scholarly works

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Author: search.filters.author.Cadmus, S.I.B.Has files: Yes

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    Seroprevalence and risk factors of brucellosis in goats in selected states in Nigeria and the public health implications
    (2014) Ogugua,A.J; Akinseye,V.O; Ayoola,M.C; Oyesola,O.O; Shima,F.K; Tijjani,A.O; Aderemi,N. A.M; Adesokan,H.K; Lorraine,P; Andrew,T; Stack,J.A; Moriyon,I; Cadmus, S.I.B.
    Available reports on brucellosis in Nigeria are largely confined to cattle while it is believed that other ruminants like sheep and goats are equally exposed to the disease. To have an insight into the role of goats in the epidemiology of brucellosis in Nigeria, we conducted a cross-sectional study between June 2011 and May 2013 to determine the seroprevalence of brucellosis in goats in some selected states in Nigeria. Serum samples were collected from goats at different locations and tested for antibodies to Brucella spp using the Rose Bengal Test (RBT), samples positive by RBT were further subjected to Competitive Enzyme Linked Immunosorbent Assay (cELISA). Data collected to determine risk factors were also analysed using chi-square and logistics regression statistics. Out of a total of 2827 samples tested from the different states (Benue = 331; Borno =195; Oyo = 2155; Sokoto = 146), we recorded an overall seroprevalence of 2.83% (Benue = 17.30%; Borno = 2.05%; Oyo = 0.60% and Sokoto = 0.00%) by RBT. The cELISA further supported 9.45% (7/74) of the total RBT positive samples. Logistic regression analysis showed that the location (p = 0.004) and source (p < 0.0001); are probable risk factors to be considered in the epidemiology of brucellosis with sex (p = 0.179); age (p = 0.791) and breed (p = 0.369) not playing any major role. Our findings reveal a relatively low seroprevalence of brucellosis among goats screened except for Benue State. Since most of the goats sampled in the present study were from the abattoirs, further farm level investigations are required to determine the role of goats in the epidemiology of brucellosis in Nigeria since they share common environment with sheep and cattle that are natural hosts of Brucella species which are of major public health threat.
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    zoonotic risks and transmission of mycobacteria species from cows' milk and slaughtered cattle to man in ibadan:role of butchers
    (2008) Cadmus, S.I.B.; Adesokan,H.K.; Adepoju,A.F.; Otesile,E.B.
    To ascertain the zoonotic risks association with the handling,processing and consumption of milk and meat products in respect to bovine tuberculosis in ibadan. This study was conducted by simultaneous screening of 105 unpasteurised cows milk. samples and 587 slaughtered cattle some of which showed gross lesions suggestive of tuberculosis. samples from the milk and suspected tuberculosis lesions were cultured in lowenstein-jensen media while nitrate and niacin tests were carried out to classify the isolated mycobacteria species. prevalence rates of 5.7% and 4.3% were confirmed from the milk and cattle samples: screened respectively. based on the biochemical tests, three isolates of mycrobacterium tuberculosis, one of M. Bovis and one of M. africanum were identified from the milk samples: while six M. tuberculosis, fourteen M. bovis,two M. africanum and three unclassified mycrobacteria species were obtained from the tuberculous cattle. the unhygenic handling and processing of these animal products by butchers may lead to the zoonotic transmission of M. tuberculosis complex to the public and a source of occupational exposures to the butchers.
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    Meat inspection and cultural isolation of mycobacteriaas predictors of bovine tuberculosis in Ibadan
    (2007) Cadmus, S.I.B.; Alonge, D.O.; Adesokan, H. K.
    In order to ascertain the effectiveness of meat inspection as against the conventional culture method in the confirmation of tuberculosis in cattle slaughtered at Bodija abattoir. Ibadan; a study to assess these two methods in their ability to diagnose bovine tuberculosis was carried out. In all. 290 cattle were inspected at the abattoir out of which 182 had military nodules and granulomatous tubercles in the different organs and their associated lymph nodes which are suggestive of tuberculosis. One hundred and fifty-nine (54.8%) animals were confirmed to have tuberculosis based on the mycobacterial culture. The sensitivity and specificity results of the postmortem examination vis-a vis the culture were 100% and 82.4% respectively; while the Positive Predictive Value (PPV) and the Negative Predictive Value (NPV) were 87.4% and 100% respectively. This study therefore confirms that with proper meat inspection. a large proportion of tuberculosis cattle can be identified at postmortem. Hence. more emphasis should be directed at the improvement of meat inspection Services in Nigeria since there are no available laboratory facilities for the diagnosis of bovine tuberculosis in the abattoirs