Anti-inflammatory and antimicrobial activities of hippocratea indica root bark and poga oleosa fruits
| dc.contributor.author | Ogbole, O. O. | |
| dc.contributor.author | Ekor, M. N. | |
| dc.contributor.author | Oluremi, B. B. | |
| dc.contributor.author | Ajaiyeoba, E. O. | |
| dc.contributor.author | Gbolade, A. A. | |
| dc.contributor.author | Ayoola, M. A. | |
| dc.contributor.author | Adeyemi, A. A. | |
| dc.date.accessioned | 2026-02-18T11:47:29Z | |
| dc.date.issued | 2007 | |
| dc.description.abstract | The methanolic extracts of Hippocratea indica root bark and Poga oleosa fruits were investigated for anti-inflammatory and antimicrobial activities. Both extracts inhibited carrageenan-induced paw oedema significantly in rats in a dose-dependent manner in 4 h. H. indica inhibited oedema significantly at the minimal dose (125 mg/ml, p< 0.05) from 2 h onward, and gave 100% inhibition in 4 h. at 250 mg/kg. It was shown to be a more potent anti-inflammatory agent than P. oleosa. Also, H. indica extract exhibited greater antimicrobial activity against tested bacteria, with Staphylococcus aureus being the most susceptible bacterium (MIC, 16 mg/ml). Both plants were inactive against Candida albicans. These results confirm the anti-inflammatory and antibacterial activities of the two plants. | |
| dc.identifier.issn | 0189-6016 | |
| dc.identifier.other | ui_art_ogbole_anti-inflammatory_2007 | |
| dc.identifier.other | African Journal of Traditional, Complementary and Alternative Medicines 4(3), pp. 372-376 | |
| dc.identifier.uri | https://repository.ui.edu.ng/handle/123456789/12277 | |
| dc.language.iso | en | |
| dc.subject | Hippocratea indica | |
| dc.subject | Poga oleosa | |
| dc.subject | Anti-inflammatory | |
| dc.subject | Antimicrobial | |
| dc.title | Anti-inflammatory and antimicrobial activities of hippocratea indica root bark and poga oleosa fruits | |
| dc.type | Article |