Browsing by Author "Umotok, N. E."

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    Foliar epidermal morphology and anti-diabetic property of andrographis paniculata(burm.f.) wall ex nees
    (2010) Fasola, T. R.; Ayodele, A. E.; Odetola A. A.; Umotok, N. E.
    The leaf epidermal features and anti diabetic property of Androgragphis paniculata were investigated. The epidermal cells are polygonal to irregular with curved to undulate anticlinal walls on both surfaces of the leaf. The leaf is hypostomatic with stomata restricted to the abaxial surface. Stomata type is axillocytic. The epidermal cells contain deposits of crystal oxalates while cystoliths are found in a few cells. The leaf extract was evaluated for hypoglycemic effects. There was significant hypoglycemic effect in alloxan induced diabetic rats following administration of the leaf aqueous extract. The result shows that the level of fasting blood sugar was dependent on the previous level of basal blood sugar in the four groups of rats used for this study. Treatment of the rats with A. paniculata showed a dose dependent relationship with the time it took for the blood of the rats to return to the basal blood sugar levels. The study supports the use of the plant in the management and treatment of diabetes.