Browsing by Author "Omokhodion, S. I."

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Ocular abnormalities in newborn infants needing special care
(1998) Baiyeroju-Agbeja, A.; Omokhodion, S. I.
A prospective study was carried out over a six-month period to determine the pattern and outcome of ocular abnormalities in newborn infants needing special care. All babies at risk of developing retinopathy of prematurity (ROP) were excluded from the study as they were included in a concurrently running ROP study. Twenty-eight of the remaining 84 babies examined were found to have ocular problems. These included retinal haernorrhages which were found in 64 percent of the 28 babies, deeply yellow retinae in 18 percent and retinal oedema in seven percent. Although all the changes encountered resolved by the time the babies were discharged, it is recommended that the eyes of babies admitted into the special care baby unit for whatever reason, should be routinely examined, in order to identify early changes that are amenable to treatment.
Ophthalmic congenital anomalies: spectrum and systemic associations in a Nigerian tertiary hospital
(2017) Olusanya, B. A.; Ayede, A. I.; Adeleye, A. O.; Olusanya, A. A.; Lawal, T. A.; Baiyeroju, A. M.; Ogunkunle, O. O.; Joel-Medewase, V. I.; Adebayo, B. E.; Akinrinoye, O. O.; Ashubu, O. F.; Omokhodion, S. I.
Background: To document the pattern of ophthalmic congenital anomalies and their associated systemic anomalies in Nigeria’s foremost university teaching hospital. Methods: Retrospective cross-sectional study conducted at the University College Hospital, Ibadan from January 2009 to December 2013. Clinic and ward registers of various departments and units in the hospital were reviewed to identify children with any structural abnormality, present at birth, which involved the eye and/or its adnexae. Results: Two hundred and forty eight children with 259 ophthalmic congenital anomalies were studied. The median age was 1.2 years with an interquartile range of 4.6 years. The male to female ratio was 1.27:1. Congenital cataract was found in 109 (44%) patients; 40 (15.4%) children had congenital glaucoma, and whole globe anomalies were observed in 18 (6.9%) children. Eighteen (7.9%) children had a family history of congenital anomalies. Associated systemic congenital anomalies were seen in 32 (12.9%) patients with the most common being cardiovascular anomalies in 13 (5.2%) patients. Children who had congenital cataracts were more likely to have multiple associated systemic anomalies (p<0.005). All the children who had associated cardiovascular anomalies had congenital cataracts (p= 0.001). Conclusion: The commonest ophthalmic congenital anomaly presenting for tertiary care in Ibadan is congenital cataract. Cardiovascular anomalies are the commonest systemic association of ophthalmic congenital anomalies. There is an urgent need for the establishment of a registry for congenital anomalies with effective screening and active surveillance within the Nigerian health system.
Ophthalmic congenital anomalies: spectrum and systemic associations in a Nigerian tertiary hospital
(2017) Olusanya, B. A.; Ayede, A. I.; Adeleye, A. O.; Olusanya, A. A.; Lawal, T. A.; Baiyeroju, A. M.; Ogunkunle, O. O.; Joel-Medewase, V. I.; Adebayo, B. E.; Akinrinoye, O. O.; Ashubu, O. F.; Omokhodion, S. I.
Background: To document the pattern of ophthalmic congenital anomalies and their associated systemic anomalies in Nigeria’s foremost university teaching hospital. Methods: Retrospective cross-sectional study conducted at the University College Hospital, Ibadan from January 2009 to December 2013. Clinic and ward registers of various departments and units in the hospital were reviewed to identify children with any structural abnormality, present at birth, which involved the eye and/or its adnexae. Results: Two hundred and forty eight children with 259 ophthalmic congenital anomalies were studied. The median age was 1.2 years with an interquartile range of 4.6 years. The male to female ratio was 1.27:1. Congenital cataract was found in 109 (44%) patients; 40 (15.4%) children had congenital glaucoma, and whole globe anomalies were observed in 18 (6.9%) children. Eighteen (7.9%) children had a family history of congenital anomalies. Associated systemic congenital anomalies were seen in 32 (12.9%) patients with the most common being cardiovascular anomalies in 13 (5.2%) patients. Children who had congenital cataracts were more likely to have multiple associated systemic anomalies (p<0.005). All the children who had associated cardiovascular anomalies had congenital cataracts (p= 0.001). Conclusion: The commonest ophthalmic congenital anomaly presenting for tertiary care in Ibadan is congenital cataract. Cardiovascular anomalies are the commonest systemic association of ophthalmic congenital anomalies. There is an urgent need for the establishment of a registry for congenital anomalies with effective screening and active surveillance within the Nigerian health system.
Patency of the ductus arteriosus in newborns: experience in a special care baby unit
(2001) Omokhodion, S. I.; Baiyeroju-Agbeja, A. M.; Adegboye, V. O.; Adeyemo, A.; Lagunju, L. A.
A prospective cohort study of infants admitted into the Special Care Baby Unit, University College Hospital, Ibadan, has revealed a 24.5 per cent prevalence of patency of the ductus arteriosus (PDA) among 97 infants, who were admitted over a six-month period. The major factor predisposing to PDA was prematurity (p=0.014). A higher incidence of PDA (35 per cent) Was found among the preterm infants, and of these preterm infants, the very low birth weight (VLB'W') infants were found to be more highly susceptible to PDA (p=0.028). The mean birth weight of the preterm infants who developed PDA in the study was 1447g, while that of those without PDA was 1835g. There was no relationship between the sex of the infants and the development of PDA. A strong association was however, found between respiratory distress and PDA (p<0.0001). Nine of the hospital mortalities recorded occurred in the preterm infants and more than half of them (55.5 percent) had PDA Thus, prematurity is a risk factor for PDA and the presence of a PDA appears to increase the risk for mortality for such infants. Evidence for PDAshould be sought in all premature infants and prompt and aggressive management of those infants who show signs of decompensation from PDA is recommended to reduce mortality from this disease.
Screening for retinopathy of prematurity in Ibadan
(1998-08) Baiyeroju-Agbeja, A.; Omokhodion, S. I.
Between January to June 1995, a prospective study was carried out to determine the incidence and severity of retinopathy of prematurity (ROP) in newborn infants of less than 1,500g birthweight or less than 31 weeks gestational age. 18 babies were eligible for inclusion in this study and only one developed ROP, a Stage 1, Zone III disease i.e. 5.5% of babies at risk. In spite of the low incidence compared with other studies', it is advisable to continue the collaboration between opthalmologists and neonatologists to prevent babies at risk from developing untreatable ROP, thereby increasing the number of blind children in our society.