Scholarly works in Psychiatry

Permanent URI for this collectionhttps://repository.ui.edu.ng/handle/123456789/536

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Subject: search.filters.subject.Bipolar disorder

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    Neurocognitive Impairments (NCI) in bipolar disorder: Comparison with schizophrenia and healthy controls
    (Elsevier B.V, 2020) Esan, O. B.; Oladele, O.; Adediran, K. I.; Abiona, T. O.
    Background: Neurocognitive impairments (NCI) are common in patients with bipolar I disorder. However, reports about the affected domains, outcomes and magnitude have been inconsistent. The aim of this study was to compare the magnitude (severity) and specificity (domains), of (NCI) in euthymic Bipolar I Disorder (BD) patients with a demographically and educationally matched sample of patients with schizophrenia in remission (SC) and healthy controls (HC). Methods: The Screen for Cognitive Impairment in Psychiatry (SCIP) was applied in this cross-sectional study, to all consecutive and consenting euthymic outpatients with bipolar I disorder (BD) (n = 76), remitted patients with schizophrenia (n = 130) and age and gender-matched healthy controls (HC) (n = 100). The cognitive tests done included Verbal List Learning-Immediate (VLT-I), Working Memory Test (WMT), Verbal Fluency Test (VFT), Verbal Learning Test-Delayed (VLT-D) and Processing Speed Test (PST). Within the bipolar group, the association between NCI and functioning was assessed. Results: There was a significant difference in the proportions of participants that had cognitive impairment from the 3 groups (37% (HC) vs. 71.1% (BD) vs. 91.5%(SC) (p=0.001) The BD group in comparison to the HCs did worse on all domains of the SCIP except WMT and PST. The BD group was not significantly different from the SC group in all neuropsychological domains of the SCIP except WMT. BD group significantly functions better than the SC group. The severity of depressive symptomatology and VLT-I were independent predictors of functioning in the BD group. Conclusion: Cognitive impairment affects almost all the neurocognitive domains of the BD group. The difference in NCI between euthymic BD patients and SC in remission are quantitative rather than qualitative.
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    The self-perceived health-care needs of patients with bipolar disorder in Nigeria.
    (Springer Nature, 2018) Esan, O.B.; Medubi, A.
    Few studies have examined the health care needs of patients with bipolar disorder. The aim of this study was to comprehensively assess the clinical and social needs of patients with bipolar disorder in Nigeria and to study the demographic and clinical correlates of such needs. This was a cross-sectional study. Consecutive and consenting out patients with bipolar disorder (n = 100), were assessed with the Camberwell Assessment of Needs Short Appraisal Schedule, the Interpersonal Support Evaluation List-Shortened Version (ISEL-12), the World Health Organization Quality of life-BREF and the Young Mania Rating Scale (YMRS). The most frequently rated areas of total needs as well as unmet needs were in the domain of sexual expression, intimate relationships and the need for company. The mean number of total needs per participant was 10.70 while the median number of unmet needs was 1.50. The total number of unmet needs was significantly higher for unremitted participants compared to remit ted participants. The total number of unmet needs was positively correlated with the severity of manic symptoms (YMRS score) and negatively correlated with the level of social relationships (social domain of WHOQOL), functioning (Global Assessment of Functioning (GAF) score) and social support (Tangible Support subscale of the ISEL). The GAF score and YMRS score significantly predicted unmet needs. The study underscores the importance of assessing the needs of patients with bipolar disorder in Nigeria.