Browsing by Author "Yahaya, M."

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Genetic analysis of agronomic and fall armyworm-resistance traits in maize hybrids with varying levels of resistance to stem borers
(Multidisciplinary Digital Publishing Institute (MDPI), 2022) Job, A.; Iseghohi, I.; Abe, A.; Yahaya, M.; Olayiwola, R.; Akinwale, R.; Obisesan, O.; Igyuve, M.
Stem borer (SB) and more recently, fall armyworm (FAW) are serious economic pests in maize production in sub-Saharan Africa. It is hypothesized that SB-resistant germplasm may confer resistance against FAW. However, the performance of SB-resistant lines in hybrid combinations and the inheritance of FAW-resistant traits under variable FAW infestations have not been reported. This study was conducted to (i) obtain information on the inheritance of agronomic and FAW-resistant traits under variable FAW infestations; (ii) identify hybrids combining high grain yield (GYLD) and stability under FAW infestations; and (iii) determine the effects of FAW damage on GYLD. Three SB-resistant lines (1393, CKSBL10060 and CML 331) as testers and six open-pollinated varieties (OPVs) as lines were crossed in a line tester scheme to generate eighteen test crosses. The test crosses together with two tester x tester crosses and two checks were evaluated under artificial FAW infestation (AI), natural infestation (NI) and pesticide-protected condition (PC) in Nigeria. Additive and nonadditive effects were significant for GYLD, most agronomic and FAW-resistant traits under AI and NI, except ear damage (EDAM) scores under NI, whereas only the non-additive effect was significant for GYLD under PC. Two testers (1393 and CKSBL10060) combined significant and positive GCA effects for GYLD with desirable GCA effects for FAW-resistant traits under AI and NI, whereas CML 331 combined significant and negative GCA effects of GYLD with undesirable GCA effects of FAW resistance under the test conditions. Three OPVs (AWR SYN-W2, AMATZBR-WC4 and TZB-SR) had a significantly positive GCA effect for GYLD and a desirable GCA effect for either leaf damage (LDAM) or EDAM score under AI. The FAW LDAM and EDAM significantly reduced GYLD under AI but not under NI. Three test crosses (AMATZBR-WC4 x CKSBL10060, TZB-SR x CKSBL10060 and TZBR Comp 1-WC2 x 1393) combined high yield with stability and FAW tolerance across the test conditions and thus were recommended for further testing.
Human Papillomavirus (HPV) Infection in Males: A Need for More Awareness
(IntechOpen Press, 2019) Manga, M. M.; Fowotade, A.; Yahaya, M.
Globally, human papillomavirus (HPV) is the most common viral sexually transmitted pathogen, which is significantly associated with high morbidity and mortality in both sexes. Except those vaccinated, virtually all sexually active individuals will be infected with HPV in their lifetime. Although most HPV infections are transient, association with anogenital warts, cervical, penile, and other malignancies have been reported. HPV can be transmitted from one person to another through contact especially during sexual contact including anal, vaginal, or oral. Although HPV infection affects both males and females, its causal association with cervical cancer has made most literature to be mainly on females. In view of its sexual transmissibility and the increasing prevalence of HPV-related malignancies among males worldwide, there is need for more awareness on the infection in males. Most developed countries offer HPV vaccination for girls, but vaccine recommendations for boys are still relatively uncommon especially in developing countries where the burden of HPVrelated malignancies is still very high. The current discourse highlights the need for increased awareness on HPV vaccination among this neglected gender group.
Serosurvey of human T cell lymphotropic virus I/II among blood donors in Gombe (Nigeria)
(EDORIUM Journals, 2016) Manga, M. M.; Fowotade, A.; Yuguda, S.; Iya, G. A.; Yahaya, M.; Sheriff, Y. M.; Omoruyi, E. C.; Yola, I. M.; Bakare, R. A.
Aim: This study was carried out to determine the prevalence of human T cell lymphotropic virus I/II (HTLV I/II) among blood donors at the Federal Teaching Hospital Gombe (FTHG), North-eastern, Nigeria. Methods: A total of 355 blood donors were recruited at the hematology department of FTHG for a hospital based crosssectional study and were screened/confirmed for HTLV I/II by ELISA and western blot methods. Results: Seroprevalence of HTLV I/II among the 355 participants with mean age of 30.77 years (±8.27) was 6.5% on screening with ELISA but confirmed to be 0% by western blot. Majority were males, 352 (99.2%) and mostly (45.9%) between 21–30 years of age. Donors for family replacements predominated (85.1%) with more than half (58.6%) being first time blood donors. Conclusion: This study reveals the absence of HTLV I/II among blood donors in Gombe Northeastern Nigeria. It also highlights the possibility of false positivity in some of the reported prevalence of HTLV I and II from some parts of Nigeria that were based on screening tests only. The importance of confirmatory testing in all research works on HTLV (including HTLV 3 and HTLV 4) is further strengthened with this study. There is however the need for a larger study and the use of molecular diagnostics to reconfirm this assertion.