IgG Enzyme-linked Immunosorbent Assay (ELISA) for immunodiagnosis of Schistosoma haematobium infected subjects living in an endemic Nigerian village
| dc.contributor.author | Oniya, M. O. | |
| dc.contributor.author | Omosun, Y. O. | |
| dc.contributor.author | Anumudu, C. I. | |
| dc.contributor.author | Nwuba, R. I. | |
| dc.contributor.author | Odaibo, A. B. | |
| dc.date.accessioned | 2018-10-08T13:15:20Z | |
| dc.date.available | 2018-10-08T13:15:20Z | |
| dc.date.issued | 2011-04 | |
| dc.description.abstract | Schistosoma haematobium infects school children in areas where the disease is endemic. This study was carried out to determine the reliability of IgG Enzyme-Linked Immunosorbent Assay (ELISA) as an immunodiagnostic tool, using whole antigen derived from Schistosoma eggs. Children of school going age living in Ipogun village, in south western Nigeria; a schistosomiasis endemic community; were used in this study. The sensitivity of the IgG ELISA in detecting positive cases was 68.0% and there was a significant correlation (P < 0.05) between IgG titres and the intensity of infection. However, the specificity was 59.3%, slightly lower than the sensitivity. Results from this study shows that IgG ELISA can be used as a diagnostic tool for determining S. haematobium infection, as it provides an evidence for the intensity of the infection in the infected individuals. | en_US |
| dc.identifier.issn | 1992-2248 | |
| dc.identifier.other | Scientific Research and Essays 6(7), pp. 1650-1655 | |
| dc.identifier.other | ui_art_oniya_igG_2011 | |
| dc.identifier.uri | http://ir.library.ui.edu.ng/handle/123456789/1080 | |
| dc.language.iso | en | en_US |
| dc.publisher | Academic Journals | en_US |
| dc.title | IgG Enzyme-linked Immunosorbent Assay (ELISA) for immunodiagnosis of Schistosoma haematobium infected subjects living in an endemic Nigerian village | en_US |
| dc.type | Article | en_US |