Pharmacognosy
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Item Ethnobotanical study of plants used in the management of benign prostate hyperplasia in Ilorin, Nigeria(African Journals Online, 2023) Gegele, I. B.; Ajayi, T. O.; Attah, A. F.; Moody, J. O.Background: Benign Prostate Hyperplasia (BPH) is a prevalent illness in older men. It is a condition where the prostate becomes enlarged and blocks the ease of urine passage out of the bladder. Around 50% of the male population develops symptoms of BPH around 51- 60 years of age. Current therapeutic management options come with undesirable side effects like weight gain, dizziness, and impotence, hence, the need to source for safer alternatives initiated by the acquisition, recording, and preservation of traditional knowledge of medicinal plants. Objective: This study aims to preserve indigenous knowledge by documenting medicinal herbs in use as therapy for BPH. Materials & method: Ethnobotanical survey was carried out in the study areas through interviews using a semi structured questionnaire. Respondents included elderly members of the communities, herbalists, and practitioners of traditional medicine. Quantitative ethnobotany index (Use value index) and descriptive statistics were used to analyse data. Results: 50 respondents were interviewed, 64% were Herb sellers, 22% TMPs, Others 14%. 37 plants belonging to 24 plant families were mentioned in the survey. Methods of preparation of recipes mentioned includes: maceration (37%), decoctions (52%), juice (7%), infusions and paste/powder (4%). Method of administration were majorly oral route. The plant family Fabaceae (19%) had the highest representation. This was followed by the families Annonaceae (8%), Euphorbiaceae (6%), Curcubitaceae, Menispermaceae, Combretaceae, Apocynaceae and Rutaceae with 5% each. Other plant families represented 42% of the total number of plants mentioned. Conclusion: The study areas are endowed with abundant flora which serves as a repository for researchers in the quest to develop less toxic drugs with little or no side-effect for the management of BPH.Item Ethnomedicinal survey of medicinal plants used in the management of diabetes in Ibadan north east and south east, Oyo state, Nigeria(Svedberg Open, 2022) Ajayi, T. O.; Attah, A. F.; Tokede, G. A.Diabetes mellitus, a lifestyle disease, affects 8.3% of the world’s adult population. It is one of the most frequent non-communicable diseases in the modern period with enormous burden due to changes in lifestyle, eating habits, the aging population, and urbanization. This work aimed to document the ethnomedicinal plants used in the management of diabetes among Traditional Medical Practitioners (TMPs), herb dealers, and persons with claims of medicinal plant knowledge in two regions of Ibadan. Data was collected from 100 respondents using a semi-structured questionnaire. Data was examined using descriptive statistics and quantitative ethnobotanical indices. Majority of responders (94%) were females with little or no formal schooling (60%). Sixty plant species belonging to 35 families, and 57 genera were found to be used as antidiabetics in the study areas. The most prominent, being Hunteria umbellata, with the highest Use of Mention Index (UMI-0.56). Plants from the Fabaceae family were most mentioned (23%). The most regularly used plant part is the leaves (25%). Oral route was the main means of administration, with decoction being the most preferred method of preparation. The southwestern Nigeria is rich in unknown plants effective in diabetes control, however, more research is needed to extract, chemically clarify, and describe bioactive components that could be used as lead for the development of new antidiabetic medicines with favorable efficacy and safety profiles.
