were interviewed in the study. In the study, 9 types of febrile illnesses were proffered. The five most common type of febrile illnesses described were malaria (37.3%), yellow (28.8%), typhoid (27.3%), high fever (3.4%) and ordinary fever (0.5%). Perceived causes of febrile illness included mosquito bites, contamination of water and food, among others. Headache, general weakness, yellow coloration of eyes/uririe, elevated body temperature and diarrhoea, were the most common symptoms associated with febrile illnesses outlined by the respondents. Furthermore, malaria (81.5%) and high fever (57%) were reported to be common during the rainy season while typhoid (52%) is common during the dry season. Yellow fever was said to be non-dependent on season. Respondents believed children were more at risk of malaria compared with the other types of febrile illnesses mentioned. The respondents indicated that herbal recipes were effective treatment for Febrile illness. From the 105 recipes compiled, Azadirachto indica, Ficus thonningii, Annona senegalensis and Cymbopogon citratus were the most frequent herbs mentioned. Leaf (60.4%), was the most common part of plants used while boiling (92.5%), was frequently mentioned as method of herbal remedy preparation. The main route of administration of remedies mentioned was oral administration (97.9%). The study confirms the potential contribution of Phytomedicine to management of febrile illnesses, including malaria in the Tiv ethnomedicine.