Browsing by Author "Titiloye, M."

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    Statistical modeling of social risk factors for sexually transmitted diseases among female youths in Nigeria
    (Open Learning on Enteric Pathogens, 2013) Adebowale, A. S.; Titiloye, M.; Fagbamigbe, A. F.; Akinyemi, O. J.
    Introduction: Sexually transmitted diseases (STDs) are preventable, but the social risks factors connected to them are often not understood, particularly by female youths. There has been a dearth of information on the identification of social risk factors influencing STDs among female youths in Nigeria, hence we conducted this study. Methodology: This retrospective cross-sectional study utilized the Nigeria Demographic and Health Survey, 2008. It focused on female youths aged 15-24 (n=7,736) who ever had sexual intercourse. Data was analyzed using Chi-square and logistic regression models. Results: The mean age of the respondents was 20.2±2.5years. More female youths aged between 20 and 24 years contracted STDs in the last 12 months (2.5%) than those between the ages of 15 and 19 months (1.4%). A year prevalence of STDs among female youths in Nigeria was 2.1%. Socio-demographic factors such as age, education, wealth index, marital status, shared toilet, residence, contraceptive use, and total life-time number of sexual partners were found to be associated risk factors for contracting STDs (p<0.05). Controlling for potential confounding variables at the fifth iteration, the identified predictors of contracting STDs were wealth index, total lifetime number of sexual partners, awareness of HIV/AIDS, and shared toilet facility (p<0.05). Conclusions: The data confirmed the considerable impact of wealth index and awareness of HIV/AIDS as important predictors of STDs acquisition. Providing free condoms, along with teaching the importance of abstinence and improving knowledge of HIV/AIDS, can help to reduce the risk of STDs transmission.
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    Unraveling the ethical, legal, and social implications of neurobiobanking and stroke genomic research in Africa: a studyprotocol of the African neurobiobankfor precision stroke medicine ELSI project
    (Sage Publications, 2020) Akinyemi, R. O.; Jenkins, C.; Nichols, M.; Singh, A.; Wahab, K.; Akpalu, A.; Sarfo, F. S.; Owolabi, L. F.; Obiako, R.; Akinyemi, J.; Ojebuyi, B.; Adigun, M.; Musbahu, R.; Bello, A.; Titiloye, M.; Calys-Tagoe, B.; Ogunronbi, M.; Uvere, E.; Laryea, R.; Fakunle, A.; Adeleye, O.; Olorunsogbon, O.; Ojo, A.; Adesina, D.; Mensah, N.; Oguike, W.; Coleman, N.; Mande, A.; Uthman, M.; Kalaria, R. N.; Jegede, A.; Owolabi, M.; Ovbiagele, B.; Arulogun, O.
    The ethical, legal, and social implications (ELSI) of emerging neurobiobanks and data resources are unclear in an African scientific landscape with unique cultural, linguistic, and belief systems. The overarching goal of the African Neurobiobank for Precision Stroke Medicine–—ELSI Project is to identify, examine, and develop novel approaches to address ELSI issues of biobanking and stroke genomic research in sub-Saharan Africa (SSA). To accomplish the goal we will (1) explore knowledge, attitude, perceptions, barriers, and facilitators influencing ELSI issues related to biobanking and stroke genomic research; (2) use information obtained to craft a community intervention program focused on ELSI issues; and (3) build capacity and careers related to genomics and biobanking for effective client/community engagement while enhancing regulatory, governance, and implementation competences in biobanking science in SSA. A community-based participatory research and mixed-methodological approach, focused on various levels of the social ecological model, will be used to identify and examine relevant ELSI issues. Contextual intervention tools, platforms, and practices will be developed to enhance community understanding and participation in stroke biobanking and genomics research activities while facilitating enduring trust, and equitable and fair utilization of biobanking resources for genetic and trans-omics research. A concurrent capacity building program related to genetic counseling and biobanking will be implemented for early career researchers. The huge potential for neurobiobanking and genomics research in Africa to advance precision medicine applicable to stroke and other neurological disorders requires addressing ELSI challenges while building sustainable research, career, and regulatory capacities in trans-omics and biobanking science.