Scholarly works in Community Medicine
Permanent URI for this collectionhttps://repository.ui.edu.ng/handle/123456789/12282
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Item Evaluation of the effectiveness of computed tomography in the diagnosis of orbital tumours in ibadan, southwest Nigeria(West african College of Surgeons, 2013) Akinmoladun, J. A.; Adeyinka, A. O.; Uchendu, O.; Akinmoladun, V. I.Background: The orbit is a bony cavity within the skull that is composed of many structures which may undergo neoplastic transformation. Failure to diagnose the tumour and determine its extent may lead to high morbidity and mortality. The aim of this study was to evaluate the role of computed tomography in the diagnosis of orbital tumours in our centre. Materials and methods: Computed Tomography images acquired from a multi-sliced CT machine, tissue diagnoses obtained from histopathology reports and patients' clinical records were reviewed. The data were analyzed and presented using frequency tables, percentages and charts as appropriate. Results: Sixty six patients made up of 34 (51.6%) males and 32 (48.4%) females were studied. The ages ranged between 1 and 80 years with a mean of 35 years. Majority (50%) of the patients were in their 4th – 6th decades of life. While secondary orbital tumours were seen in 42 (63.6%) patients, primary tumours occurred in 23 (34.8%) cases. Metastatic deposit was seen in 1 (1.6%) patient. Bone was the most commonly affected orbital tissue. The CT diagnoses of benign and malignant tumours were accurate when compared with histopathological diagnoses in 80.6% and 96.7 % of the cases respectively. Conclusion: Computed Tomography is useful in characterizing the nature, precise location of a lesion within the orbit and to demonstrate the extension of the orbital lesion into contiguous structures. This study showed that Computed tomography is also a useful imaging technique in the diagnosis of orbital tumours with high concordance rate when compared with histological diagnoses.Item Evaluation of the Haemodynamic and Metabolic Effects of Local Anaesthetic Agent in Routine Dental Extractions(Springer, 2013) Akinmoladun, V. I.; Okoje, V. N.; Akinosun, O. M.; Adisa, A. O.; Uchendu, O. C.Introduction: The systemic effects of adrenaline adminisitered during dental local anesthesia have been the subject of many studies. The purpose of this study was to investigate the haemodynamic and metabolic effects attributable to adrenaline injected during local anesthesia in dental extraction patients. Methods Apparently medically fit patients were included and randomized into two groups. Participants had breakfast before coming in for tooth extraction. The weight, height, blood pressure and pulse rate were measured and blood sample taken before administration of local anaesthetic injections. Blood pressure, pulse and blood sample were again taken at 15 and 30 min. Results: While the adrenaline group showed a modest increase between pre- and post-drug administration states, the control group showed no difference in median systolic blood pressures. Both groups showed a slight increase in diastolic blood pressure observed between pre- and post drug administration states. Also both groups showed no significant difference in median pulse rate throughout. Although blood glucose values were widely dispersed in the pre-drug administration state in both groups, the control group showed no difference in median values throughout. However, a modest increase was observed in the adrenaline group between pre- and post-drug administration states, which persisted beyond 30 min. Conclusion: The patients treated with local anesthesia with adrenaline showed a response similar to that observed in the control group.