FACULTY OF VETERINARY MEDICINE
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Item Haemogram and hormonal profile of WAD buck treated with leaf ethanol extract of spondias mombin(Faculty of Veterinary Medicine, Usmanu Danfodiyo University, Sokoto-Nigeria, 2017) Oloye, A. A.; Ola-Davies, O. E.; Oyeyemi, M. O.Twelve post pubertal West African Dwarf (WAD) bucks of average age of 1.8 ± 0.19 years and average weight of 8.76 ± 0.72 kg were experimentally treated orally with 800mg/kgBW of ethanol extract of Spondias mombin. Experiment was carried out in the month of August at Abeokuta, South West Nigeria with temperature range of 24oC and 33oC on Latitude 07o 10’N and Longitude 03o 2’E. The goats had well-formed pendulous scrotum with well descended free bilateral testicles. The goats were kept in a standard goat pen and fed with fresh green centrosema leaves in the morning and commercially prepared ration in the evening. Water was served ad libitum. Pre-treatment haematological and hormonal profiling after aseptical collection of blood from the bucks was followed with 14 days of oral treatment with ethanol extract of Spondias mombin at the dosage rate of 800mg/kg BW. Post-treatment haematological and hormonal studies followed after. The hormones assayed were follicle stimulating hormone (FSH), luteinising hormone (LH), testosterone, progesterone, estrogen and prolactin. The haemogram revealed significantly (p < 0.05) higher PCV (24.33±0.6 %) in pre-treatment compared to 19.92± 1.1 % recorded for post-treatment. However, both were lower in values than normal range. WBC and RBC did not change significantly but while RBC values for pre-treatment and post-treatment fell within normal range, only the WBC value of post-treatment did. Assay of FSH, progesterone, estrogen and prolactin revealed no significant (p . 0.05) difference between pre-treatment and post-treatment; however, noticeable higher pre-treatment LH concentration and elevated post-treatment testosterone concentration were observed. The work showed that Spondias mombin at 800mg/kgBW has profertility tendencies in the buck and can be considered as an aphrodisiac in goat breeding in developing countries probably at a higher dosage.Item Vital reproductive indices in non gravid female rabbits treated with crude ethanol extract of spondias mombin(University of Veterinary Medicine and Pharmacy In Kosice - The Slovak Republic, 2013) Oloye, A. A.; Oyeyemi, M. O.; Ola-Davies, O. E.; Ajayi, O. I.; Ajayi, A. R.Ten female Chinchilla breed of rabbits with a mean weight of 1.65 ±0.06 kg, were randomly divided equally into a treatment and a control group. The treatment group received orally 800 mg.kg1 of an ethanol extract of Spondias mombin for fourteen days. The control group received only distilled water utilizing the same method of administration. The females were kept separately away from males. Assays of the reproductive hormones before and after treatment with the extract in the treatment group were done. Both groups were sacrificed after fourteen days of oral administration and their reproductive tracts carefully examined. The studies revealed the normal morphology of ovaries, oviduct, uterine horns, and uterine body in both groups. The histological sections of different reproductive segments were normal. Left and right ovaries appeared to show marked oogenesis in the treated group going by the larger number of follicles observed compared to the control. The body weight adjusted mean paired ovarian diameter of the control group (0.51 +0.02cm) was significantly (P<0.05) different from the treated animals (0.41 ±0.39 cm) but this did not translate into a significant difference in the paired ovarian weights. The body weight adjusted lengths, widths and weights of other parts of the reproductive tracts did not differ significantly comparing the treated and control groups, except for the length of the right uterine horn and the weight of the right oviduct. The studies showed that all of the hormones did not change significantly, comparing the pre and post treatment in the treated group. It was concluded that 800 mg.kg-' of ethanol extract of Spondias mombin appeared to favour folliculogenesis in non-gravid rabbits and resulted in no observed pathological effects on the entire reproductive tract of the rabbit.