Browsing by Author "Obajimi, M. O."

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Abdominal ultrasonography inHIV/AIDS patients in southwestern Nigeria.
(BioMEd Central Limited, 2008) Obajimi, M. O.; Atalabi, M. O.; Ogbole, G. I.; Adeniji-Sofoluwe, A. T.; Agunloye, A. M.; Adekanmi, A. J.
"Though the major target of the HIV-virus is the immune system, the frequency of abdominal disorders in HIV/AIDS patients has been reported to be second only to pulmonary disease. These abdominal manifestations may be on the increase as the use of antlretroviral therapy has increased life expectancy and improved quality of life. Ultrasonography is an easy to perform, non invasive, inexpensive and safe imaging technique that is invaluable in Africa where AIDS is most prevalent and where sophisticated diagnostic tools are not readily available. Purpose: To describe the findings and evaluate the clinical utility of abdominal uitrasonography in HIV?AIDS patients in Ibadan. Methods:A Prospective evaluation of the abdominal ultrasonography of 391 HIV-positive patients as well as 391 age and sex- matched HIV-negative patients were carried out at the University College Hospital, Ibadan.Results: Of the 391 cases studied, 260 (66.5%) were females; the mean age was 38.02 years, (range 15-66 years). The disease was most prevalent in the 4th decade with an incidence of 40.4%. Compared with the HIV-negative individual group of patients had a significantly higher proportion of splenomegaly (13.5% vs. 7.7%; p < 0.01), lymphadenopathy (2.0% vs. 1.3%; p < 0.70), and renal abnormalities (8.4% vs. 3.8%; p < 0.02). There were no differences in hepatic and pancreatic abnormalities between the HIV+ and HIV- groups. There were significantly fewer gallstones in the HIV+ group (1.4% vs. 5.1%; p < 0.01). Conclusion:AIDS is a multi-systemic disease and its demographic and clinical pattern remains the same globally. Ultrasond optimally suited for its clinical management especially in Africa. Its accuracy and sensitivity may be much improved with clinico-pathologic correlation which may not be readily available in developing countries; further studies may provide much needed diagnostic algorithms. "
Accidental ingestion of a drawing pin a case of an unusal foreign body in the Oesphagus
(2001) Agunloye, A. M.; Atalabi, O. M.; Obajimi, M. O.
Baseline chest radiograhic features among antiretroviral therapy naïve human immuno-deficiency virus positive children in a pediatric care program
(2012-01-12) Atalabi, O. M; Oladokun, R.; Adedokun, B,; Obajimi, M. O.; Osinusi, K.
Background: Pulmonary diseases are commonly seen in children with HIV infection, and their etiology is often unclear. The radiological appearances of these conditions are often non-specific. Conventional radiographs play an important role in the management of chest conditions especially in resource poor settings. Objective: This retrospective study was carried out to determine the chest radiographic pattern in children with HIV infection. Materials and Methods: The baseline chest X-ray of 150 HIV-positive but antiretroviral drug naïve children were analyzed between July 2008 and December 2009 at the University College Hospital in Ibadan, south-west Nigeria. All children were screened for tuberculosis (TB) by one or combination of mantoux, acid-fast Bacilli (AFB) sputum, and erythrocyte sedimentation rate. The CD4 count was also taken as part of baseline laboratory test. Chi-squared test was used to determine association between the pattern of chest X-ray findings, and sex, age, and CD4 counts. Results: The mean age of the study group was 51.6 months, with children older than 5 years dominating and there was no statistical difference in the sex distribution. A total of 115 children (76.7%) had abnormal chest X-ray, with lymphadenopathy accounting for 45.3% followed by parenchymal lesions with 37.3%, miliary shadows, and cavities accounted for 6.7% and 2.6%, respectively. Cavities were found to be common in patient who tested positive to AFB than AFB-negative patients. Other findings like reticulonodular or diffuse patterns, lymphadenopathy, pleural effusion, or soft tissue swelling were also commoner in the AFB-positive patients. The CD4 count was available for 42% of the patient and there was no significant association between the chest radiographic changes and the CD4 count. Conclusion: Definitive diagnosis of pulmonary disease might be difficult based on chest X-ray alone, however, chest X-ray is a basic radiological test and almost the easiest to perform in both resource poor or rich setting and it is still recommended that routine chest X-ray should remain part of investigation of HIV-positive children to serve as adjunct to other investigations in early detection of TB.
Bilateral congenital cystic adenomatiod malformation of the lungs: a case report
(2006) Atalabi, O. M; Ogunseyinde, A. O.; Obajimi, M. O.; Falade, A. G.; Adebo, A. O.; Jite, I. E.
A six weeks old infant presented with scalp ulcer and fever, and on examination was found to have resonant percussion notes bilaterally. The initial chest radiograph revealed multiple lucencies which were initially thought to be due to diaphragmatic hernia, but the dilemma was resolved by Computerized tomography which revealed the lucencies to be multiple cysts characteristics of Congenital Cystic Aaenomatiod Malformation (CCAM) type II.
Bl-RADS lexicon: An urgent call for the standardization of breast ultrasound in Nigeria
(Association of Resident Doctors, University College Hospital, 2005) Obajimi, M. O.; Akute, O. O.; Afolabi, A. O.; Adenipekun, A. A.; Oluwasola, A. O.; Akang, E. E. U.; Joel, R. U.; Adeniji-Sofoluwe, A. T. S.; Olopade, F.; Newstead, G.; Schmutz, R.; Sennett, C.
Ultrasound technology and its ability to demonstrate breast anatomy and pathology has changed dramatically and rapidly in the last decade, sonography is now utilized to characterize and manage palpable and mammographic abnormalities. It is also useful in evaluating nipple discharge and mammary implants. Breast ultrasound (BUS) is on invaluable tool for assessing the extent of malignant disease and regional lymph nodes is also available for evaluation of the breast after breast cancer treatment. All of the above have encouraged the development of Bl-RADS ultrasound to further improve and standardize Breast Sonography. This Lexicon is being presented to radiologists, breast surgeons, breast oncologists, breast pathologists, and breast sonographers.
Dermatofibroma of the foot mimicking neurofibroma radiologically
(2006) Agunloye, A. M.; Atalabi, O. M.; Obajimi, M. O.; Adeyinka, A. O.
Diagnostic accuracy of tru-cut biopsy of breast lumps at University College Hospital, Ibadan
(College of Medicine, University of Ibadan and University College Hospital, Ibadan, Nigeria, 2015) Oluwasola, A. G.; Adeoye, A. O.; Afolabi, A. O.; Adeniji-Sofoluwe, A. T. S.; Salami, A.; Ajani, M. A.; Ogundiran, T. O.; Obajimi, M. O.
Background: Tru-cut needle biopsies form an integral part of Triple assessment of breast cancer and include clinical assessment, mammography and core needle biopsy. No study has been done to evaluate the validity of the procedure in our environment. This study was done to evaluate the validity of core needle biopsies in our centre. Method: A retrospective study of patients with tru-cut needle biopsies of breast lumps and follow-up excisional biopsy or mastectomy done in the Department of Surgery, University College Hospital, Ibadan over a ten year period was done. Fifty one patients who fulfilled the inclusion criteria had their records obtained from the Department of Pathology. The diagnosis was classified into benign and malignant with the excisional biopsy or mastectomy diagnosis used as the gold standard. The sensitivity, specificity and accuracy were calculated and kappa was also done to evaluate the degree of agreement. Results: A total of 51 cases were included in this study. The average age of the patients was 47 ± 13 years with a range from 19 to 81 years. Thirty of the biopsies (59%) had a definitive diagnosis of malignancy while twenty one (41%) were benign. The overall sensitivity, specificity and accuracy were 86%, 71% and 80.4% respectively. The specificity of malignant biopsies was 68% while benign was 35%. The level of agreement for malignant biopsies was higher than benign biopsies with a kappa of 0.39 for malignant diagnosis as against 0.29 for benign. Conclusion: Tru-cut needle biopsies have a comparable sensitivity and specificity to excisional biopsies. Diagnostic accuracy can be further enhanced with the adoption of image guided biopsies.
Diagnostic accuracy of tru-cut biopsy of breast lumps at University College Hospital, Ibadan
(College of Medicine, University of Ibadan and University College Hospital, Ibadan, Nigeria, 2015) Oluwasola, A. G.; Adeoye, A. O.; Afolabi, A. O.; Adeniji-Sofoluwe, A. T. S.; Salami, A.; Ajani, M. A.; Ogundiran, T. O.; Obajimi, M. O.
Background: Tru-cut needle biopsies form an integral part of Triple assessment of breast cancer and include clinical assessment, mammography and core needle biopsy. No study has been done to evaluate the validity of the procedure in our environment. This study was done to evaluate the validity of core needle biopsies in our centre. Method: A retrospective study of patients with tru-cut needle biopsies of breast lumps and follow-up excisional biopsy or mastectomy done in the Department of Surgery, University College Hospital, Ibadan over a ten year period was done. Fifty one patients who fulfilled the inclusion criteria had their records obtained from the Department of Pathology. The diagnosis was classified into benign and malignant with the excisional biopsy or mastectomy diagnosis used as the gold standard. The sensitivity, specificity and accuracy were calculated and kappa was also done to evaluate the degree of agreement. Results: A total of 51 cases were included in this study. The average age of the patients was 47 ± 13 years with a range from 19 to 81 years. Thirty of the biopsies (59%) had a definitive diagnosis of malignancy while twenty one (41%) were benign. The overall sensitivity, specificity and accuracy were 86%, 71% and 80.4% respectively. The specificity of malignant biopsies was 68% while benign was 35%. The level of agreement for malignant biopsies was higher than benign biopsies with a kappa of 0.39 for malignant diagnosis as against 0.29 for benign. Conclusion: Tru-cut needle biopsies have a comparable sensitivity and specificity to excisional biopsies. Diagnostic accuracy can be further enhanced with the adoption of image guided biopsies.
Diagnostic accuracy of tru-cut biopsy of breast lumps at University College Hospital, Ibadan
(College of Medicine, University of Ibadan and University College Hospital, Ibadan, Nigeria, 2015) Oluwasola, A. G.; Adeoye, A. O.; Afolabi, A. O.; Adeniji-Sofoluwe, A. T. S.; Salami, A.; Ajani, M. A.; Ogundiran, T. O.; Obajimi, M. O.
Background: Tru-cut needle biopsies form an integral part of Triple assessment of breast cancer and include clinical assessment, mammography and core needle biopsy. No study has been done to evaluate the validity of the procedure in our environment. This study was done to evaluate the validity of core needle biopsies in our centre. Method: A retrospective study of patients with tru-cut needle biopsies of breast lumps and follow-up excisional biopsy or mastectomy done in the Department of Surgery, University College Hospital, Ibadan over a ten year period was done. Fifty one patients who fulfilled the inclusion criteria had their records obtained from the Department of Pathology. The diagnosis was classified into benign and malignant with the excisional biopsy or mastectomy diagnosis used as the gold standard. The sensitivity, specificity and accuracy were calculated and kappa was also done to evaluate the degree of agreement. Results: A total of 51 cases were included in this study. The average age of the patients was 47 ± 13 years with a range from 19 to 81 years. Thirty of the biopsies (59%) had a definitive diagnosis of malignancy while twenty one (41%) were benign. The overall sensitivity, specificity and accuracy were 86%, 71% and 80.4% respectively. The specificity of malignant biopsies was 68% while benign was 35%. The level of agreement for malignant biopsies was higher than benign biopsies with a kappa of 0.39 for malignant diagnosis as against 0.29 for benign. Conclusion: Tru-cut needle biopsies have a comparable sensitivity and specificity to excisional biopsies. Diagnostic accuracy can be further enhanced with the adoption of image guided biopsies.
Malignant haemangiopericytoma of the left thigh with metastases to the bones and lungs: A case report
(2006) Atalabi, O. M; Ibinaiye, O. P.; Obajimi, M. O.; Ogunseyinde, O.; Akang, E. E. U.
Haemangiopericytoma is an uncommon mesenchymal neoplasm. Haemangiopericytoma is believed to arise from the pericytes, contractile spindle cells that surround the capillaries and post-capillary venules. We present an unusal case of histologically confirmed malignant haemangiopericytoma of the thigh in a 70 year old male with metastasis to the lungs and left femoral bone.