Browsing by Author "Ogbole, G. I."

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Abdominal ultrasonography inHIV/AIDS patients in southwestern Nigeria.
(BioMEd Central Limited, 2008) Obajimi, M. O.; Atalabi, M. O.; Ogbole, G. I.; Adeniji-Sofoluwe, A. T.; Agunloye, A. M.; Adekanmi, A. J.
"Though the major target of the HIV-virus is the immune system, the frequency of abdominal disorders in HIV/AIDS patients has been reported to be second only to pulmonary disease. These abdominal manifestations may be on the increase as the use of antlretroviral therapy has increased life expectancy and improved quality of life. Ultrasonography is an easy to perform, non invasive, inexpensive and safe imaging technique that is invaluable in Africa where AIDS is most prevalent and where sophisticated diagnostic tools are not readily available. Purpose: To describe the findings and evaluate the clinical utility of abdominal uitrasonography in HIV?AIDS patients in Ibadan. Methods:A Prospective evaluation of the abdominal ultrasonography of 391 HIV-positive patients as well as 391 age and sex- matched HIV-negative patients were carried out at the University College Hospital, Ibadan.Results: Of the 391 cases studied, 260 (66.5%) were females; the mean age was 38.02 years, (range 15-66 years). The disease was most prevalent in the 4th decade with an incidence of 40.4%. Compared with the HIV-negative individual group of patients had a significantly higher proportion of splenomegaly (13.5% vs. 7.7%; p < 0.01), lymphadenopathy (2.0% vs. 1.3%; p < 0.70), and renal abnormalities (8.4% vs. 3.8%; p < 0.02). There were no differences in hepatic and pancreatic abnormalities between the HIV+ and HIV- groups. There were significantly fewer gallstones in the HIV+ group (1.4% vs. 5.1%; p < 0.01). Conclusion:AIDS is a multi-systemic disease and its demographic and clinical pattern remains the same globally. Ultrasond optimally suited for its clinical management especially in Africa. Its accuracy and sensitivity may be much improved with clinico-pathologic correlation which may not be readily available in developing countries; further studies may provide much needed diagnostic algorithms. "
Role of transcranial colour-coded duplex sonography in stroke management
(West Africa Medical Ultrasound Society, 2015) Olatunji, R. B.; Ogbole, G. I.; Atalabi, O. M.; Adeyinka, A. O.; Lagunju, I.; Oyinlade, A.; Ogun, O.; Owolabi, M.O.; Ogunseyinde, O. A.; Ogunniyi, A.
The development of transcranial colour-coded duplex sonography (TCCS) has resurrected the hope of safe, real time bedside brain imaging beyound childhood. This review article provides an overview of the role of TCCS in the management of patients with stroke. The objective is to stimulate interest in the field of neurosomology as a potential means of improving neurological outcome for stroke patients and a area for stroke research endeavours in Africa. Literature search was done on MEDLINE, Cochrane library, and GoogleScholar database with the following keywords: transcranial colour Doppler, Transcranial duplex sonography,stroke, infarct and haemorrhage. We also identified relevant articles from the references section of studies produced by our literature search. We discussed the roles of TCCS to discriminate ischaemic from haemorrhagic forms; unravel the mechanism of stroke; monitor temporal evolution of stroke and predictors of stroke outcome; and promote better understanding of the epidemiology of stroke. It emerging role as a potent point-of-care imaginf modality for definitive treatment in ischaenic stroke within and outside the hospital setting is also highlighted. Comparison of TCCS with alternative modalities for neuroimaging for stroke patients in Africa is presented vis-a-vis the potential economic relief which widespread adoptionof TCCS may provide. We advocate capacity building for TCCS and suggest some action plans required to achieve safe, cheap, affordable and reliable ultrasound based neuroimaging for stroke patients in resource limited areas of Africa.
Routine prenatal ultrasound anomaly screening program in a Nigerian university hospital: redefining obstetrics practice in a developing African country
(2015-08) Akinmoladun, J. A.; Ogbole, G. I.; Lawal, T. A.; Adesina, O. A.
Background: Congenital anomalies are among the leading causes of fetal and infant morbidity and mortality worldwide. Prenatal ultrasound (US) screening has become an essential part of antenatal care in the developed world. Such practice is just evolving in die developing countries such as Nigeria. The aim of this article is to present our initial experience and demonstrate the effectiveness of a prenatal US screening program in detecting congenital malformation in a developing country. Materials and Methods: This was a prospective evaluation of the prenatal .US screenings conducted at a major referral hospital in Southwestern Nigeria All pregnant women referred to the antenatal clinic for mid-trimester screening during the period of study were assessed. Results: Two hundred and eighty-seven pregnant women (5 with twin gestations) were presented for fetal anomaly scan during the study period. Twenty-nine anomalies (9.9%) were detected among the scanned population. Sixteen of the anomalies were followed to delivery/termination with a specificity of 93.5%. The commonest malformations were demonstrated in the genitourinary tract (34.5%) followed by malformations within the central nervous system (27.6%). Six (20.6%) of the anomalies were lethal. Five of the anomalies were surgically collectable. Conclusion: Institutions and hospitals across Nigeria and other low- and middle-income countries need to develop policies and programs that would incorporate a standardized routine screening prenatal US in order to improve feto-maternal well-being and reduce the high perinatal mortality and morbidity in developing nations.