Browsing by Author "Yakubu, A."
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Item Characterisation of indigenous helmeted guinea fowls in Nigeria for meat and egg production(2021) Shoyombo, A.J.; Yakubu, A.; Adebambo, A. O.N.; Popoola, M. A.; Olafadehan, O. A.; Wheto, M.; Alabi, O. O.; Osaiyuwu, H. O; Ukim, C. I.; Olayanju, A.; Adebambo, O. A.There is increasing interest in sustainable poultry production in developing economies. This review provides an insight into guinea fowl production in Nigeria as a means of additional high-quality poultry meat and egg production. Under the smallholder scavenging system, flock size of the four investigated plumages (Pearl, Lavender, Black and White) of indigenous helmeted guinea fowl in Nigeria typically ranges from 6 to 9 birds per household, 14-week mean live weight from 917 to 975 g, dressed weight at this age from 700 to 737 g and dressing percentage from 74 to 76%. Under the back yard system of production, mean egg number is typically about 80 eggs per hen/annum while under intensive management it can be up to 147 eggs per hen/annum and egg weight from 29 to 38 g. Under smallholder conditions, hatchability of fertile eggs can range from 70 to 86% while under improved housing and rearing conditions it can be as high as 89%. The present information could be exploited in formulating appropriate management strategies and breeding decisions for sustainable production of hybrid improved guinea fowls,thereby contributing to food security in Nigeria.Item Clinicoradiologic and sonographic patterns of metastasis in hepatocellular carcinoma(2006) Otegbayo, J. A.; Atalabi, O. M.; Yakubu, A.Hepatocellular carcinoma(HCC) is usually diagnosed at an advanced stage, when little remedy could be offered. There is a need for relatively affordable, available and non- invasive tests for diagonsis, staging and detection of metastasis among individuals at risk. A clinical, chest radiographic (CXR) and abdominal ultrasonographic examination was carried out to detect and evaluate the pattern of metastasis among 53 untreated patients. One patients had clinical paraparesis with no outward evidence of metastasis. CXR revealed lund metastasis in 11(20.8%), with multifocal deposit in one. Two (3.8%) patients had perihilar lymphadenopathy and consolidation, respectively, while 18 (34%) patients had elevated right hemidiaphragm and four (7.5%) had pleural effusion. One right hemidiaphragm and four (7.5%) had pleural effusion. One had right basal pneumonitis, multiple cavitatory lesions in the lungs fields and soft-tissue wasting. No abnormality was seen in 17 (32.1%) cases. Abdominal ultrasonograph showed probe tenderness in 22(41.5%), hepatomegaly in 49(92.5%), with 33(62.3%) of these having nodularities of varying sizes. The spleen was enlarged in 10(18.9%) cases, with para-aortic lymphadenopathy. Portal hepatic lymphadenopathy was demostrated in two (3.8%) cases, while pleural effusion was detected in seven (13.2%). Metastasis is common in HCC at presentation, the lung is the commonest site of spread. Clinically visible metastasis appears uncommon in HCC.Item Helicobacter pylori serology and evaluation of gastroduodenal disease in Nigerias with dyspepsia(2004) Otegbayo, J. A.; Oluwasola, O. A.; Yakubu, A.; Odaibo, G. N.; Olaleye, O. D.Helicobacter pylori (H. pylori) has been strongly associated with various gastroduodenal diseases worldwide with only a few studies emanating from developing countries. The objectives of this study were to determine the prevalence of serum immunoglobulin G (lgG) and underlying gastroduodenal pathology in Nigerian patients with dyspepsia and ascertain the usefulness of H.pylori lgG screening in decreasing endoscopic workload in dyspeptics in Nigeria. fifty-five patients with dyspepsia and 55 age and sex-matched apparently normal control were screened for H.pylori lgG using ImmunocombrII kits. Each of the 55 patients were also examined endoscopically with biopsies taken appropriately. Serology was positive in 94.5% and 92.7% of dyspeptic patients and controls respectivley. Gastroduodenal inflammation was the commonest endoscopic finding, 43 (78.18%). Other findings were malignant gastric tumour 6(10.9%), reflux oesophagitis 3(5.45%), gastric ulcer 2(3.64%), and duodenal ulcer in 1(1.82%). chronic gastritis was the main histopathologic finding in the dyspeptic patients. It is concluded that serum H. pylori lgG cannot be used as a screening procedure to reduce endoscopic workload in Nigerian patients with dyspepsia.Item Linear Body Measurements Of Grower Rabbits Fed Shea Butter Nut Meal In North Central Nigeria(2016) Idahor, K. O.; Osaiyuwu, O.H.; Yakubu, A.There is a high demand for rabbit either as meat, pet or laboratory animal. However, its production is still at subsistence level in Nigeria. This could be due to the rising competition between man and livestock for conventional feeds tuffs. This study was aimed at investigating the suitability of shea butter nut meal (SBNM as an unconventional fee d stuff in rabbit diets. A total of 36 rabbits weighing about 1.2kg at 7wks old, were fed 0.0% (TJ, 2.0% (TJ and 6.0% (TJ SBNM for eight weeks. The results indicated significant differences (P<0.05) among the treatments. Body weight gain values ranged from 0.03g to 0.26g. The hind limb length varied 'from 0 .1 3 - 0.38cm, hair length (0.07 - 0.16cm) and the chest circumference value varied from 0.1 - 0.33cm. Although, it was observed that the values of growth indices monitored did not follow a definite trend among the treatments. There was an increase in value of all the parameters measured throughout the study period. Thus, SBNM may probably be a suitable feedstuff at 6.0% inclusion in rabbit grower diets.Item Multivariate characterisation of morpho biometric traits of indigenous helmeted Guinea fowl (Numida meleagris) in Nigeria(2022) Yakubu, A.; Jegede, P.; Wheto, M.; Shoyombo, A.J.; Adebambo, A.O.; Popoola, M.A.; Osaiyuwu, O.H.; Olafadehan, O.A.; Alabi, O.O.; Ukim, C.I.; Vincent, S.T.; Mundi, H.L.; Olayanju, A.; Adebambo, O.A.This study was conducted to characterise phenotypically helmeted Guinea fowls in threeagro-ecologies in Nigeria using multivariate approach. Eighteen biometric characters, fou rmorphological indices and eleven qualitative physical traits were investigated in a total of 569 adult birds (158 males and 411 females). Descriptive statistics, non-parametric Krus kal–Wallis H test followed by the Mann–Whitney and Dunn-Bonferroni tests for post hoc, Multiple Correspondence Analysis (MCA), Univariate Analysis, Canonical Discriminant Analysis, Categorical Principal Component Analysis and Decision Trees were employed to discern the effects of agro-ecological zone and sex on the morphostructural parameters. Agro-ecology had significant effect (P<0.05; P<0.01) on all the colour traits. In general, the most frequently observed colour phenotype of Guinea fowl had pearl plumage colour (54.0%), pale red skin colour (94.2%), black shank colour (68.7%), brown eye colour (49.7%), white earlobe colour (54.8%) and brown helmet colour (72.6%). The frequencies of helmet shape and wattle size were significantly influenced (P<0.01) by agro-ecology and sex. Overall, birds from the Southern Guinea Savanna zone had significantly higher values (P<0.05) for most biometric traits compared to their Sudano-Sahelian and Tropical Rainfor est counterparts. They were also more compact (120.00 vs. 110.00 vs. 107.69) but had lesser condition index (7.66 vs. 9.45 vs. 9.30) and lower long-leggedness (19.71 vs. 19.23 vs. 9.51) than their counterparts from the two other zones. Sexual dimorphism (P<0.05) was in favour of male birds especially those in Southern Guinea Savanna and Sudano-Sahelian zones. However, the MCA and discriminant analysis revealed considerable intermingling of the qualitative physical traits, biometric traits and body indices especially between the Sudano-Sahelian and Tropical Rainforest birds. In spite of the high level of genetic admixture, the Guinea fowl populations could to a relative extent be distinguished using wing length, body length and eye colour. Generally, the birds from the three zones appeared to be more homogeneous than heterogeneous in nature. However, further complementary work on genomics will guide future selection and breeding programs geared towards improving the productivity, survival and environmental adaptation of indigenous helmeted Guinea fowls in the tropics.Item Nigeria butchers and hepatitis B virus infection(2008) Ola, S. O.; Otegbayo, J. A.; Yakubu, A.; Odaibo, G. N.; Olaleye, D. O.Various target groups have been identified in Nigeria for studying the prevalence of hepatitis B virus infection; however there is no information on its prevalence among workers in slaughter houses. This study determined the seroprevalence of hepatitis B virus infection in Nigerian butchers at Ibadan, and comprised 360 healthy Nigerian adult subjects (180 butchers, 180 traders as controls) selected by multistage stratified sampling. A questionnaire was used to collect relevant information and included points about risk behaviour. ELISA was used to detect the hepatitis B surface antigen in the serum; the seroprevalence rate in butchers and controls was 9.4% and 3.3%, respectively (p<0.05). Risk behaviour was seen more commonly in butchers than in controls. The presence of hepatitis B surface antigen in the serum was not related to the duration of occupational exposure or the number of partners. In summary, butchers comprise a high-risk occupational group for exposure to hepatitis B virus infection. We conclude that routine screening for parenterally acquired infections in this group is thus necessary in order to identify those who will require treatment and immunisation, especially against hepatitis B virus infection.Item Pitfalls in diagnosis of hepatitis B virus infection among adults Nigerians(2009) Ola, S. O.; Otegbayo, J. A.; Yakubu, A.; Aje, A. O.; Odaibo, G. N.; Shokunbi, W."OBJECTIVE:Hepatitis B virus infection is common in Nigerians and its diagnosis is necessary for effective treatment and eradication. This study is aimed at highlighting the serological factors jeopardizing the diagnosis and treatment of the infection among Nigerians adults. PATIENTS AND METHODS:Three studies were carried out. The first study involved 56 Nigerian adults and it compared the assay of HBsAg by Haemagulation Method (HMA) with Enzyme linked immunoassay (ELISA). The second study was a comparison of Glaxo Welcome HB rapid test(GWHB) with ELISA in sero-assay of HBsAg and HBeAg among 25 Nigerian subjects while the third study was on the assay of the sera of HBsAg positive patients for HBeAg and anti-HBe in forty two Nigerian patients by ELISA. RESULTS:The sero - prevalence rates of HBsAg were 41.8% and 61.8% by HM and ELISA respectively with false HBsAg sero-positives and sero-negatives by HM of 5.4% and 25.5% respectively. Similarly, there was sero-detection of HBsAg in 84% and 80% by ELISA and GWHB respectively in 25 Nigerian adults. In addition, 19% and 64% of the 42 patients with HBsAg sero-positivity were also positive for HBeAg and anti-HBe respectively, while 31% of the patients were both HBeAg and anti-HBe sero-negative. CONCLUSION:Sero-diagnosis of HBsAg and other serological markers of infectivity in patients with HBV should be carried out by ELISA rather than HMA among adult Nigerians. Furthermore, high infectivity of the virus abounds among Nigerian with HBV infection."