Browsing by Author "Eyarefe, O. D."

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Ameliorative effects of Musa sapientum peel extract on acetic acid-induced colitis in rats
(The Egyptian German Society for Zoology, 2016) Adegoke, G. A.; Onasanwo, S. A.; Eyarefe, O. D.; Olaleye, S. B.
Ameliorative effects of Musa sapientum peel extract (MSPE) were studied on Acetic Acid (AA)-induced colitis in rats. From a dose response study, the effective and yet, safe for the treatment of AA-induced colitis in rats was determined, and also, a further study was carried out to determine the effective fraction(s) of MSPE that will be useful in the treatment of AA induced colitis in rats. Colitis was induced with 0.2 ml of 6% acetic acid through a lower abdominal laparotomy. Treatment with graded doses of methanolic extract of dried peel of Musa sapientum (MS) (50, 100 and 200 mg/kg) for 7 days in AA induced colitis in rats showed 50 mg/kg as an optimal effective dose for the healing of AA induced colitis in rats. This dose (50 mg/kg) was further studied with fractions of MSPE in comparison to a standard drug (sulfasalazine) of the same dose (50 mg/kg) on AA induced colitis in rats for 18 days. Colitis was assessed using stool consistency, macroscopic gross score and histological studies. Normal stool consistency was seen early in treated animals as compared with control; MS peel (crude extracts and fractions) significantly reduced macroscopic and histologic colon tissue damage in a manner similar to that of sulfasalazine. The results from these findings suggests that MSPE fractions of ethyl acetate and methanol may be effective in reducing both macroscopic and histological damage in a manner similar to sulfasalazine, and that it may be helpful in the treatment of colitis
Ano-rectal malformations in pigs: a report of a striking case in an eight-week-old piglet (a case report)
(2011) Eyarefe, O. D.; Abiola, J. O.; Oguntoye, C. O.; Ayoade, G. O.
Anorectal malformations are rare congenital disorders in animals. In swine, atresia ani occurs with an incidence of 0.1—1.0 % and it is the most important cause of intestinal obstruction in that species. This paper reports a striking case of atresia ani et recti in an eightweek- old piglet. The surgical management and preventive measures are discussed
Cosmetic tail docking: an overview of abuse and report of an interesting case
(Cross Mark, 2016) Eyarefe, O. D.; Oguntoye, C. O.
Background: This paper presents an overview of the global controversies surrounding cosmetic tail docking in puppies, some observed inconsistent practices among dog breeders and Veterinarians in West Africa, and the need for the African Veterinary Profession to take a decisive position on the cosmetic docking procedure. Case presentation: An interesting report of observed complications associated with cosmetic tail docking in a 3 week old male Boerboel is reported alongside the management of the ensuing complications. Conclusion: This paper highlights the still prevalent practice of cosmetic tail docking and seeks to enlighten clinicians towards stemming its abuse in Africa
Dog breeds acquisition and owners’ awareness of associated surgical conditions in Nigeria
(Academic Journals, 2018-07) Eyarefe, O. D.; Adetunji, A. G.
The study evaluated dog owners’ awareness of breed-associated surgical conditions in Nigeria as indices for breed choice with structured pre-tested questionnaires administered to dog owners in 17 states of Nigeria. Alsatians (36.8%) and Rottweiler (13%) breeds were mostly possessed by owners. The majority of the respondents were females (60.4%) owners. Lagos (53.4%) and Oyo (52.1%) states had the highest number of respondents while Kaduna (1.25%), Enugu (1.25%), Ekiti (1.25%), and Plateau (1.25%) states had the lowest. Most of the respondents (84.8%) are within the age bracket of 16 to 30 years, while 46.6% were University graduates and 90.8% had kept dogs previously. Factors that influenced dogs’ breed choices included: Body size (66.6%), coat colour (78.6%), natural intelligence (96.4%), information on the internet about the breed (54.6%), breed type possession by a close relative (53.4%), information regarding animal care from the Veterinarian (39. 2%), and recommendation by friends (42.6%). Respondents routinely visited the veterinary health centre for a general check-up and disease prevention (79.6%), vaccination and routine worming (79.2%), and treatment of diseases (79.8%). Respondents had varying knowledge of common surgical diseases: Cruciate ligament rupture (13.6%), gastric dilation/volvulus (13.6%), portosystemic shunt (15.0%), entropion (17.7%), ectropion (17.7%), osteochondrosis dessicans (17.7%), tracheal collapse (17.7%) etc. Only 10.9% of the respondents were aware of persistent health challenges in their dogs, while 84.4% of the respondents were uninformed of their dog breed predisposition to certain health challenges, and 82.3% of respondents were not aware of their dogs’ predisposition to any surgical disease. These findings imply a need for veterinarians’ input in dog choices, for recommendation of legislation mandating potential owners to seek out information about health care conditions of prospective dog breeds from authorized sources before possession to forestall frustrations, and avoidance of ultimate pet abandonment associated with management cost and social adjustment following surgical diseases
Effects of varying doses of tramadol on ketamine anaesthesia for laparocaecectomy in layer chickens
(Academic Journals, 2015-12) Eyarefe, O. D.; Oguntoye, C. O.
The effects of a high ketamine dose (15 mg/kg) and a low ketamine dose (10 mg/kg) combined with two separate doses of tramadol (10 and 5 mg/kg) were studied in chickens. Seventeen layer chickens (Isa brown breed) presented for laparo-cecectomy associated with feed trials were randomized into Ketamine-Lignocaine (KL) group (15 mg/kg ketamine)- 5 chickens, Tramadol-Ketamine-Lignocaine (TKL) group (10 mg ketamine plus 5 mg/kg tramadol)- 5 chickens and Tramadol-2-Ketamine-Lignocaine (TTKL) group (10 mg ketamine plus 10 mg/kg tramadol)- 7 chickens. All chickens had 2% lignocaine incision site infiltration to provide additional analgesia. Onset of drug action (OAN), Duration of recumbency (DR), heart rates (HR), respiratory rates (RR) and cloacal temperature (CT) were evaluated as anaesthetic monitoring indices. The trend for OAN was KL (3.3±0.4 min) >TKL group (4.0±3.0 min) > TTKL group (8.2±2.5 min). DR was KL group (110.3±20.8 min) > TTKL group (81.2±5.5 min) > TKL group (62.6±4.7 min). The mean variation of pre-anaesthetic and anaesthetic values of HR was not significant, although the KL group had the lowest HR. Observed fall in RR with TTKL < TKL< KL was not significant (P>0.05) among the groups. A statistically none significant (P>0.05), none life threatening fall in temperature was also observed among the groups. In the absence of inhalatory anaesthesia, 10 mg/kg ketamine combined with tramadol (5-10 mg/kg) and lignocaine infiltration may be a preferred anaesthetic protocol for non-protracted surgical procedures in chickens
Evaluation of canine dental health problems in Ibadan, Nigeria
(2014-09) Eyarefe, O. D.; Oni, A.F.; Emikpe, B.O.
Clinical evaluation for Dental Disease Conditions (DDC) in companion animals is an integral aspect of routine dental health care procedure in veterinary practice which often is less practice in Nigeria. This study evaluated the occurrence of DDC and possible inciting causes with a focus of providing a meaningful basis for canine dental health care in Nigeria. Fifty-seven dogs (30 males and 27 females) made up of 10 different breeds and presented at 3 major Veterinary Hospitals in Ibadan, Nigeria were assessed for periodontal disease (PD), dental calculus (DC), dental abrasion (DA) and their association with other systemic diseases using Dental probe, Glucometer, Urinalysis strip and PD survey questionnaire. Data were analyzed using descriptive statistics and correlation at > 0.05 level of significance. The prevalence of PD was the highest (82.46%) while DC was 80.70% and DA, 57.89%. PD was observed to be more common in male (83.33%) dogs, while calculus formation and dental attrition were more common in female dogs. The incidence and severity of dental disease conditions increased with age. There was a positive correlation (p=0.04) between PD and DC and between DC and DA (p=0.00). The order of nutritional inciting cause of PD, DC and DA is compounded food > home food > waste from eateries. This investigation showed a high incidence of DDC in dogs with no dental health care and nutrition could be an inciting cause. This showed that there is need for patients’ dental health care in veterinary practice in Nigeria
Healing potentials of oral moringa oleifera leaves extract and tetracycline on methicillin resistant staphylococcus aureus infected wounds of wistar rats
(Physiological Society of Nigeria, 2015) Eyarefe, O. D.; Idowu, A.; Afolabi, J. M.
Summary: The effects of oral dose of aqueous extract of Moringa oleifera and tetracycline antibiotics on cutaneous wounds infected with Staphylococcus aureus were studied in eighteen adult wistar rats (159±31.5g) randomized into three groups: Group A, n = 6, Moringa oleifera-(300 mg/kg). Group B, n = 6, tetracycline (9.4 mg/kg) and Group C, n = 6, Sterile water (control). Six millimetres diameter nape wound, created on each rat under 2% xylazine (5 mg/kg) and 5% ketamine (35 mg/kg), was contaminated with Staphylococcus aureus (108 Colony Forming Unit (CFU). Following infection, treatment was commenced with daily oral dose of test preparations and the wounds were evaluated every other day i.e., day 3, 5, 7, 9, 11, 13 and 15 for wetness (wound exudation), wound edge oedema, hyperaemia, granulation tissues and contraction (diameter). Severe wound exudation existed in all the groups between days 0-3 (p = 1.00). A significantly less (p<0.05) wound exudation was observed at days 3-5 (p = 0.000) and 5-9 (p = 0.003) (Control< Tetracycline Moringa> Tetracycline). Differences in wound diameter was not significant except at days 5-9 (p = 0.013) (Control> Moringa >Tetracycline). Oral doses of Moringa oleifera extract (300mg/kg) and tetracycline (9.4mg/kg) are not effective as antimicrobial or immune-boosting agents to enhance healing of wounds infected with Staphylococcus aureus and hence not recommended for rapid clearance of Staphylococcus aureus infected wounds
Intersex piglet with bilobed urinary bladder in Kumasi, Ghana: a case report
(2017) Eyarefe, O. D.; Atawalna, J.; Emikpe, B. O.; Folitse, R.; Dei, D.; Duduyemi, B.; Okungbowa, S.; Okai, D.
This paper reports a case of a true intersex in a pig in Kumasi, Ghana. The diagnosis was based on gross and histomorphological assessment of the genital organs which consist of a left ovary, two uterine horns and body of uterus, along with a right testis without an epididymis. Vagina and vulva were also absent. A perineal scrotal pouch and a tubular tract connection with an intra-abdominal urinary bladder conducting urine through a miniature paraphimotic sigmoid shaped penis were observed. A rectal prolapse was consequent to rectal compression by the inadequately voided urinary bladder. Gonadal hormonal profiles were analysed and compared in the true intersex and those of the males and female siblings using standard techniques. The embryologic, reproductive, and swine production cost implications of intersex were discussed
Managing a necrotic limb of african dwarf crocodile (osteolaemus tetraspis) in Ibadan zoological garden: a case report
(2012) Eyarefe, O. D.; Oguntoye, C. O.; Omobowale, T. O.
Managing bite wounds in male a Mona monkey (cercopithecus mona)
(2012) Eyarefe, O. D.; Oguntoye, C.O.
This paper reports on the management of bite wounds inflicted on an adult male mona monkey by two other males in an attempt to mate the only female in the group. The deep laceration wounds which were at the left cranial thoracic and left caudal abdominal walls, the lateral aspect of the right thigh, the planter surface of the right fore limb and the right triceps muscle were managed with honey incorporated bandage dressings and delayed primary closure with sutures. The unique wound management procedure especially in wild life species,as well as the need to prevent group fight among wild life species in captivity especially mona monkeys through understanding of their social interactive structure formed the objectives of this report. Information acquisition by Zoo Veterinarians and managers, on social interaction among wild life species could help in preventing injuries, reducing cost of zoo animal keeping and conserving the few wild species presently available in our zoological gardens and game reserves
Morbidity in Nigerian local cats after ileocolic valve or ileocolic valve and ileal resection
(2011) Eyarefe, O. D.; Akinrinmade, J. F; Wojuoia, O. A.
The morbidity of excision of the ileocolic valve (Group A), and the ileocolic valve with thirty percent (30%) distal ileal segments (Group B) were evaluated and compared in six adult local cats anaesthesized with xylazine (0.4 mg/kg) and ketamine hydrochloride (22 mg/kg). A non-significant fall (P>0.05) in the haemogram (PCV, Hb, RBC, and WBC), total serum proteins (albumin and globulin) and body weights were recorded among cats in groups A and B, following six weeks of post-operative monitoring. Samples of feces from both groups were non-bloody, non-mucoid and have normal to soft consistency with evidence of improvement over time. The improvement in fecal consistency, body weight and haematological picture over the period of post-operative management was adjudged to be consistent with adaptive changes in the residual intestinal segments. The observed clinical features are discussed in relation with those of massive intestinal resection in cats, dogs and humans. It was concluded that ileocolic valve resection produced little or no detrimental effects on bowel functions of local cats, and local cats could tolerate ileocolic valve with thirty percent (30%) distal ileal resection provided the proximal intestinal segments are intact
Pathological and immunohistochemical evaluation of wound healing potential of Nigerian bee propolis in albino rats
(Springer-Verlag London, 2018) Eyarefe, O. D.; Ozota, C. A.; Jarikre, T. A.; Emikpe, B. O.
This study evaluated the efficacy of the Nigerian bee propolis as a wound healing agent, on full thickness skin wounds of healthy adult male (150.0 ± 0.5 g) albino rats randomly divided into three treated groups (propolis extract (PE), propylene glycol (PG), silver sulfadiazine) and an untreated group. Each rat had three circular full thickness skin wounds created on the cranial, middle, and caudal surface of the rat’s dorsum. The wounds in each group were topically treated with bee propolis extract (PE, 0.1 ml), propylene glycol (PG, 0.1 ml) and silver sulfadiazine (SS, 0.1 ml) twice daily for 21 days, except the untreated group (UT). The wounds were evaluated for gross (exudation, edema, hyperemia, wound contraction), histologic (granulation, angiogenesis, fibroplasia, epithelialization), and expression of epidermal growth factor (EGF) using standard techniques. Data was descriptively summarized as percentages, mean and analyzed using Chi-square and analysis of variance at α = 0.05.Wound edge edema (WEE), hyperemia, and exudation were prominent in all the groups between days 0–2.WEE was significantly less on day 3 in the PE (14%) and SS (14%) groups, compared with the PG (35%) and UT (66%) groups. Wounds treated with PG and UT were significantly more hyperemic than those with PE and SS. Wound contraction was significantly less on day 2 in the UT wounds when compared to the treated wounds (PE = 12.63%, SS = 2.22%, PG = 4.94%, and UT = − 2.82%). The wound contraction was remarkable between days 4–8 in the PE- and SS-treated wounds (PE > SS > PG > UT). The microscopic changes at days 4, 8, 12, 16, and 21 showed significant evidence of epithelial proliferation, improved angiogenesis, granulation, and fibrous connective tissue in the PE- and SS-treated rats compared with the negative controls. The inflammatory response showed that the PE group had the highest amount of macrophages and leucocytes on day 4 with the trend being PE > SS > PG > UT. Neutrophils regressed in the treated wounds on day 8 but were consistently high in the untreated group from days 4–16. The immunohistochemical evaluation showed that the intensity of EGF was consistently high in the SS- and PE-treated wounds. Nigerian bee propolis extract accelerated wound healing similar to that of silver sulfadiazine based on wound healing indices and is therefore recommended for the management of wounds especially in low-income communities where propolis is available and affordable
Pet owners’ perception and satisfaction of surgery services and outcomes at the ashanti regional veterinary clinic, Kumasi, Ghana
(2015-01) Eyarefe, O. D.; Emikpe, B.; Dei, D.
Aim: To study pet owners’ perception of surgery services and client satisfaction in Ghana in order to improve the quality of surgery services. Method: Self-administered questionnaires were administered to owners of pets that were presented for surgery at the Ashanti Region Veterinary Clinic (ARVC). Data generated were presented in percentages with their standard error of means. Result: 80% of the respondents were satisfied with the cost of surgical management, while 92% were satisfied with doctors’ staff attitude. Conclusion: The study revealed an overall client satisfaction of veterinary surgical services at the ARVC however surgeon–client communication need to be improved with respect to knowledge of surgical procedure prior to surgery. Periodic evaluation of veterinary services by service consumers should be encouraged to facilitate service improvement toward better animal healthcare delivery in Ghana
Retrospective Study of Prevalence and Pattern of Surgical Conditions Presented at the Ashanti Regional Veterinary Clinic, Kumasi, Ghana
(IDOSI Publications, 2014) Eyarefe, O. D.; Dei, D.
Case records of animal patients presented for surgery at the Ashanti regional veterinary clinic, Kumasi, Ghana, within a seven year (1997-2013) period were studied for surgical disease prevalence and pattern among animal species. The age, sex and breeds, as well as, quarterly distribution of surgical cases were also evaluated. A gradual increase in numbers and types of surgical conditions were observed across the years studied, with the least prevalence in 2007 (2.6%) and the highest in 2013 (29.2%).Wounds /trauma cases were highest (41.0%) and vaginal prolapse least (0.1%) among surgical cases managed. Most surgical conditions were in canine species (96.0%), while the rest (3.8%) were in feline (2.4%), equine (0.5%), caprine (0.4%) and ovine (0.4%) species. Among the twenty–one dog breeds presented for surgical management, the local breed (mongrel) had the highest occurrence (40.2%) of surgical conditions, while the poodle (0.1%), Daschund (0.1%) and Labrador (0.1%) had the least. Male dogs (57%) were presented more for surgery than females (35%). Also, younger dogs (57%) had more surgeries than adult dogs (35%). Most surgical cases were presented in the fourth quarter (October–December) (31.4%) and the least in the second quarter (April –June) (18.5%). The implications of the data to regional, national and global planning and training of Veterinarians on animal surgical disease management were discussed
Risk factors, prevention and control strategies for surgical site infections in veterinary practice in Nigeria: A review
(Academic Journals, 2016-08) Eyarefe, O. D.
Surgical site infections (SSIs) are surgery associated nosocomial infections with multifactorial etiologies. They are adverse events that have placed heavy burden on surgery universally and have bedeviled veterinary surgery practice in Nigeria for decades, with consequent severe morbidity, mortality, financial and psychological burden on animal owners. In this paper, information on current universal trend of SSIs, including risk factors, prevention and control strategies was reviewed with emphasis on principles and practice among small animals and equine surgery practitioners. Principles guiding surgical suite design, surgical team, instruments/equipment, and patient preparation, were emphasized. It was concluded that imbibing the principles and practice of SSIs prevention strategies in Nigeria veterinary hospitals and clinics would impact positively on the veterinary health care system and the society the Veterinarian is committed to serve
Splenic lymphoma in an adult local bitch: a case report
(2002) Oni, S. O.; Akinrinmade, J. F.; Ajadi, R. A.; Eyarefe, O. D.; Olaifa, A. K.
A four-year old local dog weighing 12kg was presented four days after signs of persistent anorexia and dullness were observed. Physical examination of the bitch revealed a circumscribed distension of the left lateral abdomen about 5cm caudal to the rib cage, which on palpation appeared firm, discrete and nodular but painless. X-rays views confirmed that the mass was intrasplenic and had a fat density. Blood and urine samples were analysed, the result of which showed proteinuria, bilirubinuria and neutrophilic leucocyosis. Exploratory laparotomy and spleenectomy were carried out. The extirpated spleen had pendunculated projection. The biopsy of the spleen revealed that the tumour is a lymphoma
Surgical asepsis
(Ibadan University Press, 2014) Eyarefe, O. D.