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    The Efficacy and Safety of Epicutaneous Immunotherapy for Milk Allergy: A Systematic Review
    (Scala Institute, 2023) Alvarez-Florian, L. M.; Paula-Garcia W. L.; Gutierrez-Brito, G.; Vaisberg, V. V.; Vakharia H.; Moralez, G. M.; Armeno M.; García-Nieto, G.; Sangrador M.; Ndikom, C.M; Ayapati V.A.; Contreras, V.; Montalvan A.; El khatem Y.M.; Hassan, A.; Mohamedahmed A. O. Y.; Horowitz R.
    Introduction: Cow’s milk allergy (CMA) is rising among children and adults, affecting 2-3% of children in affluent countries. Currently, the only standard of care is dairy restriction. However, epicutaneous immunotherapy (EPIT) is being studied as a potential treatment involving transdermal administration of an allergen to induce tolerance. EPIT has been proven safe for managing other food allergies in children and adolescents, but its efficacy for CMA is yet to be determined. Methods: A systematic search of four databases (PubMed, ScienceDirect, SCOPUS, and clinicaltrials.gov) was conducted in September 2022 by three independent reviewers. Additional studies were found by manual reference browsing. All published articles and randomized controlled trials (RCTs) that assessed the effect of EPIT on CMA in children and adolescents aged ≤18 years were included. The search terms used were “epicutaneous immunotherapy” or “immunotherapy” or “EPIT”; “milk allergy” or “cow’s milk allergy” or “CMA” or “CMPA”; “children” or “young” or “kids.” Results: Six studies were included after a systematic search of 123 studies, with three RCTs evaluating the safety and efficacy of EPIT in children with CMA and three meta-analyses and reviews on EPIT for CMA. The findings were inconclusive but suggested the possibility of treating cow’s milk allergy. Discussion: EPIT shows promise in treating food allergies, including CMA. Evidence is lacking to determine its efficacy for CMA. More clinical trials with different dosages and longer follow-ups are needed. Results should be interpreted with caution due to limited studies.
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    Factors Influencing Birth Preparedness and Complication Readiness among Post-Natal Women in Selected Primary Health Centers in Ibadan, Nigeria
    (European Open Access Publishing, 2023) Adeteye, D. E.; Ndikom, C. M.; Akinwaare, M. O.; Dosunmu, T. O.
    Background: Birth preparedness and complication readiness is a strategic intervention to achieve a reduction in the rate of maternal mortality. However, despite the importance and ease of use of this intervention, it has been observed that several factors have hindered the practice. Hence, the need to consider the knowledge, attitude, practice, and factors that influences Birth preparedness and Complication readiness among post- natal women. Method: This descriptive cross-sectional study used a multi-stage sampling technique to select 116 post-natal women in selected primary health centers in Ibadan North Local Government Area, Oyo state. An adapted structured questionnaire was used to assess the knowledge, attitude, practice and factors influencing the practice of birth preparedness and complication readiness. Statistical analysis was done using Statistical Package for the social science (SPSS) version 21.0 software. Descriptive data were presented as frequency and percentages while the chi-square test was used to test the hypotheses at P value < 0.05. Result: The majority of respondents were highly knowledgeable (86.2%). The respondents had a positive attitude towards birth preparedness and complication readiness (75%). The practice level was high among the respondents (71.6%). However, the factors that influenced practice were lack of adequate knowledge (X2-4.578, P=0.032), pre-mature delivery (X2-19.929, P=0.000) and environmental insecurities (X2-6.556, P=0.010). Conclusion: There is a relationship between factors (lack of adequate knowledge, premature delivery and environmental insecurities) and the practice of birth preparedness and complication readiness. Hence, measures should be employed to address the identified factors to improve the practice of birth preparedness and complication readiness.
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    Knowledge of Cervical Cancer and Uptake of Human Papillomavirus Vaccine among Mothers of Adolescents in Ibadan, Nigeria.
    (Faculty of Nursing Sciences, College of Health Sciences, Ladoke Akintola University of Technology (LAUTECH), 2023) Ndikom C. M.; Oyegoke A. A. A.; Chukwuka, L.; Ike, E. U.
    Cervical cancer (CC) is the most common gynecological malignancy in Nigeria, and the Human papillomavirus (HPV) is known to be associated with the disease. Vaccination is an effective preventive strategy, but its uptake remains low in Nigeria. Therefore, this study aimed to assess the knowledge and uptake of HPV vaccination among mothers of adolescents in two selected markets in Ibadan, Nigeria. A descriptive cross- sectional design was employed, and 398 mothers were purposively selected out of the 600 accessible participants. Data was collected using a structured interviewer-administered questionnaire and analyzed using IBM Statistical Package for the Social Sciences version 25. Descriptive statistics, frequency tables, and charts were used for data presentation, while the chi- square test was used for hypothesis testing at a significance level of 0.05. The findings revealed that 46.7% of the respondents were aged 39-48 years. Less than half (47.2%) had a high knowledge level of Cervical cancer and HPV, and only 23.4% had received HPV vaccination, with none of their daughters being vaccinated against HPV. The major perceived factors influencing mothers' uptake of HPV vaccine were a lack of adequate information about the vaccine (87.2%) and not knowing where to get the vaccine (79.4%). There was no significant association between mothers' knowledge and uptake of the HPV vaccine (p=0.487), as well as the cost of the vaccine and its uptake (p=0.998). However, a significant association was found between mothers' educational level and their knowledge of cervical cancer (p=0.000). These findings highlight the need for improved information dissemination on cervical cancer and HPV vaccination. It is recommended that the government initiates national immunization policies to make the vaccine more accessible and affordable, thereby combating the disease effectively.
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    Knowledge and Cervical Cervical Cancer Screening Self-efficacy in Jema’a Local Government Area of Kaduna State, Nigeria.
    (West African College of Nursing, 2023) Adams K.; Ndikom C. M.; Ogunmodede, E. O.; Akomolede E. O.; Peter Z. B.
    Background: Cervical Cancer (CC) is the second most common cancer among women in Nigeria. The women present at the late stage of the disease with no history of screening. Poor knowledge of CC has been reported which could have implications on screening uptake. The study assessed knowledge and cervical cancer screening self-efficacy among women in Jema'a LGA of Kaduna State. Methodology: A descriptive cross-sectional design was utilized and 382 women were selected using systematic random sampling. Data were collected using structured questionnaire. Data were analyzed using descriptive and inferential statistics- Chi-square test at 0.05 level of significance. Results: 167(43.7%) of the respondents had good knowledge on CC. Majority, 315 (82.5%) had high self-efficacy scores. Uptake was low as 227(59.4%) of the respondents had never been screened. There was a significant association between educational level and knowledge of CC screening (X-58.01; p=0.000), religion and self-efficacy (X= 7.873; p=0.020), education level and self-efficacy on CC screening (X-6.980; p=0.008). Conclusion: The women's knowledge and uptake of cervical cancer screening was poor; however, the respondents' self- efficacy was high. There is need for educational interventions to increase knowledge of cervical cancer screening and to make screening services available and accessible to enhance uptake.
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    Knowledge of Human Papilloma Virus Self-sampling and Cervical Cancers Screening Uptake among Gynaecology Clinic Attendees in a Tertiary Hospital in Nigeria
    (Biomedical Communications Group, 2023) Oyedero, L. C.; Ndikom. C. M.; Ojo, I. O.
    Cervical cancer remains a significant contributor to global cancer-specific morbidity and mortality, despite being one of the most preventable and treatable cancers. Uptake and knowledge of cancer screening has remained low in developing countries. Therefore, this study investigated the level of knowledge Human Papilloma Virus (HPV) Self-sampling and Cervical cancers screening uptake among gynaecology clinic attendees in Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife, Nigeria. A cross-sectional design was employed in the study. A total of 256 respondents were selected using simple random sampling technique from two tertiary institutions in Osun State, Nigeria. A semi-structured questionnaire was used to collect data on the knowledge of HPV Self-sampling and cervical screening uptake from the respondents. Data were analysed and presented in percentages and association between variables were tested with logistic regression, chi-square and fisher’s exact test at 0.05 level of significance. The mean age of the respondents was 35.8±9.7 years, age of sex initiation for almost half (48.2%) of the respondents was between 21 and 25 years. Also, 66% of the respondents had not been screened of cervical cancer and 62.9% do not have enough education on self-sampling. However, 75.4.0% had poor knowledge on HPV self-sampling while 21.5% believed only sexually active women can only engage in self-sampling. There was a significant association between socio demographic, utilisation and knowledge of self-sampling for HPV. The study revealed poor knowledge on Human Papilloma Virus self-sampling and low screening uptake. Therefore, there is a need to strengthen the self-sampling knowledge among women for future screening.
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    Psychiatric morbidity among pregnant and non pregnant women in Ibadan, Nigeria
    (Taylor & Francis Group, 2023) Bello, O. O.; Bella-Awusah, T. T.; Adebayo, A. M.; John-Akinola, Y. O.; Ndikom, C. M.; Ilori, T.; Cadmus E. O.; Omokhodion F.
    A comparative cross-sectional study was conducted among 991 pregnant and 674 non-pregnant women of reproductive age attending healthcare facilities in Ibadan, Nigeria using the General Health Questionnaire-12 (GHQ), and WHO self-reporting questionnaire (SRQ). Logistic regression analysis was conducted to identify predictors of psychiatric morbidity at p <0.05. A significantly higher proportion of pregnant women experienced psychological distress on the GHQ (51.8%) and psychiatric morbidity on SRQ (33.3%) compared with 28.6% and 18.2% of non-pregnant women, respectively. Predictors of psychiatric morbidity among pregnant women were the type of facility, poor satisfaction and communication with partners, the experience of violence in the home, previous abortions, and previous history of depression. Psychiatric morbidity among non-pregnant women was predicted by younger age, previous history of depression, poor satisfaction and communication with partners. There is a need for early identification of psychiatric morbidity among women of reproductive age, to ensure early interventions and prevent long-term disability.
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    Knowledge and Experience of Postnatal Women on Respectful Maternity Care During Childbirth in Selected Health Facilities in Nigeria
    (Faculty of Nursing Sciences, College of Health Sciences, Ladoke Akintola University of Technology (LAUTECH), 2022) Adeyemi, D. T.; Kolawole, I. O.; Ndikom, C. M.
    Respectful Maternity Care (RMC) is a lifesaving strategy that encompasses respect for women's basic human rights that includes respect for women's autonomy, dignity, feelings, choices, and preferences. However, the lack of RMC limits maternal health service utilization. It is against this background that this study examines knowledge, experience and satisfaction of women on RMC in selected health facilities in Ibadan. This descriptive cross-sectional study employs a simple random sampling technique to select 151 participants. A self-administered questionnaire with a reliability coefficient of 0.78 was used for data collection. Data collected were analyzed using descriptive statistics and chi-square for hypotheses testing at p<0.05. The findings show that respondents' mean age is 28.60 (+5.914) years. Less than half 69 (45.7%) of them have tertiary education and most of the respondents 89 (58.9%) have one or 2 children. A greater proportion of them, 112 (74.2%) have a positive experience of RMC. Majority, 102 (67.5%) of the respondents are highly satisfied with the RMC received. The respondents' experience of care is found to have a strong influence on their subsequent patronage of the health facilities at (2 8.9351, p= 0.011). Their level of knowledge about RMC is not associated with the experiences of the care they received (x2=6.383, p=0.567). Given the above, efforts should be made to improve the provision of Respectful Maternity Care in order to enhance the use of skilled care at childbirth. This will enhance the achievement of safe motherhood thus preventing maternal mortality and morbidity.
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    Perceived Need for Spousal Support in Maternity Care and Psychosocial Challenges among Couples in Abuja, Nigeria
    (Department of Psychology at the University of Ibadan, Nigeria, 2022) Edu I. B.; Ndikom, C. M.; Ishola, A.G.
    Globally, implementation of continuous spousal support in maternity care remains a challenge despite being known as one of the best practices during childbirth. This study examined the perceived need for spousal support and psychosocial challenges of maternity care in Abuja, Nigeria. This mixed method survey was carried out among 196 couples who had had at least one child from the selected communities. A structured questionnaire was used to elicit information and was analysed using descriptive statistics. Qualitative data was thematically analysed. The mean age of husbands was 41.12±8.87 years; wives was 35.68±7.94 years. Couples had positive perception of spousal support with husbands (90.9%) and wives (95.7%). The reported presence of spouse at delivery of baby was similar, 34.8% by husbands and 36.9% by wives. Major psychosocial factors identified were work schedule (93.6%) for husbands and marital challenges (95.6%) for wives. Poor communication; couples’ perception of maternity care; distance to facility were their major challenges. The qualitative studies showed some discordant responses in their willingness. The couples had positive perception of spousal support but there is need for increased sensitization of couples as willingness to partake in spousal support is just fair. The hospital environment should be more conducive for spouses.
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    Knowledge of Covid-19 and Psychosocial Experiences During the Covid-19 Lockdown among Secondary School Students in Eleyele, Ibadan, Oyo State, Nigeria
    (The International Journal of Caring Sciences, 2022) Oluwatosin, O.A.; Ekelaka C, T.; Ndikom, C. M.
    Background: COVID-19 Is A Highly Contagious Disease That Can Easily Spread from Person to Person and Is a Global Health Threat. The Ongoing COVID-19 Is Inducing Fear and Knowledge of the Disease Will Help to Dissipate Fear. The Lockdown That Was Introduced at the Earlier Onset in Many Countries Including Nigeria Was Sudden and This Had Implication for Physical and Psychological State of Individuals Especially Young People, Who Are Easily Bored. Assessment Of Young People’s Knowledge and Psychosocial Experience During the Lockdown Was the Objective of This Study. This Was Done to Provide Baseline Information About Their Experience During This Unprecedented Event. Methods: A Descriptive Cross-Sectional Survey Was Conducted Among 352 Respondents from Five Schools During the First Reopening of Schools for Those in JSS3 And SSS3 Who Were Due for External Examinations. Simple Random Sampling Was Used for Selection of Schools, While Systematic Sampling Was Used to Select Respondents. Data Were Generated From 28th September to 2nd Of October, 2020. Data Were Analyzed Using Descriptive and Inferential Statistics of Chi-Square Test At 0.05% Level of Significance Results: More Than Half (57.1%) Were Females, 55.7% Were Between 15-19 Years with Mean Age Of 14.7± 1.910, 54.3.0% Were in Third Year of Senior Secondary, 56.8% Were from Oyo State, 84.7% Are from Yoruba Ethnic Group and More Than Half Live with Both Parents. More Than Half (58.8%) Had Good Knowledge Of COVID-19, 56.0% Had Positive Psychological Experiences And 57.7% Had Positive Social Experience. Psychological (P=0.101) And Social Experiences (P=0.192) Were Not Significantly Associated with Level of Knowledge Of COVID-19. Conclusion: More Than Half of the Students Had Good Knowledge Of COVID-19, Positive Psychological and Positive Social Experiences. Regular Health Education About COVID-19 And Its Prevention Is Needed to Sustain the Positive Behavior Among the Students and Curb the Spread Of COVID-19.
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    Psychoeducation for psychological issues and birth preparedness in low- and middle-income countries: a systematic review
    (Elsevier Inc, 2022) Tola Y. O.; Akingbade O.; Akinwaare M. O.; Adesuyi E. O.; Arowosegbe T. M.; Ndikom C. M.; Adejumo P. O.; Alexis O.
    BACKGROUND: Psychological issues usually accompany the pregnancy of first-time mothers, and psychoeducational interventions might be effective in addressing these concerns and preparing first-time mothers for childbirth and the postnatal period. OBJECTIVE: This study aimed to identify, analyze, and synthesize the components and determine the effectiveness of psychoeducational interventions that are used for managing psychological issues and enhancing birth preparedness among primigravid women or couples in low and middle-income countries. STUDY DESIGN: A systematic search of 12 databases (APA PsycINFO, EmCare, Embase, MEDLINE(R), Ovid Nursing, British Nursing Index, Health & Medical Collection, ProQuest, CINAHL, Cochrane, Hinari, and PubMed) was conducted to identify relevant studies published between 1946 and October 2021. The quality of the included studies was appraised by the Joanna and Briggs Institute critical appraisal tool, and a narrative synthesis was performed to analyze data extracted from included articles. The systematic review protocol is registered with the International Prospective Register of Systematic Reviews (registration number: CRD42021237896). RESULTS: The initial search yielded 8658 articles. Of note, 16 articles, including 7 randomized controlled trials and 9 nonrandomized trials, met the inclusion criteria and were selected and reviewed for quality. In addition, 31 outcomes were measured in the studies, including psycho logical outcomes, birth preparedness outcomes, and other outcomes. The design of the interventions included antenatal education that was delivered through lectures, role plays, trainings, and antenatal counseling. All the psychoeducational interventions had a significant effect (P<0.05) Cohen’s d or Hedges’ g=0.2−1.9) on certain psychological outcomes, including childbirth attitude, fear of childbirth, depression, fear, and anxiety, and birth preparedness outcomes. CONCLUSION: Although first-time mothers experience a range of psychological issues during pregnancy, psychoeducational interventions were beneficial in addressing their psychological concerns. It would seem that these interventions are less expensive and could be easily implemented in low- and middle-income countries. However, rigorous research, such as randomized controlled trials, is hereby warranted to standardize the interventions and outcome assessment tools.