scholarly works

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Author: search.filters.author.Ajibade, T. O.Has files: Yes

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    Saponins – A ubiquitous phytochemical: A review of its biochemical, physiological and pharmacological effects
    (Studium Press LLC, 2014) Soetan, K. O.; Ajibade, T. O.; Akinrinde, A. S.
    Saponins are ubiquitous phytochemicals widely reported to be present in many species of plants and animals. Some saponin containing plants, mainly legumes, have been used as animal feed, but others are toxic. In this review, the biochemical, physiological and pharmacological effects of saponins in humans and animals have been highlighted. Physiological and biochemical effects examined include the effects on biological membranes, gastrointestinal absorption, blood and liver cholesterol, enzymes and general body metabolism, reproductive, antioxidant and free-radical scavenging effect, smooth muscle activity and effects on ruminant digestion. Pharmacological effects of saponins such as anti-inflammatory, diuretic, hypoglycaemic, antidiabetic, antiulcer and anti-ageing effects are also examined. From the literature reviewed, it can be concluded that saponins, in general, are toxic when administered intravenously but possess a lot of therapeutic potentials especially as cytotoxic agents.
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    Preliminary studies on the haematological parameters of cockerels fed raw and processed guinea corn (Sorghum bicolor)
    (Nigerian Society for Animal Production, 2013) Soetan, K. G.; Akinrinde, A. S.; Ajibade, T. O.
    The effect of feeding raw and ground guinea com [Sorghum bicolor L. Moench) on the haematological parameters of chicken was investigated in this study. Ten (10) 6-week old cockerels were randomly divided into two groups, A and B, and were fed raw and processed (dried and ground) guinea corn, respectively, for two weeks. Packed cell volume (PCV), Haemoglobin (Hb), Red blood cell count (RBC), White blood cell, count (WBC), neutrophils, eosinophils, lymphocyte and monocyte counts were determined before and after the duration of feeding the cockerels with guinea corn. Although significant changes were not observed in most of the haematological parameters, birds fed with processed guinea corn however had a significantly higher red blood cell (RBC) count than birds fed with the raw guinea corn. These findings suggest that feeding of processed guinea corn to cockerels may be more advantageous than feeding of raw guinea corn.