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Item Dirofilaria immitis infection in a three year old doberman: A case report(The University of Veterinary Medicine and Pharmacy in Kosice, 2011) Ajadi, R. A.; Omobowale, T. O.; Igado, O. O.; Adejinmi, J. O.; Adedokun, O. A.; Nottidge, H. OA three-year- old male Doberman that was presented at the Veterinary Teaching Hospital of the University of Ibadan, Nigeria with the complaint of anorexia, bloody diarrhea and weight loss was diagnosed with a chronic form of heartworm disease based on the findings at the physical examination which included a complete blood count, liver function tests and thoracic radiography. The physical examination revealed that the dog’s mucous membranes were pale and there was a copious bilateral mucopurulent ocular discharge present. There was subcutaneous oedema on the ventral thoracic region, while auscultation revealed tachypnea and an irregular heart rhythm. The results of the hematology and liver enzyme tests revealed moderate anaemia, which was normochromic and normocytic. There was mild neutrophilia, eosinopaenia and monocytopaenia. Both the alkaline phosphatase (ALP) and aspartate transaminase (AST) were markedly elevated. Also, the serum albumin concentrations and the albumin/globulin ratio were both markedly lowered. The direct blood smear revealed that the dog was negative for both Babesia canis and Erlichia canis, but positive for microfilaria. The microfilaria was 309 ±30p in length and the anterior and posterior widths were 12±2.4p and 9±1.6ji, respectively. The lateral thoracic radiograph showed that the heart was normal in size, while the pulmonary vasculatures were visible and within normal range. The health of the dog improved following treatment with levamisole and gentaprim. This case confirms the efficacy of levamisole in combination with gentaprim in the management of canine heart worm disease.Item Parasitological studies on agama lizard (agama agama) in Ibadan(American-Euracian Network for Scientific Information, 2011) Omonona, A.O.; Adedokun, O. A.; Adekoya-Gafaar, S.A.The parasitological studies of agama lizard (Agama agama) in Ibadan was carried out by selectively picking sixty growing agama lizards of lengths ranging from 22.9cm to 37.5cm (snout-vent length), from five local governments in Ibadan, Oyo state, Nigeria. The lizards were dissected for the collection of the worms which were found in the stomach, intestine and rectum. The worms were identified with a microscope. Parasitological variables were presented on tables and summarized as percentages. Strongyluris brevicaudata and Thelandros annulatus were the prevalent parasites. Across the five local governments, Strongyluris brevicaudata had the highest infection rate in Ibadan South East (87.50%) while Thelandros annulatus was highest in Ibadan North (75.86%). The prevalence of infection of Strongyluris brevicaudata was higher than Thelandros annulatus. The entire male and female specimens examined were found to be parasitized. Females had higher intensity of infection in Ibadan North (51.72%), South east (54.68%) and North west (53.57%) while the male had the highest infection rate in only two local governments, Ibadan North East (48.44%) and Ibadan South West (49.15%).Item The zoonotic implications of pentastomiasis in the royal python [python regius)(Ghana Medical Journal, 2010-09) Ayinmode, A. B.; Adedokun, O. A.; Aina, A.; Taiwo, V.Pentastomes are worm-like endoparasites of the phylum Pentastomida found principally in the respiratory tract of reptiles, birds, and mammals. They cause a zoonotic disease known as pentastomiasis in humans and other mammals. The autopsy of a Nigerian royal python (Python regius) revealed two yellowish- white parasites in the lungs, tissue necrosis and inflammatory lesions. The parasite was confirmed to be Armillifer spp (Pentastomid); this is the first recorded case of pentastomiasis in the royal python (Python regius) in Nigeria. This report may be an alert of the possibility of on-going zoonotic transmission of pentastomiasis from snake to man, especially in the sub-urban/rural areas of Nigeria and other West African countries where people consume snake meatItem A case of eperythrozoonosis in royal python (Python requis) in zoological garden in Ibadan, Nigeria(Sokoto Journal of Veterinary Sciences, 2010-12) Sonibare, A. O.; Kumshe, H. A; Adejinmi, J. O.; Ajuwape, A. T. P.; Adedokun, O. A.; Adedokun, R. A. M.; Ayoade, G.O.; Akinboye, G.B.Eperythrozoonosis in Royal python reported. Clinical observations included dullness, paleness and jaundiced mucous membrane. Parasitological examination revealed rickettsiae, Eperythrozoon. Stressful condition associated with Royal python in captivity resulted in lower immunity and development of evident infection. Routine screening of Royal Python's prey to prevent transfer of ticks by contact is advocated.Item Seasonal limnological variation and nutrient load of the river system in Ibadan Metropolis, Nigeria(EuroJournal publishing inc., 2008) Adedokun, O. A.; Adeyemo, O. K.; Adeleye, E.; Yusuf, R. K.Ibadan is a highly populated city, characterized by environmental problems arising from improper disposal of solid and liquid wastes, poor wastes collection and handling. We therefore investigated the seasonal limnology and nutrient load of the river system in Ibadan metropolis, Nigeria during the dry season (October 2003-March 2004) and rainy season (August-September 2004). The results revealed that colour, Total suspended solid (TSS), total solids (TS) and total nitrogen were generally higher during the dry season. This suggests that the run-offs have only a diluting effect on these parameters. All the other physical parameters (pH, BOD, DO, COD, TDS, Total hardness) and Nutrient load based parameters (phosphate, sulphate, nitrate and nitrite) were generally higher during the rainy season. Also, in most of the sample points, BOD, TDS, TSS, colour and phosphate levels were relatively higher than the WHO standards for surface water during the two seasons. The poor water quality and nutrient loading observed in the study area has severe consequences on the in-dwelling aquatic flora and fauna. Proper treatment of effluent from industrial processes to acceptable levels, discouraging stagnation of domestic waste and sewage, availability of sewage treatment plants is necessary to curtail the health risk associated with the present level of pollution observed during this study.Item A comparative study of three methods for detecting Fasciola infections in Nigerian cattle(VETERINARSKIARHIV, 2008) Adedokun, O. A.; Ayinmode, A. B.; Fagbemi, B. O.Qualitative examination of Fasciola gigantica eggs in faeces and bile were compared with the detection of precipitating antibodies in sera by agar gel precipitation test (AGPT) in 1000 cattle slaughtered at the Bodija municipal abattoir in Ibadan, Nigeria. Faecal and bile examination methods detected (196) 33.5% and (389) 38.9% of the animals as positive for fasciolosis, while (474) 47.4% were positive by AGPT. Both direct bile examination and faecal egg detection methods have high specificity and positive predictive value (100%) when compared with AGPT. However, lower values for sensitivity and negative predictive value were observed for both faecal egg examination (66.5% and 67.9% respectively) and bile examination (81.0% and 78.9% respectively). Fecal and bile examination failed to detect 33.5% and 19.0% of the cases detected by AGPT. The results of this study revealed that the AGPT could become a better test for the herd diagnosis of bovine fasciolosis for veterinarians and other investigators in Nigeria.Item Seasonal prevalence of fasciola gigantica infection among the sexes in Nigerian Cattle(Medwell Journals, 2008) Adedokun, O. A.; Ayinmode, A. B.; Fagbemi, B. O.This study examined the seasonal prevalence of fasciolosis between tire sexes in Nigerian cattle. The possible role and effect of sex on prevalence of the disease is also discussed. One thousand cattle were examined for infection using the fecal and bile examination for Fasciola eggs and Agar gel precipitation test. Total 750 75%), 448 (44.8%) and 450 (45%) positive were detected by each of tire three methods respectively. The first peak of infection was detected in February' and the second from September to October. Prevalence was higher (52.3%) during the rainy seasons. The annual prevalence was higher in females (63.7%) than in males (36.3%). Prevalence was also higher in females from December to September and peaked (8.1%) in February. Peak prevalence for males occurred in September and October (6.6%), overall prevalence was found to be higher in the females and statistically significant during the dry season.Item Anthelmintic efficacy of the aqueous crude extract of Euphorbia hirta Linn in Nigerian dogs(2005) Adedapo, A. A.; Shabi, O. O.; Adedokun, O. A.The anthelmintic efficacy of the aqueous crude extract of Euphorbia Itirta Linn was studied in 20 Nigerian dogs that were naturally infected with nematodes. They were randomly divided into 4 groups. A, B. C and D. Groups A and B each comprised 4 dogs while groups C and D comprised 6 dogs each. Group A animals were untreated, while those in group B were treated with proprietary anthelmintic (Mebendazole). Groups C and D animals were treated with aqueous crude extracts of E. hirta using intramuscular and oral routes, respectively. Two weeks after treatment, blood and faecal samples were collected to evaluate haematological values and faecal egg counts, respectively. The procedure was repeated two weeks later. Results of this study show that the aqueous crude extracts of E. hirta after its administration into local dogs produced a significant increase (P< 0.05) in PCV, RBC. l ib cone.. TWBC and lymphocyte counts. The faecal egg counts also showed a remarkable and significant reduction in the levels of the identified helminths. The reduction in faecal egg counts was more pronounced with the extract administered through the oral route when compared with the intramuscular route. The effects of the plant extracts were broad spectrum in action. The phenol compound present in the plant extract could have caused reduction in worm load through this same mechanism that culminates in exhaustion and death ofworms. Since the aqueous crude extract of £. hirta significantly reduced the faecal egg count of the helminths, it could serve as an anthelmintic agentItem Infestation of royal python (python regius) with ticks amblyomma hebraeum in Ibadan Zoo, Nigeria(Tropical Veterinarian, 2003) Ajuwape, A. T. P.; Sonibare, A. O.; Adedokun, R. A.; Adedokun, O. A.; Adejinmi, J.O.; Akinboye, D.G.Tick infestation in royal python is reported. Clinical signs included dullness and inactivity evident in reaction to its prey. Parasitological examination revealed Amblyomma hebraeum. Epidemiological investigation showed WAD goat with external parasite within the reptile area.Item Concurent fatal helm1nthosis and balantidos1s in red monkey (Erythrocebuspatas) in Ibadan, Nigeria(Nigerian Veterinary Journal, 2002) Adedokun, O. A.; Adedokun, R. A. M.; Emikpe, B. O.; Ohore, O. G.; Oluwayelu, D.O; Ajayi, O.L.Fresh fecal specimen from a moribund red monkey (Erythrocebuspatas) from the zoological garden, University of Ibadan with a history of dysentery was examined. Ova of Triclmris spp., Enterobius spp, Ancylostoma spp. and Strongyloides spp., as well as Balantidium spp oocysts were found. Post mortem, findings revealed the large intestine heavily infected with worms especially Trichuris spp., Ancylostoma spp. and Trichostronglus spp. which were enmeshed in a thick layer of mucous and blood on the mucosa. The public health importance is discussed.