Browsing by Author "Ogbole, G. I."

Now showing 1 - 6 of 6

Abdominal ultrasonography inHIV/AIDS patients in southwestern Nigeria.
(BioMEd Central Limited, 2008) Obajimi, M. O.; Atalabi, M. O.; Ogbole, G. I.; Adeniji-Sofoluwe, A. T.; Agunloye, A. M.; Adekanmi, A. J.
"Though the major target of the HIV-virus is the immune system, the frequency of abdominal disorders in HIV/AIDS patients has been reported to be second only to pulmonary disease. These abdominal manifestations may be on the increase as the use of antlretroviral therapy has increased life expectancy and improved quality of life. Ultrasonography is an easy to perform, non invasive, inexpensive and safe imaging technique that is invaluable in Africa where AIDS is most prevalent and where sophisticated diagnostic tools are not readily available. Purpose: To describe the findings and evaluate the clinical utility of abdominal uitrasonography in HIV?AIDS patients in Ibadan. Methods:A Prospective evaluation of the abdominal ultrasonography of 391 HIV-positive patients as well as 391 age and sex- matched HIV-negative patients were carried out at the University College Hospital, Ibadan.Results: Of the 391 cases studied, 260 (66.5%) were females; the mean age was 38.02 years, (range 15-66 years). The disease was most prevalent in the 4th decade with an incidence of 40.4%. Compared with the HIV-negative individual group of patients had a significantly higher proportion of splenomegaly (13.5% vs. 7.7%; p < 0.01), lymphadenopathy (2.0% vs. 1.3%; p < 0.70), and renal abnormalities (8.4% vs. 3.8%; p < 0.02). There were no differences in hepatic and pancreatic abnormalities between the HIV+ and HIV- groups. There were significantly fewer gallstones in the HIV+ group (1.4% vs. 5.1%; p < 0.01). Conclusion:AIDS is a multi-systemic disease and its demographic and clinical pattern remains the same globally. Ultrasond optimally suited for its clinical management especially in Africa. Its accuracy and sensitivity may be much improved with clinico-pathologic correlation which may not be readily available in developing countries; further studies may provide much needed diagnostic algorithms. "
Congenital anomalies in Ibadan, Nigeria
(Spectrum Books. Publisher, Ibadan Nigeria, 2016) Ayede, A. I.; Adeleye, A. O.; Olusanya, A. A.; Ademola, A. D.; Olayemi, O.; Ogbole, G. I.; Akinmoladun, J. A.; Agunloye, A. M.; Akinrinoye, O. O.; Takure, A. O.; Oyewole, O. B.; Oluwatosin, O. M.; Omokhodion, S. I.
Background: There is a need for a multidisciplinary database that can be used as a potential source for developing a protocol and a guideline for a possible nationwide prospective surveillance of congenital anomalies in Nigeria. Methods: This five-year cross-sectional retrospective survey of data from January 2009 to December 2013 was done at the University College Hospital, Ibadan. Data were collected from the admission records on the wards in 8 specialty units with the most workable documented clinical records of congenital anomalies in their care using a predesigned proforma. Proportions of congenital anomalies were determined based on systemic classification of the anomalies and the descriptive terms used were according to the ICD_10-chapter XVIII_RCPCH extension. Result: The total number of patients with congenital anomalies whose records were obtained from the ward registers was 1311, there were 75 (5.7%) missing case notes while information was obtained on 1236 (94.3%) patients. There were a total of 1479 anomalies with multiple anomalies seen in 16.1% of the patients. The male/female ratio was 2:1 and multiple births as well as positive family history of birth defects were seen in about 2.4% and 2.2% of cases respectively. Prenatal diagnosis of the anomalies was documented in only 11 cases (0.9%). Only about one in five cases presented within the neonatal period, and defects of the abdominal wall as well as the cranial-facial-orbital regions were the most prevalent. Next were those in the cardiovascular, spinal column, anorectal and genital, as well as musculoskeletal systems. Conclusion: The size and pan-systemic profiles of the birth defects documented in this study calls for further action on this all-important cause of childhood mortality and significant life-long morbidity in our country.
Phenotyping stroke in Sub-Saharan Africa: stroke investigative research and education network (SIREN) phenomics protocol
(Karger Publishers, 2015) Akpalu, A.; Sarfo, F. S.; Ovbiagele, B.; Akinyemi, R.; Gebregziabher, M.; Obiako, R.; Owolabi, L.; Sagoe, K.; Jenkins, C.; Arulogun, O.; Adamu, S.; Appiah, L. T.; Adadey, M. A.; Agyekum, F.; Quansah, J. A.; Mensah, Y. B.; Adeoye, A. M.; Singh, A.; Tosin, A. O.; Ohifemen, O.; Sani, A. A.; Tabi-Ajayi, E.; Phillip, I. O.; Isah, S. Y.; Tabari, N. A.; Mande, A.; Agunloye, A. M.; Ogbole, G. I.; Akinyemi, J. O.; Akpa, O. M.; Laryea, R.; Melikam, S. E.; Adinku, D.; Uvere, E.; Burkett, N.-S.; Adekunle, G. F.; Kehinde, S. I.; Azuh, P. C.; Dambatta, A. H.; Ishaq, N. A.; Arnett, D.
Background: As the second leading cause of death and the leading cause of adult-onset disability, stroke is a major public health concern particularly pertinent in Sub-Saharan Africa (SSA), where nearly 80% of all global stroke mortalities occur, and stroke burden is projected to increase in the coming decades. However, traditional and emerging risk factors for stroke in SSA have not been well characterized, thus limiting efforts at curbing its devastating toll. The Stroke Investigative Research and Education Network (SIREN) project is aimed at comprehensively evaluating the key environmental and genomic risk factors for stroke (and its subtypes) in SSA while simultaneously building capacities in phenomics, biobanking, genomics, biostatistics, and bioinformatics for brain research. Methods: SIREN is a transnational, multicentre, hospital and community-based study involving 3,000 cases and 3,000 controls recruited from 8 sites in Ghana and Nigeria. Cases will be hospital-based patients with first stroke within 10 days of onset in whom neurovascular imaging will be performed. Etiological and topographical stroke sub types will be documented for all cases. Controls will be hospital- and community-based participants, matched to cases on the basis of gender, ethnicity, and age (±5 years). Information will be collected on known and proposed emerging risk factors for stroke. Study Significance: SIREN is the largest study of stroke in Africa to date. It is anticipated that it will shed light on the phenotypic characteristics and risk factors of stroke and ultimately provide evidence base for strategic interventions to curtail the burgeoning burden of stroke on the sub-continent.
Role of transcranial colour-coded duplex sonography in stroke management
(West Africa Medical Ultrasound Society, 2015) Olatunji, R. B.; Ogbole, G. I.; Atalabi, O. M.; Adeyinka, A. O.; Lagunju, I.; Oyinlade, A.; Ogun, O.; Owolabi, M.O.; Ogunseyinde, O. A.; Ogunniyi, A.
The development of transcranial colour-coded duplex sonography (TCCS) has resurrected the hope of safe, real time bedside brain imaging beyound childhood. This review article provides an overview of the role of TCCS in the management of patients with stroke. The objective is to stimulate interest in the field of neurosomology as a potential means of improving neurological outcome for stroke patients and a area for stroke research endeavours in Africa. Literature search was done on MEDLINE, Cochrane library, and GoogleScholar database with the following keywords: transcranial colour Doppler, Transcranial duplex sonography,stroke, infarct and haemorrhage. We also identified relevant articles from the references section of studies produced by our literature search. We discussed the roles of TCCS to discriminate ischaemic from haemorrhagic forms; unravel the mechanism of stroke; monitor temporal evolution of stroke and predictors of stroke outcome; and promote better understanding of the epidemiology of stroke. It emerging role as a potent point-of-care imaginf modality for definitive treatment in ischaenic stroke within and outside the hospital setting is also highlighted. Comparison of TCCS with alternative modalities for neuroimaging for stroke patients in Africa is presented vis-a-vis the potential economic relief which widespread adoptionof TCCS may provide. We advocate capacity building for TCCS and suggest some action plans required to achieve safe, cheap, affordable and reliable ultrasound based neuroimaging for stroke patients in resource limited areas of Africa.
Routine prenatal ultrasound anomaly screening program in a Nigerian university hospital: redefining obstetrics practice in a developing African country
(2015-08) Akinmoladun, J. A.; Ogbole, G. I.; Lawal, T. A.; Adesina, O. A.
Background: Congenital anomalies are among the leading causes of fetal and infant morbidity and mortality worldwide. Prenatal ultrasound (US) screening has become an essential part of antenatal care in the developed world. Such practice is just evolving in die developing countries such as Nigeria. The aim of this article is to present our initial experience and demonstrate the effectiveness of a prenatal US screening program in detecting congenital malformation in a developing country. Materials and Methods: This was a prospective evaluation of the prenatal .US screenings conducted at a major referral hospital in Southwestern Nigeria All pregnant women referred to the antenatal clinic for mid-trimester screening during the period of study were assessed. Results: Two hundred and eighty-seven pregnant women (5 with twin gestations) were presented for fetal anomaly scan during the study period. Twenty-nine anomalies (9.9%) were detected among the scanned population. Sixteen of the anomalies were followed to delivery/termination with a specificity of 93.5%. The commonest malformations were demonstrated in the genitourinary tract (34.5%) followed by malformations within the central nervous system (27.6%). Six (20.6%) of the anomalies were lethal. Five of the anomalies were surgically collectable. Conclusion: Institutions and hospitals across Nigeria and other low- and middle-income countries need to develop policies and programs that would incorporate a standardized routine screening prenatal US in order to improve feto-maternal well-being and reduce the high perinatal mortality and morbidity in developing nations.
Use of seatbelts by vehicle occupants in University College Hospital, (U.C.H) Ibadan, Nigeria
(Association of Resident Doctors (ARD), University College Hospital (UCH), Ibadan, Nigeria., 2005) Sangowawa, A. O.; Ekanem, S. E. U.; Alagh, B. T.; Ebong, I. P.; Faseru, B.; Uchendu, O.; Adekunle, B. J.; Shaahu, V. H. S.; Fajola, A.; Ogbole, G. I.
Road traffic accidents are a major cause of death and disability worldwide. A number of mecha nisms have been put in place to reduce the ensu ing injuries, one of which is the use of seatbelts. This observational study was carried out to de termine seatbelt use by vehicle occupants in Uni versity College Hospital (U.C.H). Trained re search assistants observed drivers and other ve hicle occupants as they drove into the only fuel station within the hospital premises between 8.30a.m and 6.00 p.m. over a six-day period. Data on vehicle occupant characteristics, pres ence and use of installed seat belts was docu mented using a modified version of the FIA foun dation sample seatbelt wearing observation form. A total of 570 occupants in 402 vehicles were observed. There were 402 drivers and 117 and 50 front and rear seat occupants respectively. The only child observed was unrestrained and seated on an adults lap in the front. Seat belt use by the drivers, front and rear seat passengers were 76 (18.9%), 16 (13.7%) and 2 (4%) respectively. A higher proportion 29 (29.9%) of all female drivers compared with male drivers 47 (15.4%) were restrained (X2 = 9.152, p = 0.02). Overall seat belt use observed was 16.5% and driver use was only 18.9% in spite of the existence of a law mandating use of seatbelt by drivers. Better enforcement of the current law is necessary and it should be extended to cover other vehicle occupants. The hospital environment presents a good opportunity to edu cate the public on the importance of seatbelt use utilizing various health education methods.