Browsing by Author "Osman, E."

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Factors associated with treatment success among pulmonary tuberculosis and HIV co-infected patients in Oyo State, South West-Nigeria
(Nigerian Medical Association, Rivers State Branch., 2013) Oladimeji, O. O.; Obasanya, J. O.; Daniel, O. J.; Gidado, M.; Akolo, C.; Oladimeji, K. E.; Atilola, O.; Ajayi, T.; Adeyinka, A. D.; Osman, E.; Odusote, T.; Awe, A.; Lawalu, O.; Omoniyi, A.; Dairo, D. M.; Adedokun, B. O.; Adeoye, I. A.; Igodekwe, F. C.; Hassan, A.; Onoja, M. A.
BACKGROUND The co-existence of Tuberculosis (TB) and Human immunodeficiency Virus (HIV) is known to increase morbidity and mortality in patients. The determinants of treatment success in TB- HIV co-infection are not yet well studied. Such information can help optimise treatment and reduce morbidity and mortality. OBJECTIVE To determine factors associated with anti- tubercular treatment success among TB /HIV coinfected patients. METHODS A cross sectional study was carried out in fifty three DOT clinics and treatment centres using tuberculosis patient’s records from January 2009 to December 2010 in Oyo state, Nigeria. The study population consisted of 7905 tuberculosis patients. Information on variables of interest were obtained with the use of data extraction forms. Chi-square and logistic regression were used to test the relationship between TB/ HIV co- infection and socio-demographic variables, clinical characteristics and treatment success. RESULTS Prevalence of TB /HIV co-infection was found to be 14.2%. Patients with TB-HIV co-infection were younger and more likely to be females. There were statistically significant association between treatment success and gender, marital status and patient point of care. After adjusting for other variables, it was found that patients receiving treatment in private facilities were independently less likely to be successfully treated compared with those receiving care in Public facilities. Female patients were also independently more likely to have better treatment outcome than male. CONCLUSION In addition to patients’ point of care, gender of the patients can adversely impact on their treatment success. Efforts from the government to strengthening the private public mix, health education and media awareness on adherence to treatment to improve treatment success should be intensified in the country.
Prevalence of previously undetected tuberculosis and underlying risk factors for transmission in a prison setting in Ibadan, southwestern Nigeria
(University College Hospital (UCH), Ibadan., 2014) Adesokan, H. K.; Cadmus, E.O.; Adeyemi, W. B.; Lawal, O.; Ogunlade, C.O.; Osman, E.; Olaleye, O.D.; Cadmus, S.I.B.
People with congregational tendencies such as the prison inmates constitute an important target group in the global efforts towards the control of tuberculosis (TB). The prison setting in most developing countries particularly Nigeria, currently does not have routine diagnostic procedures for TB despite the existing risks that could facilitate disease transmission. We conducted a cross sectional study among the inmates in a major prison in south-western Nigeria for TB by screening their sputum samples using a simple random sampling method coupled with questionnaire interview, on the assumption of sub-clinical pulmonary TB infection. The overall TB prevalence found was 1.2% (2/164). Significant risk factors that could facilitate disease transmission in the prison included lack of BCG immunization (p = 0.017); history of contact with TB patients (p = 0.020); prolonged cough (p = 0.016) and drug abuse (p = 0.019). Our findings of 1.2% undetected pulmonary TB infection among the inmates though low; still reiterate previous observation that the prison setting constitutes a veritable environment for TB transmission and a threat to public health. Efforts are therefore needed to institute routine screening and reduce the risk factors associated with TB transmission among prison inmates in Nigeria.