scholarly works

Permanent URI for this collectionhttps://repository.ui.edu.ng/handle/123456789/581

Browse

Subject: search.filters.subject.Resection

Search Results

Now showing 1 - 2 of 2
  • Thumbnail Image
    Item
    Small bowel responses to enteral honey and glutamine administration following massive small bowel resection in rabbit
    (2008) Evarefe, O.D.; Emikpe, B.O.; Arowolo, R. O. A.
    The trophic effects of honey and glutamine in the healing and adaptation of the small bowel following intestinal resection were studied in some Nigerian non-descript breeds of rabbits. Nine rabbits of mixed sexes with mean body weight of 1.45 ±0.55kg were used. They were randomised into three treatment groups following 50% small bowel resection. Group A rabbits were placed on oral honey treatment. Group B on oral glutamine and group C on normal saline (control). All groups exhibited signs of small bowel adaptation (glutamine(B) honey (A) control (C) at the end of the experiment (4 weeks) with oral glutamine showing the best overall effects on intestinal mucosal growth and adaptation evidenced by significant increase (P<0.05) in residual bow'el length (37.3%), villi width (20.0%), crypt depth (113.3%) and a non significant increase in villus height (33.3%) and cellular mass (10.2%). Honey showed a better effect than control with a significant increase (P<0.05) in villi width (18.2%), crypts depth (66.7%) and cellular mass (33.9%) and a non significant increase in gross residual bow'el length (24.6%), and villus height (30.5%). Our result shows that honey and glutamine have trophic effects on bowel mucosa healing and hyperplasia and have potential therapeutic effects on massive bowel resection in humans
  • Thumbnail Image
    Item
    Morbidity in Nigerian local cats after ileocolic valve or ileocolic valve and ileal resection
    (2011) Eyarefe, O. D.; Akinrinmade, J. F; Wojuoia, O. A.
    The morbidity of excision of the ileocolic valve (Group A), and the ileocolic valve with thirty percent (30%) distal ileal segments (Group B) were evaluated and compared in six adult local cats anaesthesized with xylazine (0.4 mg/kg) and ketamine hydrochloride (22 mg/kg). A non-significant fall (P>0.05) in the haemogram (PCV, Hb, RBC, and WBC), total serum proteins (albumin and globulin) and body weights were recorded among cats in groups A and B, following six weeks of post-operative monitoring. Samples of feces from both groups were non-bloody, non-mucoid and have normal to soft consistency with evidence of improvement over time. The improvement in fecal consistency, body weight and haematological picture over the period of post-operative management was adjudged to be consistent with adaptive changes in the residual intestinal segments. The observed clinical features are discussed in relation with those of massive intestinal resection in cats, dogs and humans. It was concluded that ileocolic valve resection produced little or no detrimental effects on bowel functions of local cats, and local cats could tolerate ileocolic valve with thirty percent (30%) distal ileal resection provided the proximal intestinal segments are intact