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Author: search.filters.author.Arowojolu, A.O

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    Serum levels of vitamin D in male partners of women with infertility in a tertiary hospital in Nigeria.
    (College of Health Sciences, University of Ibadan, Nigeria., 2023-01) Bamgboye, A. E.; Ogunbode, O.O.; Arowojolu, A.O
    Globally infertility affects 8-12% of couples, with male and female causes contributing equally. Micronutrient's deficiency such as vitamin D has been implicated as a cause of infertility in animal studies, there is therefore the need to evaluate its role in humans. This study determined serum levels of vitamin D in males who were partners of patients presenting with infertility. This was a prospective cross- sectional study involving 170 consenting male partners of women presenting with infertility at the University College Hospital (UCH), Ibadan. A structured questionnaire was administered while blood sample and semen were collected for serum vitamin D assay and seminal fluid analysis (SFA) analysis. The data was entered into the Statistical Package for Social Sciences version 21 and statistical significance was set at less than 5%. Eighty-four (49.4%) participants had at least one abnormal parameter on SFA. The mean vitamin D level was higher in participants with normal SFA (34.4+12.6ng/ml) compared with abnormal SFA (32.8 + 15ng/ml). None of the participants had vitamin D deficiency, however the prevalence of vitamin D insufficiency among participants with abnormal and normal SFA was 62.5 % and 37.5% and this was statistically significant. (p = 0.01). Sperm progressive motility was the only SFA parameter associated with serum Vitamin D levels. (p-value = 0.03). This study showed that vitamin D insufficiency is associated with male infertility, therefore it may be added as an investigation for men with infertility and Vitamin D supplement be given where insufficiency or deficiency are noted.
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    A comparative review of the efficacy of 24-hour versus 48-hour dose regimen of amoxicillin/ clavulanic acid prophylaxis for postoperative infections following elective caesarean section at the University College Hospital, Ibadan, Nigeria.
    (Zambia Medical Association, 2022) Oloko, O.O.; Ogunbode, O.O.; Obajimi, G.O.; Arowojolu, A.O
    Objectives: To compare the efficacy of 24 hour versus 48 hour prophylaxis of amoxicillin/clavulanic acid in the prevention of postoperative infections. Study Design: This study was a randomized controlled clinical trial conducted in a tertiary hospital in Ibadan, Nigeria. Two hundred and fifty - two pregnant women scheduled for elective caesarean section were randomly assigned into two groups. After the initial pre-incision antibiotic a dmi n i s t r a t i o n , g r o u p A r e c e i v e d t h e Amoxicillin/Clavulanic Acid for 24 hours while group B received the same drug for 48hours. Main Outcomes: Participants were examined on the3rd, 10th and 17th post-operative days for evidence of infections. All entry and analysis of data was by computer using the Statistical Package for Social Sciences version 22 (IBM, New York).Statistically significant differences were determined at p value of< 0.05. Results: The incidence of postoperative wound infection, postoperative fever and endometritis in this study was 5.2%, 9.1% and 5.6% respectively. There were no significant differences in the incidence of postoperative wound infection, postoperative fever and endometritis between the two regimens of antibiotics.