FACULTY OF CLINICAL SCIENCES
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Item The gateway hypothesis of substance abuse: an examination of its applicability in Nigeria general population(Informa Healthcare USA, Inc., 2010) Makanjuola, V. A.; Oladeji, B. D.; Gureje, O.The study aims to estimate the prevalence and predictors of not following the gateway theory. Respondents were selected from a multistage stratified clustered sampling of households in five of Nigeria’s six geopolitical regions. Interviews were conducted between February 2002 and May 2003 using the CIDI-version.3 with a total sample size (N) of 2,143. Cumulative incidence proportions of not following a gateway pattern were estimated with SUDAAN. Predictors of this were estimated using multivariate logistic regression models. The deviation from the normative sequence of drug use occurs albeit infrequently. The public health implications of this are discussed as well as the limitations of the findings.Item Clinical correlates of schizophrenia: a study at the University College Hospital, Ibadan(2002) Morakinyo, J. J.; Oladeji, B.; Odejide, A. O.Item Neuropsychological evaluation for persons with HIV and AIDS(Oxford University Press, 2017-05) Oladeji, B. D.; Robertson, K. R.Item Global neuroAIDS(Springer, 2015) Oladeji, B. D.; Yosief, S.; Robertson, K. R.Item Mental health(Cambridge University Press, 2013) Gureje, O.; Oladeji, B.Item Mental health and HIV in Africa(Jones and Bartlett Learning, 2012) Oladeji, B. D.; Gureje, O.Item Women, depression, and mental-physical comorbidity: chronic pain as a mediating factor(Cambridge University Press, 2009) Gureje, O.; Oladeji B.Item Mental Health: morbidity and impact(San Diego Elsevier Academic Press, 2008) Gureje, O.; Oladeji, B.Item 30-day all-cause mortality rate amongst older patients admitted to the medical ward of a tertiary hospital in Nigeria.(Medknow / Obafemi Awolowo University, 2021) Adebusoye, L.; Cadmus, E. O.Introduction: Older people face challenges in the overburdened health‑care services in Nigeria, especially when hospitalised. Few available studies on mortality were retrospective, oftentimes with incomplete data which may affect the establishment of the outcome. Objectives: This study determined the 30‑day all‑cause mortality rate (MR) and associated factors amongst older patients in the medical wards of University College Hospital, Ibadan. Materials and Methods: A prospective cohort study of 417 patients (>60 years) from the 1st day of admission to death or discharge at the end of 30th day of admission. Data were collected with a semi‑structured questionnaire. Information obtained included respondents’ sociodemographic characteristics, anthropometric measurements, frailty and functional status. Others were morbidity profile, quality of life, cognition, nutrition, anxiety and depression. Data were analysed using SPSS version 24 at a level of significance P < 0.05. Results: The mean age was 71.6 ± 8.1 years and 216 (51.8%) were females. Eighty‑seven (20.9%) deaths were recorded. The unadjusted 30‑day all‑cause MR was 13.7 deaths (95% confidence interval [CI]: 11.0–16.9/1000 patient‑days). This was significantly higher amongst males than females with a MR ratio (MRR) of 1.93 ([95% CI: 1.23–3.05]; P = 0.01). Factors significantly associated with mortality were being financially self‑supporting (MRR = 2.82; 95% CI: 1.01–6.41), having a cognitive impairment (MRR = 1.92; 95% CI: 1.12–3.20), frailty (MRR = 1.65; 95% CI: 1.01–2.84), ischemic heart disease (MRR = 1.93; 95% CI: 1.18–3.07) and acute exacerbation of bronchial asthma (MRR = 3.92; 95% CI: 1.04–9.42). Conclusion: The 30‑day MR was high amongst older patients, especially the males. Modifiable factors contributing to hospital mortality should be addressed at admission.Item Qualitative exploration of health system response to COVID-19 pandemic applying the WHO health systems framework: Case study of a Nigerian state(Elsevier, 2021) Akinyemi, O.O.; Popoola, O.A.; Fowotade, A.; Adekanmbi O.; Cadmus, E.O.; Adebayo. A. M.Pandemics can result in significantly high rates of morbidity and mortality with higher impact in Lower- and Middle-Income Countries like Nigeria. Health systems have an im- portant role in a multi-sector response to pandemics, as there are already concerns that COVID-19 will significantly divert limited health care resources. This study appraised the readiness and resilience of the Nigerian health system to the COVID-19 pandemic, using Oyo State, southwest Nigeria, as a case study. This study was a cross-sectional qualita- tive study involving key informant and in-depth interviews. Purposive sampling was used in recruiting participants who were members of the Task Force on COVID-19 in the state and Emergency Operations Centre (EOC) members (physicians, nurses, laboratory scientists, "contact tracers", logistic managers) and other partners. The state's health system response to COVID 19 was assessed using the WHO health systems framework. Audio recordings of the interviews done in English were transcribed and thematic analysis of these tran- scripts was carried out using NVIVO software. Results show that the state government re- sponded promptly by putting in place measures to address the COVID-19 pandemic. How- ever, the response was not adequate owing to the fact that the health system has already been weakened by various challenges like poor funding of the health system, shortage of human resources and inadequate infrastructure. These contributed to the health system's sub-optimal response to the pandemic. In order to arm the health system for adequate and appropriate response during major health disasters like pandemics, fundamental pillars of the health system-finance, human resources, information and technology, medical equip- ment and leadership - need to be addressed in order to have a resilient health system.