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Item Estimating admission lifetime and survival for gynaecological cancers at the University College Hospital, Ibadan using Cox regression model.(2021) Folorunso, S. A.; Oluwasola, T. A. O.; Chukwu, A. U.Objective: To estimate the admission lifetime of gynaecological cancer patients in the University College Hospital (UCH), Ibadan and its implication to management and overall outcome using the Cox regression model. Methods: Descriptive and cox regression model in survival analysis were used to analyze data from 823 patients with gynecological malignancies who were treated at the UCH, Ibadan between January 1 1995 and December 31, 2014. The outcome variable for this study was the admission life-time (in days). The variables collected were limited to the age of patients, types of cancer and patients’ status. The study employed some model criteria such as p-value, log rank test, Gehan-Wilcoxon test, Concordance index, R-square, likelihood ratio test, Wald test and score test to check for the efficiency of the results. Results: Of the 823 cases reviewed, 611(74.2%) were right-censored. Cervical cancer had the highest number of patients admitted with 53.5% and was commonest among patients aged 60 years and above (30.1%) while mortality was highest among patients with ovarian cancer. Ovarian cancer and age above 65 years were the only two factors that significantly affected patient’s survival experiences during their admission at the hospital. Conclusion: Patients younger than 60 years and with other gynaecologic cancers, except ovarian, had better chances of survival over a period of 6 months as at the time of admission into the UCH, Ibadan.Item Comparative efficacy of visual inspection with acetic acid versus cytology for cervical cancer screening in Ogbomoso, Nigeria.(2017) Abiodun, A. B.; Durodola, A. O.; Ajani, M. A.; Amole, I. O.; Abiodun, A. D.; Oluwasola, T. A. O.Background: Screening test for cervical cancer using visual inspection with acetic acid (VIA) has been advocated by World Health Organization as a suitable, low cost and feasible alternative modality for control of cervical cancer in resource-poor settings as compared to cytological and colposcopic screening. The need for reproducibility, accuracy and comparable efficacy will influence the acceptability of VIA as primary screening modalities for cervical cancer. Methods: A cross–sectional comparative study conducted at BUTH. Data were obtained from 318 consenting women aged 30–65 years using a systematic random sampling method and an interviewer–administered structured questionnaire. Pap smear samples were taken followed by visual inspection with acetic acid. Using Statistical Package for Social Sciences (SPSS) version 23.0, Frequencies were obtained and Chi-square test (X2) was used to compare rates and proportions with the level of statistical significance set at less than 0.05. Results: Positive results for premalignant cervical lesion was 1.3% and 4.1% for VIA and Pap smear respectively (X2=4.52; p=0.034). The sensitivity of VIA was 7.7% with positive predictive value of 25% while specificity was 99.0% with a negative predictive value of 96.2%. The prevalence of abnormal cervical lesion in the population studied was 4.1% (95% CI 2.2% – 6.9%). Conclusions: The detection rate for pre-cancerous lesions of the cervix using VIA was significantly lower than that of Pap smear in this study. There may be needed to exercise caution in adopting VIA as primary screening modality for cervical cancer.Item Building capacity to control cervical cancer in Nigeria: a case study(IOP Publishing, Cairo, 2022) Adewole, I. F.; Oluwasola, T. A. O.; Morhason-Bello, I. O.