FACULTY OF CLINICAL SCIENCES
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Item Demographic and clinical profile of patients with juvenile onset open angle glaucoma in southwestern Nigeria(Wolters Kluwer - Medknow, 2011-12) Komolafe, O.; Olawoye, O.; Fafowora, O.; Ashaye, A.; Baiyeroju, A. M.Background: This was a non-comparative, retrospective review of patients diagnosed with juvenile open angle glaucoma (JOAG) in the eye clinic of a tertiary hospital in southwestern Nigeria. Objective: To document the demographic characteristics, clinical features and treatment outcome of the patients diagnosed with JOAG. Materials and Methods: Data were extracted from the clinical record of patients diagnosed with JOAG in the eye clinic of the University College Hospital, Ibadan, Nigeria, between January 2001 and December 2005. Such data included the basic demographic data, the clinical characteristic of the patients and the outcome of their treatment. Results: Twenty-nine patients were reviewed, which represents 3.4% of all newly diagnosed glaucoma patients seen in the out-patient section of the eye clinic of the University College Hospital, Ibadan, over the period reviewed. Eight (27.6%) patients were aged 20 years and below. The mean age was 25.1 ± SD 6.0 years. Eighteen (62.1%) had visual acuity of 6/18 or worse in the better eye at the time of presentation. The mean intraocular pressure (IOP) of the patients at presentation was 32.3 ± SD 15.2 mmHg. Eight (27.6%) patients defaulted within 6 months of presentation. The mean IOP for the 21 patients who were followed up on treatment for a mean period of 9.6 months was 17.0 ± SD 6.0 mmHg. Conclusion: Most patients with JOAG in this review presented with advanced form of the disease. Early detection through parent-driven school eye health program and community-based case detection could help in reducing the scourge arising from JOAG among our population.Item Comparative review of burns with inhalation injury in a tertiary hospital in a developing country(2016) Iyun A.O.; Ademola S.A.; Olawoye, O.; Michael A.I.; Oluwatosin O.M.Objective. Inhalation injury is an acute respiratory tract insult caused by direct thermal injury, carbon monoxide poisoning, or toxic chemical inhalants, such as fumes, gases, and mist. The aim of this study is to review the authors’ experiences in a regional burn unit in a developing country. Methods. The university college Hospital, Ibadan, Nigeria prospective burn unit database was retrospectively reviewed from January 2001to December 2013and analyzed using SPSS software, version 16 (SPSS Inc, Chicago, IL). Results. There were 840 patients in all, 63% (527) had cutaneous burns only, while 37%(313) had associated inhalation injury. There was a male preponderance in both groups. Those with cutaneous burns only and those with associated inhalation injury had a male to female ratio of 1.6;1 and 1.5:1, respectively. The mean ages were ears (inhalation injury) and 21 years ± 17 years cutaneous burn only) (P < 0.05). The mean total body surface area (TBSA) of the burn injuries was 55% (inhalation injury) and 25% cutaneous burn only) (P < 0.05). Burn injury occurred most frequently between 19.00 hours and 24.00 hours, and 56% of burn es that occurred during this time were associated with inhalation injury (P < 0.05). Major causes of burns were flames and scalding (86.2%). Mortality was 71% in patients with inhalation and 26% in patients with cutaneous burns only (P < 0.05). Conclusion. The association of inhalation injury with cutaneous burns portends a grave condition. An upgrade of expertise and infrastructure in the management of these patients is necessary in order to improve outcomes.