Scholarly works in Psychiatry

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    Global neuroAIDS
    (Springer, 2015) Oladeji, B. D.; Yosief, S.; Robertson, K. R.
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    Mental health
    (Cambridge University Press, 2013) Gureje, O.; Oladeji, B.
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    Mental health and HIV in Africa
    (Jones and Bartlett Learning, 2012) Oladeji, B. D.; Gureje, O.
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    Mental disorders and earnings: results from the Nigerian National Survey of Mental Health and Well-Being (NSMHW)
    (International Center of Mental Health Policy and Economics, 2012) Esan, O. B.; Kola, L.; Gureje, O.
    Background: Mental disorders are associated with a loss in earnings both at the individual and societal level. Very few studies have addressed the issue of the cost of mental illness in Sub-Saharan Africa. These studies have been largely hospital based, localized, and have addressed only a few mental disorders using very small sample sizes. Aims of the Study: To examine the impact of mental disorders on earnings of affected persons. Methods: Mental disorders on and personal earnings were assessed in a representative sample of 1,889 Nigerians aged 18-64 years in an epidemiological survey. Version 3.0 of the World Health Organization Composite International Diagnostic Interview (WHO CIDI) was used to assess mental disorders. Respondents were also asked to report their personal earnings before tax in the past 12 months, while authors predicted personal earnings in the same period from information about 12 month and life time DSM IV mental disorders among respondents. Results: A 12-month prevalence of Serious Mental Illness (SMI) was found in 0.5% of the sample while other 12-month disorders had a prevalence of 4.83%. The prevalence of other lifetime disorders was 4.14%. The mean annual impact of serious mental illness was 60,126 Naira (US$ 463). At the level of the society the annual impact was 21.6 billion Naira (US$ 166.2 million). Discussion: Mental disorders have an enormous individual and societal financial burden. This impact appears more severe in males. Implications for Health Care Provision and Use: Mental disorders have enormous negative impacts on earnings both at the individual and societal level. This analysis highlights the financial value of lost earnings in the absence of such disorders. Implications for Health Policies: An increase in spending on mental health based on proportionate economic burden of mental disorders may substantially reduce financial losses due to mental disorders. Implications for Further Research: In the present study, only the indirect health care costs have been assessed. Future research should consider direct costs.
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    A Study of 31 Patients with Primary Complaint of Halitosis in a Tertiary Hospital in South-Western Nigeria.
    (College of Medicine, University of Ibadan, 2019) Adeyemi, B.F.; Esan, O. B.; Akinyamoju, A. O.
    BACKGROUND: Halitosis is a common cause of dental consultation. Patients presenting with primary complaint of halitosis consist of dissatisfied people with genuine and pseudo-halitosis. OBJECTIVES: To assess the demographic and clinico-pathologic features of patients presenting with primary complaint of halitosis as well as evaluate the treatment outcome. METHODS: Consenting patients presenting with primary complaint of halitosis from 1st of March to 31st August, 2015 were recruited. All had intraoral examination, were screened for psychiatric morbidity and halitosis using the organoleptic method. Data concerning the complaint of halitosis was retrieved from all through an interviewer-administered structured questionnaire. All the patients were educated on the aetiology of halitosis, those with oral disease were treated and all had scaling and polishing, oral hygiene instruction/motivation in addition to hydrogen peroxide mouth rinse for two weeks. Patients’ opinions were sought concerning the presence/ intensity of halitosis at two weeks and six months post treatment. RESULTS: Thirty-one patients with a mean age of 38.48 years and male: female ratio of 1.3 were recruited. Intraoral pathology was observed in 48.4% of patients. None of the patients smoked cigarette or pipe. Twenty patients (64.5%) had been informed of the foulness of their breath by at least one person in the past; the information generated negative feelings in 19 of them. Six patients had psychiatric morbidity which was significantly associated with female gender and presence of body odour. At two weeks post treatment, 54.8% of patients were free of halitosis, while at six months only 25.8% were free. CONCLUSION: The patients who complained of halitosis were non-smokers with a mean age of 38.48±14.0 years. Intraoral pathologies were found in fifteen (15) patients, while six (6) had psychiatry morbidity. About half of the patients and about a quarter were free of halitosis following scaling and polishing and two weeks’ hydrogen peroxide mouth rinse at 2 weeks and 6 months’ reviews, respectively.
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    Achieving health security in Nigeria: A strategic blueprint for addressing psychoactive substance use
    (College of Medicine, University of Ibadan, 2019) Abdulmalik, J.O.; Lasebikan, V.O.; Makanjuola, V.A.; Oshiname, F. O.; Oladeji, B. D.; Esan, O. B.; Bella - Awusah, T. T.; Ojagbemi, A. A.; Adeniyi, Y. P.; Gureje, O.; Omigbodun, O. O.
    Introduction: Psychoactive substance use is an important component of health and national security. Nigeria has evolved from a largely transit nation for psychoactive substances to a high consumption nation. Increasing rates of use result in a concurrent rise in crime rates and insecurity, as well as road traffic accidents. The use of psychoactive substances is also implicated in episodes of civil strife, conflicts and wars, such as the ongoing Boko Haram insurgency in North East Nigeria. This observation is likely to worsen over time if there is no coherent and strategic plan to halt and reverse this trend. The forecast portends higher crime rates, heightened insecurity, civil unrest and violent conflicts by 2050, if the rising trend of psychoactive substance use is not reversed. It is a scenario that will not augur well for the stability of Nigeria and the West African region. Methods: A narrative review of the published literature, as well as expert opinion deliberations was utilized to develop a comprehensive analysis of the strategic strengths, weaknesses, opportunities and threats (SWOT) of psychoactive substance use and health security implications for Nigeria. Results: An array of the unique strengths and opportunities are spelt out; along with the inherent weaknesses and threats that should be taken into consideration in mapping out strategies to address the clear and present danger from the rising use of psychoactive substances in Nigeria. Conclusion: Recommended interventions should focus on public awareness campaigns, utilizing behaviour change communication strategies – with a special focus on prevention, mental health promotion activities, training and re-training of regulatory agencies, development and revision of existing policies, as well as better policing and enforcement of access restriction.
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    Optimal mental health for achieving health security in Nigeria: a strategic blueprint
    (College of Medicine, University of Ibadan, 2019) Ojagbemi, A. A.; Abdulmalik, J. O.; Lasebikan, V. O.; Oladeji, B. D.; Makanjuola, V. A.; Esan, O. B.; Bella - Awusah, T. T.; Adeniyi, Y. P.; Gureje, O.; Omigbodun, O.O.
    Objectives: Optimal mental health refers to ‘a state of well-being in which the individual realizes his or her abilities, can cope with the normal stresses of life, can work productively and fruitfully, and is able to make contributions to his or her own community’. As such, the catchphrase ‘No health without mental health’ is not just a slogan but an acknowledgement of the importance of mental health in the drive to improve overall wellbeing and productive participation in community and economic activities. Methods: We combined an overview of current literature with opinions of key experts from different sub specialties of mental health practice and present an analysis of the Strengths, Weaknesses, Opportunities and Threats (SWOT) to optimal mental health as a strategy to attaining health security in Nigeria by 2050. We also offered recommendations for feasible strategies to optimize mental health. Results: There is poor mental health coverage in Nigeria, with over 80% of persons coping with mental health problems remaining untreated in their lifetime. Also, only about 3% of the National health budget is allocated to mental health and this is mostly focused on large psychiatric institutions to the exclusion of primary health care (PHC) services. Conclusions: In recognition of the critical role of optimal mental health to global development, the Sustainable Development Goals (SDGs) has mental health firmly covered in its third goal, ‘Health and Well-being’. The SDGs further envision a better world in which, in tandem with the WHO definition of health, “physical, mental and social wellbeing are assured”. Thus, the identification and implementation of strategies to promote optimal mental health for all Nigerians is vital for ensuring health security and national development.
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    Partnership for mental health development in Sub-Saharan Africa (PaM-D): a collaborative initiative for research and capacity building
    (Cambridge University Press & Assessment, 2019) Gureje, O.; Seedat, S.; Kola, L.; Appiah-Poku, J.; Othieno, C.; Harris, B.; Makanjuola, V.; Price, L.N.; Ayinde, O. O.; Esan, O. B.
    Aims In low and middleincome countries (LMIC) in general and sub-Saharan African (SSA) countries in particular, there is both a large treatment gap for mental disorders and a relative paucity of empirical evidence about how to fill this gap. This is more so for severe mental disorders, such as psychosis, which impose an additional vulnerability for human rights abuse on its sufferers. A major factor for the lack of evidence is the few numbers of active mental health (MH) researchers on the continent and the distance between the little evidence generated and the policymaking process. Methods: The Partnership for Mental Health Development in Africa (PaMD) aimed to bring together diverse MH stakeholders in SSA, working collaboratively with colleagues from the global north, to create an infrastructure to develop MH research capacity in SSA, advance global MH science by conducting innovative public health relevant MH research in the region and work to link research to policy development. Participating SSA countries were Ghana, Kenya, Liberia, Nigeria and South Africa. The research component of PaMD focused on the development and assessment of a collaborative shared care (CSC) program between traditional and faith healers (T&FHs) and biomedical providers for the treatment of psychotic disorders, as a way of improving the outcome of persons suffering from these conditions. The capacity building component aimed to develop research capacity and appreciation of the value of research in a broad range of stakeholders through bespoke workshops and fellowships targeting specific skillsets as well as mentoring for early career researchers. Results: In the research component of PaMD, a series of formative studies were implemented to inform the development of an intervention package consisting of the essential features of a CSC for psychosis implemented by primary care providers and T&FHs. A cluster rand was next designed to test the effectiveness of this package on the outcome of psychosis. In the capacity building component, 35 early and midcareer researchers participated in the training workshops and several established mentor mentee relationships with senior PaMD members. At the end of the funding period, 60 papers have been published and 21 successful grant applications made. CONCLUSION: The success of PaMD in energising young researchers and implementing a cutting-edge research program attests to the importance of partnership among researchers in the global south working with those from the north in developing MH research and service in LMIC.
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    Mental health and wellbeing of medical students in Nigeria. A systematic review
    (Taylor & Francis, 2019) Esan, O. B.; Esan, A.; Folasire, A.; Oluwajulugbe, P.
    In additional peculiar contemporary social problems due to income inequality, poverty, insecurity and political instability. These have a direct impact on their mental health and wellbeing. The aim of this study was to systematically review articles reporting on the epidemiology of psychiatric disorders among medical students in Nigeria. Studies were identified using MEDLINE, HINARI, African Journal Online (AJOL) and Google Scholar databases using search terms encompassing psychiatric morbidity amongst medical students. No date restrictions were applied to the search. The pooled prevalence estimate was calculated for each disorder. Psychological dis tress was present in 25.2% of the students, perceived stress in 60.5%, depression in 33.5% and anxiety in 28.8%. The current use of at least one psychoactive substance was present in up to 44.2%, while 35.5% of all the respondents had experienced one or more forms of abuse during their training as medical students. The prevalence of psychiatric disorders among medical stu dents in Nigeria is high. Positive coping mechanisms such as religiosity, positive reframing and resilience which were identified in this review should be optimized to reduce the burden.
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    Depression and anxiety disorders amongst a cohort of infertile women attending an in-vitro fertilization clinic in south-western Nigeria.
    (Zambia Medical Association, 2019) Obajimi, G.O.; Esan, O.B.; Ogunkinle, B. N.
    Background: Psychological consequences of infertility have been documented in both developed and less developed countries. Depression and anxiety disorders have been identified as important causative factors. The prevalence of psychiatric morbidity amongst infertile women has been shown to be quite high with values as high as 46.4%. A high premium is placed on childbirth in Nigeria and failure to conceive is associated with disastrous consequences. Failed In-Vitro Fertilization (IVF) cycles have been implicated in psychological distress. Objective: This study aimed to determine the prevalence of anxiety and depression amongst infertile women undergoing IVF and to examine the psychosocial stressors associated with the development of these morbidities. Materials and Methods: A descriptive cross sectional study of fifty-one infertile women attending an In-Vitro Fertilization clinic in Lagos, South Western, Nigeria. Participants were recruited consecutively at their first consultation visit and a self-administered questionnaire consisting of sociodemographic information along with the Hospital Anxiety and Depression Scale (HADS) was completed by the participants. Data obtained from the respondents was analyzed using the Statistical Package for Social Sciences (IBM SPSS, New York) version 21. The Chi-Square statistic was used in testing for associations between categorical variables. Results: The mean age of the respondents was 38.96 ± 5.91 years with a range of 23-49 years. 76.5% (39/51) of the women had infertility greater than 5 years, while 49 % (25/51) of the women were aged 40 years and above with 96% (24/25) of this group experiencing infertility greater than 5 years. Anxiety was recorded in 24 respondents (47.1%) while Eighteen respondents (35.3%) had evidence of depression. Marital disharmony was found to be associated with the development of anxiety (P<0.05) Conclusion: The impact of infertility on the Nigerian couple can be devastating. Lack of support coupled with the overbearing and intrusive nature of family members predisposes to the development of psychosocial distress. We therefore recommend that Physicians pay attention to the psychosocial stressors experienced by infertile women prior to In Vitro Fertilization with the aim of ensuring appropriate referral for psychiatric assessment and treatment.