Ophthalmology
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Item The relationship between ventricular size and visual function in children with hydrocephalus(1998) Odebode, T. O.; Shokunbi, M. T.; Malomo, A. O.; Familusi, J. B.; Agbeja-Baiyeroju, A. M.; Ogunseyinde, A. O.We examined the relationship between ventricular size and visual function in 50 children (36 males and 14 females) with hydrocephalus. The third and lateral ventricular sizes and the visual function scores did not significantly differ between the sexes. Ventricular enlargement was most pronounced at the trigones and least at the level of the foraminae of Monro. The visual function score correlated inversely with the size of the lateral ventricle measured at the levels of the anterior horn and the trigone and expressed as coronal diameter and "Modified" Evans' ratio (r = 0.49; P = 0.001 and r = - 0.38, P = 0.01 for the anterior horn; r = 0.48, P = 0.00 I and r = -0.35, P = 0.001 for the trigone). The size of the third ventricle did not correlate with visual function score. A "modified" anterior Evans ratio of 0.60 and a trigonal Evans ratio of 0.73 were associated with very low visual function score. Furthermore, there was significant inverse correlation between occipitofrontal circumference (OFC) and visual function (r = -0.6379, P = 0.001), but OFC was not valuable for predicting visual function before the onset of head enlargement.Item Syndromatic hepatic ductular Hypoplasia (Alagille syndrome) in a Nigerian: A Case Report(1998) Akinyinka, O. O.; Akang, E. E. U.; Agbeja-Baiyeroju, A. M.; Osifi, B. O. A.||; Thurham, D.We report what, as far as we are aware, is the first documented case of Alagille syndrome which is characterised by chronic cholestasis, characteristic facies, pulmonary stenosis and defects at the vertebral arch, in a Nigerian girl who presented at the age of two days and was followed up interminently for a period or 10.5 years. The biochemical indices suggestive of choiestasis in the patient improved with age while the height and weigh remained suboptimal. The patient had two percutaneous iiver biopsies with the second biopsy being consistent with paucity of interlobular biie duet syndrome. The characteristic facia features suggestive of the Alagille syndrome and clinical and echocardiographic evidence pulmonary stenosis were first observed at the age or 58) months. This syndrome although rare, should be considered in the differential diagnosis of conjugated hyperbilirubinaemia in Nigerian children.Item Granuloma pyogenicum of the palpebral conjunctiva in an African child(1998-12) Agbeja-Baiyeroju, A. M.; Fafowora, O. F.We report a case of granuloma pyogenicum involving the upper palpebral conjunctiva in a male child with the histopathological features found after excision. This has not been previously reported in an African and there was no history of previous trauma or inflammation of the eyelid. The lesion was associated with an indolent corneal ulcer which took 7 months to heal completely even though no recurrence of the lesion occurred after a complete excision.Item Astigmatism in post-operative cataract patients(1994-12) Agbeja-Baiyeroju, A. M.; Oko, H. O.The aim of the study was to find out the various degrees of post-operative refractive astigmatism in our cataract patients, causes of the astigmatism and ways of minimising this problem. The total number of post-operative refractive astigmatism was determined in patients following cataract surgery. 22% of the patients had an astigmatism of greater than 2 diopters although only 1.9% had the more intolerable astigmatism of greater than 4 diopters. Associated causes for the astigmatism included intraoperative vitreous loss, wound dehiscence, pterygium and corneal scars. With the advent of microsurgery and better magnification, suggestions are made as to how to minimise this condition which, if high proves very intolerable for the patient.